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Invitrogen
Hemoglobin alpha Recombinant Rabbit Monoclonal Antibody (ARC1510)
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Hemoglobin alpha Antibody (MA5-35794) in IHC (P)
Immunohistochemistry analysis of Hemoglobin alpha in paraffin-embedded blood cell staining in human placenta. Samples were incubated with Hemoglobin alpha Monoclonal antibody (Product # MA5-35794) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
产品信息
MA5-35794
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
ARC1510
抗原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Hemoglobin subunit alpha (HBA1) (HBA1) (P69905)
偶联物
形式
Liquid
浓度
0.8 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2849694
产品详细信息
Immunogen sequence: MVLSPADKTN VKAAWGKVGA HAGEYGAEAL ERMFLSFPTT KTYFPHFDLS HGSAQVKGHG KKVADALTNA VAHVDDMPNA LSALSDLHAH KLRVDPVNFK
靶标信息
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alpha 1 globin; alpha globin 1; alpha one globin; Alpha-1/2-globin; alpha-2 globin chain; Alpha-globin; delta globin; globin, alpha; haemaglobin alpha 1; hemoglobin alpha 1 chain; hemoglobin alpha 1 globin chain; Hemoglobin alpha chain; hemoglobin alpha, adult chain 1; hemoglobin alpha, adult chain 2; Hemoglobin alpha-1/2 chain; Hemoglobin subunit alpha; Hemoglobin subunit alpha-1/2; hemoglobin, alpha 1
基因别名: GloA; Hba; Hba-a1; Hba-a2; HBA-T3; HBA1; HBA2; HBAM; Hbat1; HBH
UniProt ID: (Human) P69905, (Rat) P01946
Entrez Gene ID: (Human) 3039, (Mouse) 15122, (Rat) 25632, (Rat) 287167
in utero embryonic development
erythrocyte development
positive regulation of cell death
oxygen transport
response to hydrogen peroxide
hydrogen peroxide catabolic process
protein heterooligomerization
oxidation-reduction process
receptor-mediated endocytosis
bicarbonate transport
cellular oxidant detoxification
negative regulation of blood pressure
regulation of sensory perception of pain
