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Invitrogen
Hemoglobin Monoclonal Antibody (HB11-231.2)
高级验证
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
图: 1 / 4
Hemoglobin Antibody (MA1-10808) in ICC/IF
Immunofluorescence analysis of Hemoglobin was performed using K-562 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with Hemoglobin Monoclonal Antibody (HB11-231.2) (Product # MA1-10808) at 1:100 dilution in 0.1% BSA, incubated at 4 degree celsius over... View More
产品信息
MA1-10808
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
HB11-231.2
抗原
Purified human hemoglobin.
偶联物
形式
Liquid
浓度
1.2 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_1075034
产品详细信息
MA1-10808 detects Hemoglobin from human samples. This antibody does not detect bovine, chicken, equine, ovine, or porcine Hemoglobin.
MA1-10808 has been successfully used in ELISA and Western blot applications.
The MA1-10808 immunogen is purified human hemoglobin.
靶标信息
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alpha one globin; alpha-1 globin; alpha-1-globin; alpha-2 globin chain; Alpha-globin; ALPHA-GLOBIN GENE; beta globin chain; Beta-globin; delta globin; Haemoglobin; Hb; HbA1c; hemoglobin alpha 1 globin chain; Hemoglobin alpha chain; Hemoglobin beta chain; Hemoglobin subunit alpha; Hemoglobin subunit beta; hemoglobin, alpha 1; hemoglobin, beta
基因别名: beta-globin; CD113t-C; HBA-T3; HBA1; HBA2; HBB; HBH
UniProt ID: (Human) P69905, (Human) P68871
Entrez Gene ID: (Human) 3039, (Human) 3043
receptor-mediated endocytosis
blood coagulation
regulation of blood pressure
positive regulation of cell death
oxygen transport
bicarbonate transport
nitric oxide transport
response to hydrogen peroxide
hydrogen peroxide catabolic process
positive regulation of nitric oxide biosynthetic process
regulation of blood vessel size
protein heterooligomerization
renal absorption
platelet aggregation
cellular oxidant detoxification
