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产品信息
PA1-41033
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptides corresponding to residues 27-42 and 427-442 of rat 5-HT3A receptor.
偶联物
形式
Liquid
浓度
1.0 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2248968
产品详细信息
Suggested positive control: human brain tissue, human brain protein.
靶标信息
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine, a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 5-HT-3; 5-HT3 receptor; 5-HT3-A; 5-HT3A; 5-HT3R; 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic; 5-hydroxytryptamine receptor 3; 5-hydroxytryptamine receptor 3A; 5HT3 serotonin receptor; serotonin receptor; Serotonin receptor 3A; Serotonin-gated ion channel receptor; truncated receptor
基因别名: 5-HT-3; 5-HT3; 5-HT3A; 5-HT3R; 5HT3; 5HT3R; HTR3; HTR3A
UniProt ID: (Human) P46098, (Rat) P35563, (Mouse) P23979
Entrez Gene ID: (Human) 3359, (Rat) 79246, (Mouse) 15561
acetylcholine-activated cation-selective channel activity
serotonin-activated cation-selective channel activity
voltage-gated potassium channel activity
protein binding
acetylcholine receptor activity
serotonin-gated cation channel activity
acetylcholine binding
serotonin binding
G-protein coupled serotonin receptor activity
extracellular ligand-gated ion channel activity
ligand-gated ion channel activity
ligand-gated ion channel
signal transduction
synaptic transmission, cholinergic
ion transmembrane transport
response to cocaine
response to ethanol
cellular response to growth factor stimulus
potassium ion transmembrane transport
cation transport
serotonin receptor signaling pathway
chemical synaptic transmission
cation transmembrane transport
transport
ion transport
regulation of ion transmembrane transport
