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Reconstitution: 1 X 25 µL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
HVCN1 (hydrogen voltage-gated channel 1), a voltage gated proton channel protein that is highly expressed in immune tissues, mediates the proton conductances required by phagocytic leukocytes for the oxidative burst that underlies microbial killing. HVCN1 moderates the voltage-dependent proton permeability of excitable membranes by allowing the flow of protons in accordance to their electrochemical gradient. HVCN1 is sensitive to zinc ions, and can be inhibited by them. HVCN1 may represent a new therapeutic target for B cell malignancies on continued signaling via the B cell antigen receptor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: HV1; Hydrogen voltage-gated channel 1; mVSOP; Voltage sensor domain-only protein; Voltage-gated hydrogen channel 1
基因别名: 0610039P13Rik; AI450555; BTS; HV1; HVCN1; mVSOP; RGD1310788; UNQ578/PRO1140; VSOP; Vsop.
UniProt ID: (Human) Q96D96, (Mouse) Q3U2S8
Entrez Gene ID: (Human) 84329, (Mouse) 74096, (Rat) 304485