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产品信息
19430-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
HUWE1 Fusion Protein Ag13763 (3983-4374 aa encoded by BC002602)
偶联物
Unconjugated
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: AVLVDYIRV LDFDVKRKYF RQELERLDEG LRKEDMAVHV LRDHVFEDSY RELHRKSPEE MKNRLYIVFE GEEGQDAGGL LREWYMIISR EMFNPMYALF RTSPGDRVTY TINPSSHCNP NHLSYFKFVG RIVAKAVYDN RLLECYFTRS FYKHILGKSV RYTDMESEDY HFYQGLVYLL ENDVSTLGYD LTFSTEVQEF GVCEVRDLKP NGANILVTEE NKKEYVHLVC QMRMTGAIRK QLAAFLEGFY EIIPKRLISI FTEQELELLI SGLPTIDIDD LKSNTEYHKY QSNSIQIQWF WRALRSFDQA DRAKFLQFVT GTSKVPLQGF AALEGMNGIQ KFQIHRDDRS TDRLPSAHTC FNQLDLPAYE SFEKLRHMLL LAIQECSEGF GLA (3983-4374 aa encoded by BC002602)
靶标信息
SUFU encodes a component of the Sonic hedgehog (SHH; MIM 600725)/Patched (PTCH; MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945; BCNS, MIM 109400; and GCPS, MIM 175700).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: ARF-binding protein 1; ARF-BP1; BJ-HCC-24 tumor antigen; E3 ubiquitin-protein ligase HUWE1; E3Histone; HECT domain protein LASU1; HECT, UBA and WWE domain-containing protein 1; HECT-type E3 ubiquitin transferase HUWE1; HectH9; Homologous to E6AP carboxyl terminus homologous protein 9; Large structure of UREB1; LASU1; Mcl-1 ubiquitin ligase; Mcl-1 ubiquitin ligase E3; Mule; RP3-339A18.4; upstream regulatory element binding protein 1; Upstream regulatory element-binding protein 1; URE-B1; URE-binding protein 1
基因别名: 5430439H10Rik; ARF-BP1; AU041296; C430014N20Rik; C80292; Gm1718; HECTH9; HSPC272; HUWE1; Ib772; KIAA0312; KIAA1578; LASU1; MULE; URE-B1; UREB1
UniProt ID: (Human) Q7Z6Z7, (Mouse) Q7TMY8
Entrez Gene ID: (Human) 10075, (Mouse) 59026
DNA binding
ubiquitin-protein transferase activity
protein binding
ligase activity
poly(A) RNA binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
ubiquitin-protein ligase
protein polyubiquitination
base-excision repair
protein monoubiquitination
histone ubiquitination
cell differentiation
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
positive regulation of protein targeting to mitochondrion
DNA repair
cellular response to DNA damage stimulus
