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Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: LHPTLVSFAH EDKNSPPKEE GLCCPPPVPS NGPMQPLGSP NCVKSRGRFP MMGIGQMLRK RHQSLQPSAD RPLEASLPPL QPLAPVNLAF DMADGVKTQC
HUNK serine/threonine kinase or hormonally up-regulated Neu-associated kinase is a member of the mitogen-activated protein kinase family which is essential for mammary tumor metastasis. HUNK deletion in mice did not alter viability, fertility, longevity, or propensity to develop tumors and it is also dispensable for murine development. HUNK has been shown to participate in vesicular transport. Additionally, functional studies in mice suggest that HUNK regulates endocytosis via interaction with rabaptin-5 protein and induces changes in mammary glands during pregnancy. HUNK expression has been documented in mouse brain, breast, embryo, and fetus. ESTs have been isolated from several human tissue libraries, including normal ear.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: B19; Hormonally up-regulated neu tumor-associated kinase; hormonally upregulated neu tumor-associated kinase; hormonally upregulated Neu-associated kinase; serine/threonine protein kinase MAK-V; Serine/threonine-protein kinase MAK-V
基因别名: HUNK; MAKV
UniProt ID: (Human) P57058
Entrez Gene ID: (Human) 30811
分子生物学功能:
non-receptor serine/threonine protein kinase
protein modifying enzyme