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产品信息
PA5-65521
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
Unconjugated
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2665144
产品详细信息
Immunogen sequence: GKGSFSPEGPR NAQQPEPGDP REIPDRGPLG LESGDRSPES LLPPMLLQPP QESVEPAGPL DVLGPSLQGR EWTLMDLDME LSLMQPLVPE RGEPELAVKG LNSPSP
Highest antigen sequence identity to the following orthologs - mouse 74%, rat 74%.
靶标信息
Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described.
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生物信息学
蛋白别名: AT-HSFB1; ATHSF4; cataract; Heat shock factor protein 4; Heat shock transcription factor 4; hHSF4; HSF 4; HSFB1; HSTF 4; Marner
基因别名: CTM; CTRCT5; HSF4
UniProt ID: (Human) Q9ULV5
Entrez Gene ID: (Human) 3299
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
visual perception
positive regulation of cell proliferation
histone H3-K9 demethylation
camera-type eye development
positive regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
cell development
protein homotrimerization
