Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
PA5-33846
产品规格
种属反应
Bovine,
Horse,
Guinea pig,
Hamster,
Human,
Mouse,
Non-human primate,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 16 amino acid peptide from 2nd cytoplasmic domain of human HRH3 / Histamine H3 Receptor.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2551215
产品详细信息
This antibody is not recommended for use in WB applications.
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Rat, Hamster, Elephant, Bovine, Horse, Guinea pig (100%).
靶标信息
H3 Histamine Receptor regulates the release of the neurotransmitters norepinephrine and somatostatin. In histamine-containing neurons of the brain, the H3 receptor acts as a presynaptic autoreceptor, while in nonhistamine-containing neurons, in both the central and peripheral nervous systems, it acts as a presynaptic heteroreceptor. Multiple isoforms of H3 receptors are produced by alternative splicing. Histamine H3 receptor has been reported primarily in brain. ESTs have been isolated from brain (normal and cancer), breast cancer, colon cancer, and retinoblastoma libraries.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: G protein-coupled receptor 97; G-protein coupled receptor 97; H3R; HH3R; Histamine H3 receptor; histamine H3 receptor H3L isoform; histamine receptor; histamine receptor H 3; histamine receptor H3
基因别名: AW049250; GPCR97; H3R; HH3R; HRH3; I79_009854
UniProt ID: (Human) Q9Y5N1, (Rat) Q9QYN8, (Guinea pig) Q9JI35, (Mouse) P58406
Entrez Gene ID: (Horse) 100058016, (Human) 11255, (Rat) 85268, (Guinea pig) 100135541, (Chinese hamster) 100764853, (Mouse) 99296
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway
phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
neurotransmitter secretion
synaptic transmission, cholinergic
negative regulation of glutamate secretion
regulation of norepinephrine secretion
negative regulation of serotonin secretion
cognition
regulation of neurotransmitter levels
G-protein coupled receptor signaling pathway
negative regulation of adenylate cyclase activity
positive regulation of cytosolic calcium ion concentration
brain development
learning
memory
negative regulation of gamma-aminobutyric acid secretion
response to organic cyclic compound
eating behavior
drinking behavior
negative regulation of blood pressure
positive regulation of epithelial cell proliferation
signal transduction
sensory perception of chemical stimulus
