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Goats were immunized with purified human ceruloplasmin of serum or plasma origin. The antibody was isolated by affinity chromatography using antigen coupled to agarose beads. Antibody concentration was determined by extinction coefficient: absorbance at 280 nm of 1.4 equals 1.0 mg of IgG.
Ceruloplasmin encodes a protein that is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Ceruloplasmin; Cuproxidase ceruloplasmin; Ferroxidase ceruloplasmin; Glutathione peroxidase ceruloplasmin; Glutathione-dependent peroxiredoxin ceruloplasmin
基因别名: CP; CP-2
UniProt ID: (Human) P00450
Entrez Gene ID: (Human) 1356