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Immunogen sequence: QDVVDLDFF TQEPLHLVSP SFLSVTIDAN LATDPRFLIL LGSPKLRTLA RGLSPAYLRF GGTKTDFLIF DPKKESTFEE RSYWQSQVNQ DICKYGSIPP DVEEKLRLEW PYQEQLLLRE HYQKKFKNST YSRSSVDVLY TFANCSGLDL IFGLNALLRT ADLQWNSSNA QLLLDYCSSK GYNISWELGN EPNSFLKKAD IFINGSQLGE DFIQLHKLLR KSTFKNAKLY GPDVGQPRRK TAKMLKSFLK AGGEVIDSVT WHHYYLNGRT ATREDFLNPD VLDIFISSVQ KVFQVVESTR PGKKVWLGET SSAYGGGAPL LSDTFAAGFM WLDKLGLSAR MGIEVVMRQV FFGAGNYHLV DENFDPLPDY WLSLLFKKLV GTKVLMASVQ GSKRRKLRVY LHCTNTDNPR YKEGDLTLYA INLHNVTKYL RLPYPFSNKQ VDKYLLRPLG PHGLLSKSVQ LNGLTLKMVD DQTLPPLMEK PLRPGSSLGL PAFSYSFFVI RNAKVAACI (36-543 aa encoded by BC051321)
Stem cells offer a therapeutic promise for many diseases. In the case of diabetes, stem cells offer the promise that beta cells may be generated ex vivo for the possible transplantation and cure of Type I diabetes (Couri CE, et al. ). For this to happen, stem cells will need to be isolated and expanded, they will need to be differentiated toward the beta cell lineage, and the differentiated cell progeny used for transplantation may need to be isolated from complex cell mixtures following differentiation. Appropriate markers targeting cell surface molecules on developing and mature pancreatic cells will be required for such research.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Endo-glucoronidase; endoglycosidase heparanase; Heparanase; Heparanase-1; Hpa1
基因别名: HEP; HPA; HPA1; HPR1; HPSE; HPSE1; HSE1
UniProt ID: (Human) Q9Y251, (Mouse) Q6YGZ1
Entrez Gene ID: (Human) 10855, (Mouse) 15442