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NeoBiotechnologies
Positive Control: Human spleen lung or placenta. stomach cancer
Cellular Location: Extracellular space.
HBA2 located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: alpha globin; alpha one globin; alpha-1 globin; alpha-1-globin; alpha-2 globin; alpha-2 globin chain; Alpha-globin; delta globin; hemoglobin alpha 1 globin chain; Hemoglobin alpha chain; Hemoglobin subunit alpha; hemoglobin, alpha 1; hemoglobin, alpha 2; mutant hemoglobin alpha 2 globin chain
基因别名: HBA-T2; HBA-T3; HBA1; HBA2; HBH
UniProt ID: (Human) P69905
Entrez Gene ID: (Human) 3039, (Human) 3040