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ICOS Antibody (MA5-35654) in WB
Western blot analysis of ICOS in extracts of various cell lines. Samples were incubated with ICOS Monoclonal antibody (Product # MA5-35654) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
MA5-35654
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
ARC1148
抗原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ICOS/CD278 (Q9Y6W8)
偶联物
形式
Liquid
浓度
2 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2849554
产品详细信息
Immunogen sequence: MKSGLWYFFL FCLRIKVLTG EINGSANYEM FIFHNGGVQI LCKYPDIVQQ FKMQLLKGGQ ILCDLTKTKG SGNTVSIKSL KFCHSQLSNN SVSFFLYNLD
靶标信息
ICOS (CD278) encodes a protein that is a member of the CD28 and CTLA-4 cell-surface receptor family. It functions as a homodimer and has a crucial role in cell-cell signaling, immune responses, and the regulation of cell proliferation. ICOS has been linked to various disorders, including Immunodeficiency, Common Variable, 1 and Common Variable Immunodeficiency.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Activation-inducible lymphocyte immunomediatory molecule; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; inducible costimulator; inducible T-cell co-stimulator; Inducible T-cell costimulator
基因别名: AILIM; CCLP; CD278; CRP-1; CVID1; H4; ICOS; Ly115
UniProt ID: (Human) Q9Y6W8, (Rat) Q9R1T7, (Mouse) Q9WVS0
Entrez Gene ID: (Human) 29851, (Rat) 64545, (Mouse) 54167
