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In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Heat shock 70 kDa protein 2; heat shock 70kD protein 2; heat shock 70kDa protein 2; Heat shock protein; Heat shock protein family A member 2; Heat shock-related 70 kDa protein 2; HSP
基因别名: HSP70-2; HSP70-3; HSPA2
UniProt ID: (Human) P54652
Entrez Gene ID: (Human) 3306