Invitrogen

HLA-DR/DP/DQ Chimeric Recombinant Rabbit Monoclonal Antibody (F3.3)

HLA-DR/DP/DQ Chimeric Antibody in Western Blot (WB)

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HLA-DR/DP/DQ Chimeric Antibody (MA5-47832) in WB

Western Blot analysis of HLA-DR/DP/DQ was performed using HLA-DR/DP/DQ Chimeric Monoclonal Antibody (Product # MA5-47832). Human spleen (A), human tonsil (B) and Daudi cell lysate (C) samples (35 µg protein in RIPA buffer) were resolved on a 10% SDS PAGE gel and blots probed with HLA-DR/DP/DQ Chimeric Monoclonal Antibody at 0.01 µg/mL before detection using an anti-rabbit secondary antibody. A primary incub... View More

HLA-DR/DP/DQ Chimeric Antibody in Flow Cytometry (Flow)

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产品信息

MA5-47832

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.01 µg/mL

流式细胞分析 (Flow)

10 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG, kappa

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

F3.3

抗原

Proprietary sequence.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS

内含物

0.02% ProClin 300

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_3074278

产品详细信息

Specificity: Recognising anti-class II HLA molecules.

靶标信息

MHC class II molecules are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, thymic epithelial cells and activated T lymphocytes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They therefore have a critical role in the initiation of the immune response.

HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: beta1 domain MHC class II HLA DPB; class II HLA beta chain; DR beta-5; DR-9; DR2-beta-2; DR7; DR9; DRB1 transplantation antigen; Dw2; DW2.2/DR2.2; FLJ75017; FLJ76359; histocompatibility antigen HLA-DR alpha; HLA class II antigen; HLA class II histocompatibility antigen, DP beta 1 chain; HLA class II histocompatibility antigen, DP(W4) beta chain; HLA class II histocompatibility antigen, DQ beta 1 chain; HLA class II histocompatibility antigen, DR alpha chain; HLA class II histocompatibility antigen, DR beta 3 chain; HLA class II histocompatibility antigen, DR beta 4 chain; HLA class II histocompatibility antigen, DR beta 5 chain; HLA class II histocompatibility antigen, DR-1 beta chain; HLA class II histocompatibility antigen, DR-5 beta chain; HLA class II histocompatibility antigen, DRB1 beta chain; HLA class II histocompatibility antigen, DRB1-7 beta chain; HLA class II histocompatibility antigen, DRB1-9 beta chain; HLA DP14-beta chain; HLA-D; HLA-DP histocompatibility type, beta-1 subunit; HLA-DQ; HLA-DR; HLA-DRB1; HLA-DRB5; human leucocyte antigen DRB1; human leucocyte antigen DRB3; human leucocyte antigen DRB4; human leucocyte antigen DRB5; Human leukocyte antigen DRB1; leukocyte antigen; leukocyte antigen class II; lymphocyte antigen; lymphocyte antigen DRB1; major histocompatibility complex class II antigen beta chain; MHC cell surface glycoprotein; MHC Class 2; MHC class I antigen; MHC class II; MHC Class II antigen; MHC class II antigen beta chain; MHC class II antigen DP beta 1 chain; MHC class II antigen DPB1; MHC class II antigen DPbeta1; MHC class II antigen DQB1; MHC class II antigen DR beta 3 chain; MHC class II antigen DRA; MHC class II antigen DRB1*9; MHC class II antigen DRB3; MHC class II antigen DRB4; MHC class II antigen DRB5; MHC class II antigen HLA-DQ-beta-1; MHC class II antigen HLA-DR-beta; MHC class II DQ beta chain; MHC class II HLA beta chain; MHC class II HLA-DP-beta-1; MHC class II HLA-DQ beta glycoprotein; MHC class II HLA-DR beta 1 chain; MHC class II HLA-DR beta 3 chain; MHC class II HLA-DR-beta cell surface glycoprotein; MHC class II HLA-DRB1; MHC class II HLA-DRw10-beta; MHC class2 antigen; MHC DQ beta; MHC HLA DPB1; MHC HLA DR-beta chain; MHC HLA-D; MHC HLA-DR-beta cell surface glycoprotein; MHC HLA-DR-beta chain; MHC II HLA; XXbac-BPG161M6.1

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基因别名: CELIAC1; DPB1; DR-4; DR4; DRB1; DRB4; DRw10; HLA-DP; HLA-DP1B; HLA-DPB; HLA-DPB1; HLA-DQB; HLA-DQB1; HLA-DR1B; HLA-DR3B; HLA-DR4B; HLA-DRA; HLA-DRA1; HLA-DRB; HLA-DRB1; HLA-DRB3; HLA-DRB4; HLA-DRB5; IDDM1; MLRW; SS1