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HOXB8 Antibody (PA5-81200) in WB
Western Blot using HOXB8 Polyclonal Antibody (Product # PA5-81200) at 1:500 dilution. Lane A: Mouse brain tissue lysate, Lane B: Rat brain tissue lysate. Lysates/proteins at 30 µg per lane. Secondary Goat Anti-Rabbit IgG H&L (DyLight™ 800) at 1:10,000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 28 kDa. Observed band size: 28 kDa. (We are unsure of the identity of these extra bands).
产品信息
PA5-81200
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to the center region of the Human HOXB8
偶联物
Unconjugated
形式
Liquid
浓度
5 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2788429
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human HOXB8.
靶标信息
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: homeo box 2D; homeo box B8; Homeobox protein Hox-2.4; Homeobox protein Hox-2D; Homeobox protein Hox-B8
基因别名: Hox-2.4; HOX2; HOX2D; HOXB8
UniProt ID: (Human) P17481
Entrez Gene ID: (Human) 3218
transcription, DNA-templated
regulation of transcription, DNA-templated
grooming behavior
adult locomotory behavior
anterior/posterior pattern specification
sensory perception of pain
dorsal spinal cord development
negative regulation of myeloid cell differentiation
embryonic skeletal system morphogenesis
