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5-HT1F is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. 5-HT1F is a member of the GPCR family. Expression of 5-HT1F has been reported in various brain structures, including cortex, hippocampus, trigeminal ganglia, and cerebral blood vessels. Expression in peripheral tissues is limited to uterus, mesentery, and artery. No expression has been detected in heart, kidney, liver, pancreas, or spleen.
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蛋白别名: 5-HT-1E-beta; 5-HT-1F; 5-HT1F; 5-HT1f receptor; 5-hydroxytryptamine (serotonin) receptor 1E beta; 5-hydroxytryptamine (serotonin) receptor 1F; 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled; 5-hydroxytryptamine 1E receptor; 5-hydroxytryptamine 1F receptor; 5-hydroxytryptamine receptor; 5-hydroxytryptamine receptor 1F; 5HT1F Receptor; Serotonin receptor 1F; serotonin receptor gene (similar to Mm Htr1eb)
基因别名: 5-HT-1F; 5-HT1F; 5ht1f; 5HT6; 5htr1e; 5htr1f; Htr1eb; HTR1EL; HTR1F; I79_002827; MR77
UniProt ID: (Human) P30939, (Mouse) Q02284, (Guinea pig) O08890