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HOXD8 Antibody (PA5-23476) in WB
Western blot analysis of HOXD8 in T98G cell lysate in the 1) pre-bleed at 1:5000 dilution 2) T98G cell lysate and 3) NIH 3T3 cell lysate. Samples were incubated in HOXD8 polyclonal antibody (Product # PA5-23476) followed by a goat anti-rabbit Ig HRP secondary antibody. PicoTect ECL substrate solution was used for this test.
产品信息
PA5-23476
产品规格
种属反应
Human,
Mouse,
Non-human primate
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A portion of amino acids 250-290 of human HOXD8
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS with 0.05% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2540976
靶标信息
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: homeo box 4E; homeo box D8; homeobox protein 5.4; Homeobox protein Hox-4.3; Homeobox protein Hox-4E; Homeobox protein Hox-5.4; Homeobox protein Hox-D8; Hox-4.5
基因别名: 4921540P06Rik; AI047735; Hox-4.3; Hox-5.4; HOX4; HOX4E; HOX5.4; Hoxd-8; HOXD8
UniProt ID: (Human) P13378, (Mouse) P23463
Entrez Gene ID: (Human) 3234, (Mouse) 15437
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
multicellular organism development
anterior/posterior pattern specification
positive regulation of transcription from RNA polymerase II promoter
skeletal system morphogenesis
anterior/posterior axis specification, embryo
