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The antibody binds to human TNF-alpha with a Kd of 0.087 nM.
The structure of Humicade is a monoclonal antibody that is highly similar to the reference medicine, Humira (adalimumab). It is composed of human immunoglobulin G1 (IgG1) antibodies that are produced using recombinant DNA technology. The function of Humicade is to treat certain autoimmune conditions by blocking the action of tumor necrosis factor-alpha (TNF-alpha), a protein that contributes to inflammation. The structure of Humicade allows it to specifically target TNF-alpha and block its activity, reducing inflammation and alleviating symptoms in certain autoimmune conditions.
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