Invitrogen

IDH3A Polyclonal Antibody

IDH3A Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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IDH3A Antibody (PA5-142769) in IHC (P)

Immunohistochemistry analysis of IDH3A in human thymus. Samples were incubated with IDH3A polyclonal antibody (Product # PA5-142769) using a dilution of 3.75 µg/mL. Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

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产品信息

PA5-142769

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.1-0.3 µg/mL

免疫组化（石蜡） (IHC (P))

3.75 µg/mL

产品规格

种属反应

Human, Mouse, Pig, Rat

宿主/亚型

Goat / IgG

分类

Polyclonal

类型

Antibody

抗原

Peptide with sequence DFTEEICRRVKDLD.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Ammonium sulfate precipitation

保存液

TBS, pH 7.3, with 0.5% BSA

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

RRID

AB_2933415

产品详细信息

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.

靶标信息

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein described here is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: H-IDH alpha; isocitrate dehydrogenase (NAD(+)) 3 alpha; isocitrate dehydrogenase (NAD+) alpha chain; isocitrate dehydrogenase 3 (NAD(+)) alpha; isocitrate dehydrogenase 3 (NAD+) alpha; Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; NAD(H)-specific isocitrate dehydrogenase alpha subunit; NAD+-specific ICDH

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基因别名: 1110003P10Rik; 1500012E04Rik; AA407078; AI316514; IDH3A