Product References
Hypoxia induces HIF1α-dependent epigenetic vulnerability in triple negative breast cancer to confer immune effector dysfunction and resistance to anti-PD-1 immunotherapy.
Nature communications
Ma S,Zhao Y,Lee WC,Ong LT,Lee PL,Jiang Z,Oguz G,Niu Z,Liu M,Goh JY,Wang W,Bustos MA,Ehmsen S,Ramasamy A,Hoon DSB,Ditzel HJ,Tan EY,Chen Q,Yu Q
MM700 was used in Immunohistochemistry to identify a HIF1α-mediated epigenetic mechanism in immune dysfunction and provide a potential strategy to overcome immune resistance in TNBC.
Fri Jul 15 00:00:00 EDT 2022
Improved intratumoral penetration of IL12 immunocytokine enhances the antitumor efficacy.
Frontiers in immunology
Jung K,Yoo S,Kim JE,Kim W,Kim YS
MM700 was used in Immunohistochemistry-immunofluorescence to investigate the influence of the tumor antigen-binding kinetics of a murine interleukin 12 (mIL12)-based immunocytokine on tumor localization and diffusive intratumoral penetration, and hence the consequent antitumor activity, by activating effector T cells in immunocompetent mice bearing syngeneic colon tumors.
Tue Nov 22 00:00:00 EST 2022
Essential Role of IFN-γ in Regulating Gut Antimicrobial Peptides and Microbiota to Protect Against Alcohol-Induced Bacterial Translocation and Hepatic Inflammation in Mice.
Frontiers in physiology
Yue R,Wei X,Zhao J,Zhou Z,Zhong W
Published figure using IFN gamma monoclonal antibody (Product # MM700) in Immunohistochemistry
Thu Feb 11 00:00:00 EST 2021
Essential Role of IFN-γ in Regulating Gut Antimicrobial Peptides and Microbiota to Protect Against Alcohol-Induced Bacterial Translocation and Hepatic Inflammation in Mice.
Frontiers in physiology
Yue R,Wei X,Zhao J,Zhou Z,Zhong W
Published figure using IFN gamma monoclonal antibody (Product # MM700) in Immunohistochemistry
Thu Feb 11 00:00:00 EST 2021
A micropeptide encoded by lncRNA MIR155HG suppresses autoimmune inflammation via modulating antigen presentation.
Science advances
Niu L,Lou F,Sun Y,Sun L,Cai X,Liu Z,Zhou H,Wang H,Wang Z,Bai J,Yin Q,Zhang J,Chen L,Peng D,Xu Z,Gao Y,Tang S,Fan L,Wang H
MM700 was used in Flow Cytometry to demonstrate the endogenous existence of a micropeptide encoded by a transcript annotated as "non-protein coding" and characterize a micropeptide as a regulator of antigen presentation and a suppressor of inflammatory diseases.
Fri May 01 00:00:00 EDT 2020
Diverse CD8 T Cell Responses to Viral Infection Revealed by the Collaborative Cross.
Cell reports
Martin MD,Sompallae R,Winborn CS,Harty JT,Badovinac VP
MM700 was used in an ELISA assay to advance the utility of the Collaborative Cross (CC) as a tool to analyze the immune response to viral infection.
Tue Apr 14 00:00:00 EDT 2020
IL-17RA-Signaling Modulates CD8+ T Cell Survival and Exhaustion During Trypanosoma cruzi Infection.
Frontiers in immunology
Tosello Boari J,Araujo Furlan CL,Fiocca Vernengo F,Rodriguez C,Ramello MC,Amezcua Vesely MC,Gorosito Serrán M,Nuñez NG,Richer W,Piaggio E,Montes CL,Gruppi A,Acosta Rodríguez EV
MM700 was used in Flow cytometry/Cell sorting to demonstrate that IL-17RA-signalling cytokines sustain pathogen-specific CD8+ T cell immunity.
Thu Oct 03 00:00:00 EDT 2019
Cytochrome c Oxidase Activity Is a Metabolic Checkpoint that Regulates Cell Fate Decisions During T Cell Activation and Differentiation.
Cell metabolism
Tarasenko TN,Pacheco SE,Koenig MK,Gomez-Rodriguez J,Kapnick SM,Diaz F,Zerfas PM,Barca E,Sudderth J,DeBerardinis RJ,Covian R,Balaban RS,DiMauro S,McGuire PJ
MM700 was used in Flow cytometry/Cell sorting to understand the mechanism of cytochrome c oxidase regulation of OXPHOS using a mouse model with isolated dysfunction in T cells by targeting the COX10 gene which produces mitochondrial disease in humans.
Tue Jun 06 00:00:00 EDT 2017
Defective germinal center B-cell response and reduced arthritic pathology in microRNA-29a-deficient mice.
Cellular and molecular life sciences : CMLS
van Nieuwenhuijze A,Dooley J,Humblet-Baron S,Sreenivasan J,Koenders M,Schlenner SM,Linterman M,Liston A
MM700 was used in flow cytometry to evaluate miR-29a in B cells as a potential therapeutic target in arthritis
Thu Jun 01 00:00:00 EDT 2017
Transcriptional determinants of tolerogenic and immunogenic states during dendritic cell maturation.
The Journal of cell biology
Vander Lugt B,Riddell J,Khan AA,Hackney JA,Lesch J,DeVoss J,Weirauch MT,Singh H,Mellman I
MM700 was used in flow cytometry to elucidate the role of interferon regulatory factor 4 in dendritic cells
Mon Mar 06 00:00:00 EST 2017
Host-Derived CD70 Suppresses Murine Graft-versus-Host Disease by Limiting Donor T Cell Expansion and Effector Function.
Journal of immunology (Baltimore, Md. : 1950)
Leigh ND,O'Neill RE,Du W,Chen C,Qiu J,Ashwell JD,McCarthy PL,Chen GL,Cao X
MM700 was used in Flow cytometry/Cell sorting to demonstrate that host CD70 serves as a unique negative regulator of allogeneic T cell response by contributing to donor T cell apoptosis and inhibiting expansion of donor effector T cells.
Sat Jul 01 00:00:00 EDT 2017
IL-10 Plays Opposing Roles during Staphylococcus aureus Systemic and Localized Infections.
Journal of immunology (Baltimore, Md. : 1950)
Leech JM,Lacey KA,Mulcahy ME,Medina E,McLoughlin RM
MM700 was used in flow cytometry to define the functions of IL-10 during Staphylococcus aureus
Wed Mar 15 00:00:00 EDT 2017
Microsomal Prostaglandin E Synthase-1 Facilitates an Intercellular Interaction between CD4⁺ T Cells through IL-1β Autocrine Function in Experimental Autoimmune Encephalomyelitis.
International journal of molecular sciences
Takemiya T,Takeuchi C,Kawakami M
Published figure using IFN gamma monoclonal antibody (Product # MM700) in Immunohistochemistry
Tue Dec 19 00:00:00 EST 2017
Microsomal Prostaglandin E Synthase-1 Facilitates an Intercellular Interaction between CD4⁺ T Cells through IL-1β Autocrine Function in Experimental Autoimmune Encephalomyelitis.
International journal of molecular sciences
Takemiya T,Takeuchi C,Kawakami M
Published figure using IFN gamma monoclonal antibody (Product # MM700) in Immunohistochemistry
Tue Dec 19 00:00:00 EST 2017
Th40 cells (CD4+CD40+ Tcells) drive a more severe form of Experimental Autoimmune Encephalomyelitis than conventional CD4 T cells.
PloS one
Vaitaitis GM,Yussman MG,Waid DM,Wagner DH
MM700 was used in flow cytometry to find that Th40 cells drive a rapid, more severe experimental autoimmune encephalomyelitis disease course than conventional CD4 T cells
Tue Aug 29 00:00:00 EDT 2017
CD40-signalling abrogates induction of RORγt+ Treg cells by intestinal CD103+ DCs and causes fatal colitis.
Nature communications
Barthels C,Ogrinc A,Steyer V,Meier S,Simon F,Wimmer M,Blutke A,Straub T,Zimber-Strobl U,Lutgens E,Marconi P,Ohnmacht C,Garzetti D,Stecher B,Brocker T
MM700 was used in flow cytometry to report a CD40-dependent mechanism capable of abrogating inducible T regulatory cell induction by dendritic cells
Thu Mar 09 00:00:00 EST 2017
Combined toll-like receptor 3/7/9 deficiency on host cells results in T-cell-dependent control of tumour growth.
Nature communications
Klein JC,Moses K,Zelinskyy G,Sody S,Buer J,Lang S,Helfrich I,Dittmer U,Kirschning CJ,Brandau S
MM700 was used in flow cytometry to find that TLR3, 7 and 9 deficiencies on host cells result in complete tumor regression and induction of anti-tumor immunity
Thu Mar 16 00:00:00 EDT 2017
Characterization of c-Maf+Foxp3- Regulatory T Cells Induced by Repeated Stimulation of Antigen-Presenting B Cells.
Scientific reports
Chien CH,Yu HC,Chen SY,Chiang BL
MM700 was used in flow cytometry to generate and characterize Treg-of-B cells
Wed Apr 12 00:00:00 EDT 2017
Antitumor adaptive immunity remains intact following inhibition of autophagy and antimalarial treatment.
The Journal of clinical investigation
Starobinets H,Ye J,Broz M,Barry K,Goldsmith J,Marsh T,Rostker F,Krummel M,Debnath J
MM700 was used in flow cytometry to test how inhibiting autophagy impacts antitumor immune responses in immune-competent mouse models of melanoma and mammary cancer
Thu Dec 01 00:00:00 EST 2016
Differential Role of Hematopoietic and Nonhematopoietic Cell Types in the Regulation of NK Cell Tolerance and Responsiveness.
Journal of immunology (Baltimore, Md. : 1950)
Shifrin NT,Kissiov DU,Ardolino M,Joncker NT,Raulet DH
MM700 was used in flow cytometry to study the role of MCH I in natural killer cell tolerance and hyporesponsiveness
Tue Nov 15 00:00:00 EST 2016
Costimulation Endows Immunotherapeutic CD8 T Cells with IL-36 Responsiveness during Aerobic Glycolysis.
Journal of immunology (Baltimore, Md. : 1950)
Tsurutani N,Mittal P,St Rose MC,Ngoi SM,Svedova J,Menoret A,Treadway FB,Laubenbacher R,Suárez-Ramírez JE,Cauley LS,Adler AJ,Vella AT
MM700 was used in an ELISA assay to study how signal 3 responses function in dual-costimulated T cells.
Fri Jan 01 00:00:00 EST 2016
Severe Changes in Thymic Microenvironment in a Chronic Experimental Model of Paracoccidioidomycosis.
PloS one
Alves da Costa T,Di Gangi R,Thomé R,Barreto Felisbino M,Pires Bonfanti A,Lumi Watanabe Ishikawa L,Sartori A,Burger E,Verinaud L
MM700 was used in flow cytometry to examine the thymic microenvironment using a model of paracoccidioidomycosis
Mon May 22 00:00:00 EDT 2017
IL-25-responsive, lineage-negative KLRG1(hi) cells are multipotential 'inflammatory' type 2 innate lymphoid cells.
Nature immunology
Huang Y,Guo L,Qiu J,Chen X,Hu-Li J,Siebenlist U,Williamson PR,Urban JF,Paul WE
MM700 was used in Neutralization experiments to characterise the existence of an inflammatory ILC2 population responsive to interleukin 25 that complements IL-33-responsive natural ILC2 cells.
Sun Feb 01 00:00:00 EST 2015
DNAM-1 controls NK cell activation via an ITT-like motif.
The Journal of experimental medicine
Zhang Z,Wu N,Lu Y,Davidson D,Colonna M,Veillette A
MM700 was used in flow cytometry to study how DNAM-1 controls NK cell-mediated cytotoxicity and cytokine production
Mon Nov 16 00:00:00 EST 2015
Transcriptional repressor ZEB2 promotes terminal differentiation of CD8+ effector and memory T cell populations during infection.
The Journal of experimental medicine
Omilusik KD,Best JA,Yu B,Goossens S,Weidemann A,Nguyen JV,Seuntjens E,Stryjewska A,Zweier C,Roychoudhuri R,Gattinoni L,Bird LM,Higashi Y,Kondoh H,Huylebroeck D,Haigh J,Goldrath AW
MM700 was used in Flow Cytometry to study the upregulation of ZEB2 by activated T cells, specifically in the KLRG1(hi) effector CD8(+) T cell subset.
Mon Nov 16 00:00:00 EST 2015
An atypical CD8 T-cell response to Chlamydia muridarum genital tract infections includes T cells that produce interleukin-13.
Immunology
Johnson RM,Kerr MS,Slaven JE
MM700 was used in ELISA to study the mechanisms underlying CD8 T-cell-mediated pathology during genital tract Chlamydia infections and the significance of IL-13-producing cells
Sun Jun 01 00:00:00 EDT 2014
Anti-interleukin-10R1 monoclonal antibody in combination with bacillus Calmette--Guérin is protective against bladder cancer metastasis in a murine orthotopic tumour model and demonstrates systemic specific anti-tumour immunity.
Clinical and experimental immunology
Newton MR,Askeland EJ,Andresen ED,Chehval VA,Wang X,Askeland RW,O'Donnell MA,Luo Y
MM700 was used in ELISA to study the ability of a combination of an anti-IL-10R1 monoclonal antibody and BCG to protect against lung metastasis in bladder cancer patients
Tue Jul 01 00:00:00 EDT 2014
Rapid proliferation and differentiation impairs the development of memory CD8+ T cells in early life.
Journal of immunology (Baltimore, Md. : 1950)
Smith NL,Wissink E,Wang J,Pinello JF,Davenport MP,Grimson A,Rudd BD
MM700 was used in flow cytometry to investigate incomplete immunity against intracellular pathogens in neonates
Tue Jul 01 00:00:00 EDT 2014
Disorganized muscle protein-1 (DIM-1) of filarial parasite Brugia malayi: cDNA cloning, expression, purification, structural modeling and its potential as vaccine candidate for human filarial infection.
Vaccine
Kushwaha V,Kumar V,Verma SK,Sharma R,Siddiqi MI,Murthy PK
MM700 was used in ELISA to report on the cloning, expression and characterization of Brugia malayi DIM-1 and its potential as a vaccine against filarial infection in humans
Wed Mar 26 00:00:00 EDT 2014
Maternal immune stimulation during pregnancy shapes the immunological phenotype of offspring.
Brain, behavior, and immunity
Mandal M,Donnelly R,Elkabes S,Zhang P,Davini D,David BT,Ponzio NM
MM700 was used in flow cytometry to use poly(I:C)-injected dams to study the effects of inflammation on fetal development.
Tue Oct 01 00:00:00 EDT 2013
Imiquimod attenuates the growth of UVB-induced SCC in mice through Th1/Th17 cells.
Molecular carcinogenesis
Yokogawa M,Takaishi M,Nakajima K,Kamijima R,Digiovanni J,Sano S
MM700 was used in immunohistochemistry to study the role of Th1/Th17 cells in the attenuation of the growth of UVB-induced squamous cell carcinomas by imiquimod
Tue Oct 01 00:00:00 EDT 2013
Increased susceptibility of IgA-deficient mice to pulmonary Francisella tularensis live vaccine strain infection.
Infection and immunity
Furuya Y,Kirimanjeswara GS,Roberts S,Metzger DW
MM700 was used in flow cytometry to assess the lethality of primary F. tularensis live vaccine strain pulmonary infection in mice defective for IgA production.
Sun Sep 01 00:00:00 EDT 2013
Perforin is detrimental to controlling [corrected] C. muridarum replication in vitro, but not in vivo.
PloS one
Johnson RM,Kerr MS,Slaven JE
MM700 was used in ELISA to study the disparate effects of perforin on Chlamydia muridarum replication in vitro and iv vivo and the mechanistic implications
Mon Dec 30 00:00:00 EST 2013
Characterization of CD8+ T cell function and immunodominance generated with an H2O2-inactivated whole-virus vaccine.
Journal of virology
Walker JM,Raué HP,Slifka MK
MM700 was used in flow cytometry to investigate vaccine-induced CD8(+) T cell responses.
Sat Dec 01 00:00:00 EST 2012
Airway epithelial cells suppress T cell proliferation by an IFNγ/STAT1/TGFβ-dependent mechanism.
American journal of physiology. Lung cellular and molecular physiology
Deppong CM,Xu J,Brody SL,Green JM
MM700 was used in an ELISA assay to elucidate the mechanism by which airway epithelial cells suppress T cell proliferation.
Sun Jan 01 00:00:00 EST 2012
Plac8-dependent and inducible NO synthase-dependent mechanisms clear Chlamydia muridarum infections from the genital tract.
Journal of immunology (Baltimore, Md. : 1950)
Johnson RM,Kerr MS,Slaven JE
MM700 was used in ELISA to investigate Plac8-dependent and iNOS-dependent mechanisms of clearing Chlamydia muridarum genital tract infections
Wed Feb 15 00:00:00 EST 2012
PmpG303-311, a protective vaccine epitope that elicits persistent cellular immune responses in Chlamydia muridarum-immune mice.
Infection and immunity
Johnson RM,Yu H,Kerr MS,Slaven JE,Karunakaran KP,Brunham RC
MM700 was used in ELISA to study a protective vaccine epitope that elicits persistent cellular immune responses in Chlamydia muridarum-immune mice
Fri Jun 01 00:00:00 EDT 2012
Inchingorei-san (TJ-117) and Artemisiae Capillaris Herba Induced Prolonged Survival of Fully Mismatched Cardiac Allografts and Generated Regulatory Cells in Mice.
Evidence-based complementary and alternative medicine : eCAM
Jin X,Uchiyama M,Zhang Q,Hirai T,Niimi M
MM700 was used in ELISA to examine the effects of Inchingorei-san treatment on the alloimmune responses in a murine model of cardiac allograft transplantation
Thu Aug 23 00:00:00 EDT 2012
Ectonucleotidase CD38 demarcates regulatory, memory-like CD8+ T cells with IFN-γ-mediated suppressor activities.
PloS one
Bahri R,Bollinger A,Bollinger T,Orinska Z,Bulfone-Paus S
MM700 was used in Flow cytometry/Cell sorting to study how the expression of ectoenzyme receptor family members positively correlates with suppressor functions and identifies CD8(+)CD38(high) T cells as potential inhibitors of excessive immune responses.
Thu Feb 28 00:00:00 EST 2013
The secreted lipoprotein, MPT83, of Mycobacterium tuberculosis is recognized during human tuberculosis and stimulates protective immunity in mice.
PloS one
Kao FF,Mahmuda S,Pinto R,Triccas JA,West NP,Britton WJ
MM700 was used in ELISA to study the role of a secreted lipoprotein from of Mycobacterium tuberculosis in stimulating protective immunity
Mon Sep 17 00:00:00 EDT 2012
CD40-activated B cells can efficiently prime antigen-specific naïve CD8+ T cells to generate effector but not memory T cells.
PloS one
Mathieu M,Cotta-Grand N,Daudelin JF,Boulet S,Lapointe R,Labrecque N
MM700 was used in flow cytometry to test the ability of different types of antigen presenting cells to induce a CD8(+) T cell response.
Mon Jun 04 00:00:00 EDT 2012
Auditory stimulation of opera music induced prolongation of murine cardiac allograft survival and maintained generation of regulatory CD4+CD25+ cells.
Journal of cardiothoracic surgery
Uchiyama M,Jin X,Zhang Q,Hirai T,Amano A,Bashuda H,Niimi M
MM700 was used in ELISA to assess the effect of sounds on alloimmune responses in a murine model of cardiac allograft transplantation
Fri Mar 23 00:00:00 EDT 2012
Differential immune activation following encapsulation of immunostimulatory CpG oligodeoxynucleotide in nanoliposomes.
Biomaterials
Erikçi E,Gursel M,Gürsel I
MM700 was used in ELISA to evaluate the immune responses against nanoliposomes containing immunostimulatory CpG oligodeoxynucleotide
Tue Feb 01 00:00:00 EST 2011
Urothelial antigen-specific CD4+ T cells function as direct effector cells and induce bladder autoimmune inflammation independent of CD8+ T cells.
Mucosal immunology
Liu W,Chen X,Evanoff DP,Luo Y
MM700 was used in ELISA to investigate the role of specific CD4+ T cells in bladder autoimmune inflammation
Fri Jul 01 00:00:00 EDT 2011
Sensitization with anti-inflammatory BmAFI of Brugia malayi allows L3 development in the hostile peritoneal cavity of Mastomys coucha.
Acta tropica
Joseph SK,Verma SK,Sahoo MK,Dixit S,Verma AK,Kushwaha V,Saxena K,Sharma A,Saxena JK,Murthy PK
MM700 was used in ELISA to investigate the influence of sensitization with BmAFI on subsequent parasite development
Thu Dec 01 00:00:00 EST 2011
Adverse events post smallpox-vaccination: insights from tail scarification infection in mice with Vaccinia virus.
PloS one
Mota BE,Gallardo-Romero N,Trindade G,Keckler MS,Karem K,Carroll D,Campos MA,Vieira LQ,da Fonseca FG,Ferreira PC,Bonjardim CA,Damon IK,Kroon EG
MM700 was used in flow cytometry to determine the components of the host immune system that are sufficient to prevent morbidity/mortality in a murine model of smallpox
Fri Apr 15 00:00:00 EDT 2011
Polyinosinic-polycytidylic acid treatment of Friend retrovirus-infected mice improves functional properties of virus-specific T cells and prevents virus-induced disease.
Journal of immunology (Baltimore, Md. : 1950)
Gibbert K,Dietze KK,Zelinskyy G,Lang KS,Barchet W,Kirschning CJ,Dittmer U
MM700 was used in flow cytometry to use the Friend retrovirus mouse model to elucidate the mode of action of poly(I:C) in antiretroviral immunotherapy
Mon Nov 15 00:00:00 EST 2010
Two distinct chimeric potexviruses share antigenic cross-presentation properties of MHC class I epitopes.
Vaccine
Hanafi LA,Bolduc M,Gagné ME,Dufour F,Langelier Y,Boulassel MR,Routy JP,Leclerc D,Lapointe R
MM700 was used in ELISA to investigate virus-like particles from Potexviruses as a vaccine platform for inducing a CTL response.
Mon Aug 02 00:00:00 EDT 2010
RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F.
Gastroenterology
Leppkes M,Becker C,Ivanov II,Hirth S,Wirtz S,Neufert C,Pouly S,Murphy AJ,Valenzuela DM,Yancopoulos GD,Becher B,Littman DR,Neurath MF
MM700 was used in flow cytometry to ascertain the roles of Th17 cells and retinoic acid receptor-related organ receptor gamma in chronic intestinal inflammation
Thu Jan 01 00:00:00 EST 2009
Therapeutic targeting of IL-6 trans signaling counteracts STAT3 control of experimental inflammatory arthritis.
Journal of immunology (Baltimore, Md. : 1950)
Nowell MA,Williams AS,Carty SA,Scheller J,Hayes AJ,Jones GW,Richards PJ,Slinn S,Ernst M,Jenkins BJ,Topley N,Rose-John S,Jones SA
MM700 was used in flow cytometry to test the requirement for IL-6-mediated STAT3 signaling in orchestrating the inflammatory infiltrate in monoarticular and systemic models of experimental arthritis
Thu Jan 01 00:00:00 EST 2009
Early infection termination affects number of CD8+ memory T cells and protective capacities in listeria monocytogenes-infected mice upon rechallenge.
Journal of immunology (Baltimore, Md. : 1950)
Tseng KE,Chung CY,H'ng WS,Wang SL
MM700 was used in flow cytometry to assess the effects of early termination of infection on primary T cell expansion, subsequent memory cell development, and protective immunity
Wed Apr 15 00:00:00 EDT 2009
Homotypic T-cell/T-cell interaction induces T-cell activation, proliferation, and differentiation.
Human immunology
Ramming A,Thümmler K,Schulze-Koops H,Skapenko A
MM700 was used in blocking or activating experiment to study the role of homotypic T-cell/T-cell interactions in inducing the activation, proliferation, and differentiation of T-cells
Sun Nov 01 00:00:00 EDT 2009
Enhanced efficacy and reduced toxicity of multifactorial adjuvants compared with unitary adjuvants as cancer vaccines.
Blood
Ahonen CL,Wasiuk A,Fuse S,Turk MJ,Ernstoff MS,Suriawinata AA,Gorham JD,Kedl RM,Usherwood EJ,Noelle RJ
MM700 was used in Immunocytochemistry to report the therapeutic effects of combinatorial use of CD40 and TLR agonists as a cancer vaccine.
Sat Mar 15 00:00:00 EDT 2008
CD62L (L-selectin) down-regulation does not affect memory T cell distribution but failure to shed compromises anti-viral immunity.
Journal of immunology (Baltimore, Md. : 1950)
Richards H,Longhi MP,Wright K,Gallimore A,Ager A
MM700 was used in flow cytometry to investigate the distribution of CD62L on antigen-activated T cells and their ability to clear pathogen from peripheral sites
Tue Jan 01 00:00:00 EST 2008
Immunological diversity within a family of cutinase-like proteins of Mycobacterium tuberculosis.
Vaccine
West NP,Wozniak TM,Valenzuela J,Feng CG,Sher A,Ribeiro JM,Britton WJ
MM700 was used in ELISA to study the role of cutinase-like proteins in Mycobacterium tuberculosis
Wed Jul 23 00:00:00 EDT 2008
Overexpression of IL-21 promotes massive CD8+ memory T cell accumulation.
European journal of immunology
Allard EL,Hardy MP,Leignadier J,Marquis M,Rooney J,Lehoux D,Labrecque N
MM700 was used in flow cytometry to test the influences of IL-21 on cytokine receptor expression
Thu Nov 01 00:00:00 EDT 2007
Induction of robust diabetes resistance and prevention of recurrent type 1 diabetes following islet transplantation by gene therapy.
Journal of immunology (Baltimore, Md. : 1950)
Tian C,Ansari MJ,Paez-Cortez J,Bagley J,Godwin J,Donnarumma M,Sayegh MH,Iacomini J
MM700 was used in ELISA to determine whether the programmed death-1-programmed death ligand-1 pathway precipitates type 1 diabetes in young NOD mice
Thu Nov 15 00:00:00 EST 2007
Improvement of atopic dermatitis in NC/Nga mice by topical application of CpG phosphodiester-ODN.
International archives of allergy and immunology
Kim YS,Kim Y,Lee KJ,Kwon HJ,Kim DS,Kim TY
MM700 was used in immunohistochemistry to study the beneficial effects of topical CpG phosphodiester-oligonucleotides in murine atopic dermatitis
Tue Dec 18 00:00:00 EST 2007
Characterization of early gamma interferon (IFN-gamma) expression during murine listeriosis: identification of NK1.1+ CD11c+ cells as the primary IFN-gamma-expressing cells.
Infection and immunity
Chang SR,Wang KJ,Lu YF,Yang LJ,Chen WJ,Lin YH,Chang HH,Wang SL
MM700 was used in flow cytometry to identify the cells that are producing gamma interferon during infection with Listeria monocytogenes
Thu Mar 01 00:00:00 EST 2007
In vitro Th1 cytokine-independent Th2 suppressive effects of bifidobacteria.
Microbiology and immunology
Iwabuchi N,Takahashi N,Xiao JZ,Miyaji K,Iwatsuki K
MM700 was used in blocking or activating experiment to assess the role and mechanism of Bifidobacterium longum BB536 probiotic in suppressing antigen-induced Th2 immune response in vitro
Mon Dec 31 00:00:00 EST 2007
Oral attenuated Salmonella enterica serovar Typhimurium vaccine expressing codon-optimized HIV type 1 Gag enhanced intestinal immunity in mice.
AIDS research and human retroviruses
Tsunetsugu-Yokota Y,Ishige M,Murakami M
MM700 was used in ELISA to investigate the effect of oral attenuated Salmonella typhimurium vaccine
Thu Feb 01 00:00:00 EST 2007
COX-2 inhibitors modulate IL-12 signaling through JAK-STAT pathway leading to Th1 response in experimental allergic encephalomyelitis.
Journal of clinical immunology
Muthian G,Raikwar HP,Johnson C,Rajasingh J,Kalgutkar A,Marnett LJ,Bright JJ
MM700 was used in ELISA to study the mechanism for the effect of COX-2 inhibitors on interleukin 12 signaling
Sun Jan 01 00:00:00 EST 2006
CD40/CD154 interactions are required for the optimal maturation of skin-derived APCs and the induction of helminth-specific IFN-gamma but not IL-4.
Journal of immunology (Baltimore, Md. : 1950)
Hewitson JP,Jenkins GR,Hamblin PA,Mountford AP
MM700 was used in ELISA to study T cell responses in CD154-/- mice treated with radiation-attenuated S. mansoni larvae.
Fri Sep 01 00:00:00 EDT 2006
1,25 Dihydroxyvitamin-D3 modulates JAK-STAT pathway in IL-12/IFNgamma axis leading to Th1 response in experimental allergic encephalomyelitis.
Journal of neuroscience research
Muthian G,Raikwar HP,Rajasingh J,Bright JJ
MM700 was used in ELISA to study the effect of vitamin D on the JAK-STAT pathway and in experimental allergic encephalomyelitis
Mon May 15 00:00:00 EDT 2006
1,25 Dihydroxyvitamin-D3 modulates JAK-STAT pathway in IL-12/IFNgamma axis leading to Th1 response in experimental allergic encephalomyelitis.
Journal of neuroscience research
Muthian G,Raikwar HP,Rajasingh J,Bright JJ
MM700 was used in ELISA to study the effect of vitamin D on the JAK-STAT pathway and in experimental allergic encephalomyelitis
Mon May 15 00:00:00 EDT 2006
Gamma interferon, tumor necrosis factor alpha, and nitric oxide synthase 2, key elements of cellular immunity, perform critical protective functions during humoral defense against lethal pulmonary Yersinia pestis infection.
Infection and immunity
Parent MA,Wilhelm LB,Kummer LW,Szaba FM,Mullarky IK,Smiley ST
MM700 was used in blocking/activating experiment to study the protective functions of inteferon gamma, tumor necrosis factor alpha, and NOS2 during humoral defense against lethal pulmonary Y. pestis infection
Thu Jun 01 00:00:00 EDT 2006
PPARgamma antagonists reverse the inhibition of neural antigen-specific Th1 response and experimental allergic encephalomyelitis by Ciglitazone and 15-deoxy-Delta12,14-prostaglandin J2.
Journal of neuroimmunology
Raikwar HP,Muthian G,Rajasingh J,Johnson CN,Bright JJ
MM700 was used in ELISA to study the effects of PPAR gamma antagonists on the physiological response upon ciglitazone and 15-deoxy-Delta12,14-prostaglandin J2
Fri Sep 01 00:00:00 EDT 2006
Setaria digitata secreted filarial lipids modulate IL-12 signaling through JAK-STAT pathway leading to the development of Th1 response.
Experimental parasitology
Muthian G,Pradeep CG,Sargapradeep K,Kaleysaraj R,Bright JJ
MM700 was used in ELISA to study the mechanism for the effect of filarial lipids on interleukin 12 signaling
Wed Nov 01 00:00:00 EST 2006
Differential regulation of virus-specific T-cell effector functions following activation by peptide or innate cytokines.
Blood
Beadling C,Slifka MK
MM700 was used in flow cytometry to investigate how antiviral T cells incorporate multiple signals from their local microenvironment to regulate cytokine production
Tue Feb 01 00:00:00 EST 2005
Listeriolysin O, a cytolysin derived from Listeria monocytogenes, inhibits generation of ovalbumin-specific Th2 immune response by skewing maturation of antigen-specific T cells into Th1 cells.
Clinical and experimental immunology
Yamamoto K,Kawamura I,Tominaga T,Nomura T,Kohda C,Ito J,Mitsuyama M
MM700 was used in ELISA to study the role of Listeriolysin O in skewing maturation of antigen-specific T cells into Th1 cells
Tue Nov 01 00:00:00 EST 2005
Tracking antigen-specific CD8 T lymphocytes in the lungs of mice vaccinated with the Mtb72F polyprotein.
Infection and immunity
Irwin SM,Izzo AA,Dow SW,Skeiky YA,Reed SG,Alderson MR,Orme IM
MM700 was used in flow cytometry to evaluate the tuberculosis vaccine candidate Mtb72F
Thu Sep 01 00:00:00 EDT 2005
Independent protective effects for tumor necrosis factor and lymphotoxin alpha in the host response to Listeria monocytogenes infection.
Infection and immunity
Roach DR,Briscoe H,Saunders BM,Britton WJ
MM700 was used in ELISA to investigate the roles of tumor necrosis factor and lymphotoxin in host resistance to Listeria monocytogenes infection
Mon Aug 01 00:00:00 EDT 2005
Hematopoietic stem cell dose correlates with the speed of immune reconstitution after stem cell transplantation.
Blood
Chen BJ,Cui X,Sempowski GD,Domen J,Chao NJ
MM700 was used in flow cytometry to test if higher numbers of hematopoietic stem cells correlate with the speed of immune reconstitution in a congenic transplantation mouse model
Tue Jun 01 00:00:00 EDT 2004
Quercetin, a flavonoid phytoestrogen, ameliorates experimental allergic encephalomyelitis by blocking IL-12 signaling through JAK-STAT pathway in T lymphocyte.
Journal of clinical immunology
Muthian G,Bright JJ
MM700 was used in ELISA to study the effect of quercetin on interleukin 12 signaling and experimental allergic encephalomyelitis
Wed Sep 01 00:00:00 EDT 2004
Programmed death-1-programmed death-L1 interaction is essential for induction of regulatory cells by intratracheal delivery of alloantigen.
Transplantation
Aramaki O,Shirasugi N,Takayama T,Shimazu M,Kitajima M,Ikeda Y,Azuma M,Okumura K,Yagita H,Niimi M
MM700 was used in ELISA to determine the roles of PD-1 and its ligands in the induction of regulatory cells by intratracheal delivery of alloantigen
Thu Jan 15 00:00:00 EST 2004
Trypanosoma cruzi: the expansion of NK, T, and NKT cells in the experimental infection.
Experimental parasitology
Antúnez MI,Cardoni RL
MM700 was used in ELISA to investigate the expansion of natural killer, T, and natural killer T cells in the experimental infection
Wed Jul 07 00:00:00 EDT 2004
Activation of dendritic cells and induction of T cell responses by HPV 16 L1/E7 chimeric virus-like particles are enhanced by CpG ODN or sorbitol.
Antiviral therapy
Freyschmidt EJ,Alonso A,Hartmann G,Gissmann L
MM700 was used in flow cytometry to study the interaction of human papillomavirus 16 L1/E7 chimeric virus-like particles with mouse bone marrow-derived dendritic cells activated with different immune adjuvants
Sun Aug 01 00:00:00 EDT 2004
Impaired T cell death and lupus-like autoimmunity in T cell-specific adapter protein-deficient mice.
The Journal of experimental medicine
Drappa J,Kamen LA,Chan E,Georgiev M,Ashany D,Marti F,King PD
MM700 was used in flow cytometry to report that T cell-specific adaptor protein-deficient mice develop lupus-like autoimmune disease.
Mon Sep 01 00:00:00 EDT 2003
The combination of plasmid interleukin-12 with a single DNA vaccine is more effective than Mycobacterium bovis (bacille Calmette-Guèrin) in protecting against systemic Mycobacterim avium infection.
Immunology
Martin E,Kamath AT,Briscoe H,Britton WJ
MM700 was used in ELISA to study the protection against systemic Mycobacterim avium infection by plasmid interleukin-12 combined with a single DNA vaccine
Sun Jun 01 00:00:00 EDT 2003
Peroxisome proliferator-activated receptor-gamma-deficient heterozygous mice develop an exacerbated neural antigen-induced Th1 response and experimental allergic encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950)
Natarajan C,Muthian G,Barak Y,Evans RM,Bright JJ
MM700 was used in ELISA to investigate the dysfunction of immune system in PPARgamma deficient heterozygous mice
Mon Dec 01 00:00:00 EST 2003
IL-10 regulates early IL-12-mediated immune responses induced by the radiation-attenuated schistosome vaccine.
International immunology
Hogg KG,Kumkate S,Mountford AP
MM700 was used in flow cytometry to investigate how IL-10 regulates IL-12 production in skin treated with radiation-attenuated schistosomes.
Mon Dec 01 00:00:00 EST 2003
Studies on the generation and maintenance of mucosal cytotoxic T lymphocytes against human immunodeficiency virus type 1 Gag in mice.
AIDS research and human retroviruses
Yoshizawa I,Mizuochi T,Ogata A,Murakami M,Yagita H,Takahashi Y,Mizuochi T,Takemori T,Tsunetsugu-Yokota Y
MM700 was used in ELISA to investigate the method of the mucosal immunity induction against HIV-1 in mice
Sun Jun 01 00:00:00 EDT 2003
Cancer immunotherapy with interleukin 12 and granulocyte-macrophage colony-stimulating factor-encapsulated microspheres: coinduction of innate and adaptive antitumor immunity and cure of disseminated disease.
Cancer research
Hill HC,Conway TF,Sabel MS,Jong YS,Mathiowitz E,Bankert RB,Egilmez NK
MM700 was used in ELISA to study the role of interleukin 12 and granulocyte macrophage colony-stimulating factor microspheres in both innate and adaptive antitumor immune responses
Sun Dec 15 00:00:00 EST 2002
TNF regulates chemokine induction essential for cell recruitment, granuloma formation, and clearance of mycobacterial infection.
Journal of immunology (Baltimore, Md. : 1950)
Roach DR,Bean AG,Demangel C,France MP,Briscoe H,Britton WJ
MM700 was used in ELISA to investigate the important roles of tumor necrosis factor in host resistance to mycobacterial infection
Wed May 01 00:00:00 EDT 2002
Curcumin inhibits experimental allergic encephalomyelitis by blocking IL-12 signaling through Janus kinase-STAT pathway in T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950)
Natarajan C,Bright JJ
MM700 was used in ELISA to study the mechenism for the inhibition of experimental allergic encephalomyeliti by curcumin
Sat Jun 15 00:00:00 EDT 2002
Vaccination with recombinant alphavirus or immune-stimulating complex antigen against respiratory syncytial virus.
Journal of immunology (Baltimore, Md. : 1950)
Chen M,Hu KF,Rozell B,Orvell C,Morein B,Liljeström P
MM700 was used in ELISA to study the vaccination against respiratory syncytial virus
Sun Sep 15 00:00:00 EDT 2002
Peroxisome proliferator-activated receptor-gamma agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation.
Genes and immunity
Natarajan C,Bright JJ
MM700 was used in an ELISA assay to identify that peroxisome proliferator-activated receptor-gamma agonists regulate central nervous system inflammation and demyelination by inhibiting IL-12 production, IL-12 signalling and Th1 differentiation in experimental allergic encephalomyelitis.
Mon Apr 01 00:00:00 EST 2002
Candida albicans infection enhances immunosuppression induced by cyclophosphamide by selective priming of suppressive myeloid progenitors for NO production.
Cellular immunology
Angulo I,Jiménez-Díaz MB,García-Bustos JF,Gargallo D,de las Heras FG,Muñoz-Fernández MA,Fresno M
MM700 was used in flow cytometry to investigate the effect of Candida albicans infection on cyclophosphamide-induced immunosuppression
Wed Feb 05 00:00:00 EST 2003
Essential role of interleukin-12 (IL-12) and IL-18 for gamma interferon production induced by listeriolysin O in mouse spleen cells.
Infection and immunity
Nomura T,Kawamura I,Tsuchiya K,Kohda C,Baba H,Ito Y,Kimoto T,Watanabe I,Mitsuyama M
MM700 was used in ELISA to study the role of macrophage-derived cytokines in the induction of mouse spleen cell IFN-gamma production by listeriolysin O
Fri Mar 01 00:00:00 EST 2002
Old mice express a transient early resistance to pulmonary tuberculosis that is mediated by CD8 T cells.
Infection and immunity
Turner J,Frank AA,Orme IM
MM700 was used in flow cytometry to elucidate the capacity of old mice to control an infection with Mycobacterium tuberculosis.
Thu Aug 01 00:00:00 EDT 2002
Coexpression of interleukin-12 chains by a self-splicing vector increases the protective cellular immune response of DNA and Mycobacterium bovis BCG vaccines against Mycobacterium tuberculosis.
Infection and immunity
Palendira U,Kamath AT,Feng CG,Martin E,Chaplin PJ,Triccas JA,Britton WJ
MM700 was used in ELISA to investigate the effect of coexpression of both interleukin 12 chains on the protection against Mycobacterium tuberculosis infection
Mon Apr 01 00:00:00 EST 2002
The Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxododecanoyl)homoserine lactone contributes to virulence and induces inflammation in vivo.
Journal of bacteriology
Smith RS,Harris SG,Phipps R,Iglewski B
MM700 was used in ELISA to investigate the effect of 3O-C12-HSL for inflammation induction in mice
Fri Feb 01 00:00:00 EST 2002
CD28-independent induction of experimental autoimmune encephalomyelitis.
The Journal of clinical investigation
Chitnis T,Najafian N,Abdallah KA,Dong V,Yagita H,Sayegh MH,Khoury SJ
MM700 was used in ELISA to investigate the pathogenesis of experimental autoimmune encephalomyelitis
Thu Mar 01 00:00:00 EST 2001
Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis.
The Journal of clinical investigation
Chitnis T,Najafian N,Benou C,Salama AD,Grusby MJ,Sayegh MH,Khoury SJ
MM700 was used in ELISA to investigate the role of targeted disruption of STAT4 and STAT6
Sat Sep 01 00:00:00 EDT 2001
A light, nontoxic interleukin 12 protocol inhibits HER-2/neu mammary carcinogenesis in BALB/c transgenic mice with established hyperplasia.
Cancer research
Cifaldi L,Quaglino E,Di Carlo E,Musiani P,Spadaro M,Lollini PL,Wolf S,Boggio K,Forni G,Cavallo F
MM700 was used in ELISA to investigate the therapeutic effect of interleukin 12 administration on HER-2/neu mammary carcinogenesis
Sun Apr 01 00:00:00 EST 2001
CD28 costimulation is required not only to induce IL-12 receptor but also to render janus kinases/STAT4 responsive to IL-12 stimulation in TCR-triggered T cells.
European journal of immunology
Park WR,Park CS,Tomura M,Ahn HJ,Nakahira Y,Iwasaki M,Gao P,Abe R,Hamaoka T,Fujiwara H
MM700 was used in ELISA to investigate the effect of CD28 for the T cell response to interleukin 12 induced by T cell receptor stimulation
Tue May 01 00:00:00 EDT 2001
Immune response induced by airway sensitization after influenza A virus infection depends on timing of antigen exposure in mice.
Journal of virology
Yamamoto N,Suzuki S,Suzuki Y,Shirai A,Nakazawa M,Suzuki M,Takamasu T,Nagashima Y,Minami M,Ishigatsubo Y
MM700 was used in ELISA to characterize the airway immune response after influenza A virus infection
Mon Jan 01 00:00:00 EST 2001
Positive regulatory role of IL-12 in macrophages and modulation by IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950)
Grohmann U,Belladonna ML,Vacca C,Bianchi R,Fallarino F,Orabona C,Fioretti MC,Puccetti P
MM700 was used in blocking/activating experiment to study the role of interleukin 12 in macrophage
Sun Jul 01 00:00:00 EDT 2001
DNA encoding a single mycobacterial antigen protects against leprosy infection.
Vaccine
Martin E,Roche PW,Triccas JA,Britton WJ
MM700 was used in ELISA to investigate the effect of DNA encoding a single mycobacterial antigen for leprosy infection
Mon Jan 08 00:00:00 EST 2001
Nitric oxide-producing CD11b(+)Ly-6G(Gr-1)(+)CD31(ER-MP12)(+) cells in the spleen of cyclophosphamide-treated mice: implications for T-cell responses in immunosuppressed mice.
Blood
Angulo I,de las Heras FG,García-Bustos JF,Gargallo D,Muñoz-Fernández MA,Fresno M
MM700 was used in blocking/activating experiment to investigate the mechanism for cyclophosphamide-induced immunosuppression
Sat Jan 01 00:00:00 EST 2000
Role of passive T-cell death in chronic experimental autoimmune encephalomyelitis.
The Journal of clinical investigation
Issazadeh S,Abdallah K,Chitnis T,Chandraker A,Wells AD,Turka LA,Sayegh MH,Khoury SJ
MM700 was used in ELISA to study the mechanism for T-cell loss in chronic experimental autoimmune encephalomyelitis
Sat Apr 01 00:00:00 EST 2000
Viral escape by selection of cytotoxic T cell-resistant variants in influenza A virus pneumonia.
The Journal of experimental medicine
Price GE,Ou R,Jiang H,Huang L,Moskophidis D
MM700 was used in flow cytometry to study the importance of CD8(+) cytotoxic T lymphocytes during influenza A viral persistence.
Mon Jun 05 00:00:00 EDT 2000
Partially TAP-independent protection against Listeria monocytogenes by H2-M3-restricted CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950)
Rolph MS,Kaufmann SH
MM700 was used in ELISA to study the immune responses against Listeria monocytogenes
Sun Oct 15 00:00:00 EDT 2000
Prevention of graft-versus-host disease by a novel immunosuppressant, PG490-88, through inhibition of alloreactive T cell expansion.
Transplantation
Chen BJ,Liu C,Cui X,Fidler JM,Chao NJ
MM700 was used in flow cytometry to discuss PG490-88.
Mon Nov 27 00:00:00 EST 2000
Differential IL-12 responsiveness of T cells but not of NK cells from tumor-bearing mice in IL-12-responsive versus -unresponsive tumor models.
International immunology
Iwasaki M,Yu WG,Uekusa Y,Nakajima C,Yang YF,Gao P,Wijesuriya R,Fujiwara H,Hamaoka T
MM700 was used in ELISA to investigate the mechanism for the anti-tumor effect of interleukin 12 administration
Mon May 01 00:00:00 EDT 2000
Tumor vaccination that enhances antitumor T-cell responses does not inhibit the growth of established tumors even in combination with interleukin-12 treatment: the importance of inducing intratumoral T-cell migration.
Journal of immunotherapy (Hagerstown, Md. : 1997)
Gao P,Uekusa Y,Nakajima C,Iwasaki M,Nakahira M,Yang YF,Ono S,Tsujimura T,Fujiwara H,Hamaoka T
MM700 was used in ELISA to investigate the effects of tumor vaccination on tumor inhibition
Thu Mar 29 00:00:00 EST 2001
IL-12 and IFN-gamma production, and NK cell activity, in acute and chronic experimental Trypanosoma cruzi infections.
Immunology letters
Antúnez MI,Cardoni RL
MM700 was used in ELISA to study NK cell activity and IL-12 and IFN-gamma production in acute and chronic experimental Trypanosoma cruzi infections
Tue Feb 01 00:00:00 EST 2000
Mycobacterium bovis bacillus calmette-guérin induces protective immunity against infection by Plasmodium yoelii at blood-stage depending on shifting immunity toward Th1 type and inducing protective IgG2a after the parasite infection.
Vaccine
Matsumoto S,Yukitake H,Kanbara H,Yamada H,Kitamura A,Yamada T
MM700 was used in blocking/activating experiment to investigate the immune responses to Mycobacterium bovis bacillus calmette-guerin
Wed Nov 22 00:00:00 EST 2000
Protection against virulent Mycobacterium avium infection following DNA vaccination with the 35-kilodalton antigen is accompanied by induction of gamma interferon-secreting CD4(+) T cells.
Infection and immunity
Martin E,Kamath AT,Triccas JA,Britton WJ
MM700 was used in ELISA to investigate the effect of DNA vaccination on Mycobacterium avium infection and its mechanism
Thu Jun 01 00:00:00 EDT 2000
The absence of interleukin 1 receptor-related T1/ST2 does not affect T helper cell type 2 development and its effector function.
The Journal of experimental medicine
Hoshino K,Kashiwamura S,Kuribayashi K,Kodama T,Tsujimura T,Nakanishi K,Matsuyama T,Takeda K,Akira S
MM700 was used in blocking/activating experiment to study the Th2 cell differentiation
Mon Nov 15 00:00:00 EST 1999
Co-immunization with DNA vaccines expressing granulocyte-macrophage colony-stimulating factor and mycobacterial secreted proteins enhances T-cell immunity, but not protective efficacy against Mycobacterium tuberculosis.
Immunology
Kamath AT,Hanke T,Briscoe H,Britton WJ
MM700 was used in ELISA to investigate the effects of specific cytokines on immune response against Mycobacterium tuberculosis
Thu Apr 01 00:00:00 EST 1999
A novel function of Valpha14+CD4+NKT cells: stimulation of IL-12 production by antigen-presenting cells in the innate immune system.
Journal of immunology (Baltimore, Md. : 1950)
Tomura M,Yu WG,Ahn HJ,Yamashita M,Yang YF,Ono S,Hamaoka T,Kawano T,Taniguchi M,Koezuka Y,Fujiwara H
MM700 was used in ELISA to characterize a new role of Valpha14+CD4+ NKT cells
Thu Jul 01 00:00:00 EDT 1999
Cytokine requirements for production of a novel anti-CD8-resistant CTL population.
Journal of immunology (Baltimore, Md. : 1950)
Lamousé-Smith ES,Dougall DS,McCarthy SA
MM700 was used in flow cytometry to investigate the role of cytokines in the generation of a CTL subpopulation
Fri Oct 15 00:00:00 EDT 1999
Mouse monocyte-derived chemokine is involved in airway hyperreactivity and lung inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Gonzalo JA,Pan Y,Lloyd CM,Jia GQ,Yu G,Dussault B,Powers CA,Proudfoot AE,Coyle AJ,Gearing D,Gutierrez-Ramos JC
MM700 was used in blocking/activating experiment to study the role of mMDC in airway hyperreactivity and lung inflammation
Thu Jul 01 00:00:00 EDT 1999
Structural deficiencies in granuloma formation in TNF gene-targeted mice underlie the heightened susceptibility to aerosol Mycobacterium tuberculosis infection, which is not compensated for by lymphotoxin.
Journal of immunology (Baltimore, Md. : 1950)
Bean AG,Roach DR,Briscoe H,France MP,Korner H,Sedgwick JD,Britton WJ
MM700 was used in ELISA to investigate the important roles of tumor necrosis factor in host susceptibility to Mycobacterium tuberculosis infection
Mon Mar 15 00:00:00 EST 1999
Differential protective efficacy of DNA vaccines expressing secreted proteins of Mycobacterium tuberculosis.
Infection and immunity
Kamath AT,Feng CG,Macdonald M,Briscoe H,Britton WJ
MM700 was used in ELISA to evaluate the different Mycobacterium tuberculosis DNA vaccines
Thu Apr 01 00:00:00 EST 1999
Endogenous myelin basic protein inactivates the high avidity T cell repertoire.
The Journal of experimental medicine
Targoni OS,Lehmann PV
MM700 was used in ELISA to study the effect of myelin basic protein on high avidity T cells
Mon Jun 15 00:00:00 EDT 1998
Cell division regulates the T cell cytokine repertoire, revealing a mechanism underlying immune class regulation.
Proceedings of the National Academy of Sciences of the United States of America
Gett AV,Hodgkin PD
MM700 was used in flow cytometry to report that the number of divisions taken by T cells after activation contributes to their differentiation.
Tue Aug 04 00:00:00 EDT 1998
Immunization of mice with phosphatidylcholine drastically reduces the parasitaemia of subsequent Plasmodium chabaudi chabaudi blood-stage infections.
Immunology
Bordmann G,Rudin W,Favre N
MM700 was used in ELISA to investigate the effect of phosphatidylcholine immunization of mice for the parasitaemia of subsequent Plasmodium chabaudi chabaudi blood-stage infections
Fri May 01 00:00:00 EDT 1998
Cardiac allografts from IL-4 knockout recipients: assessment of transplant arteriosclerosis and peripheral tolerance.
Journal of immunology (Baltimore, Md. : 1950)
Mottram PL,Räisänen-Sokolowski A,Glysing-Jensen T,Stein-Oakley AN,Russell ME
MM700 was used in immunohistochemistry to investigate the role of interleukin 4 in the development of transplant arteriosclerosis
Wed Jul 15 00:00:00 EDT 1998
Topical FK506 suppresses cytokine and costimulatory molecule expression in epidermal and local draining lymph node cells during primary skin immune responses.
Journal of immunology (Baltimore, Md. : 1950)
Homey B,Assmann T,Vohr HW,Ulrich P,Lauerma AI,Ruzicka T,Lehmann P,Schuppe HC
MM700 was used in flow cytometry to investigate the changes of gene expression by FK506 stimulation during primary skin immune responses
Mon Jun 01 00:00:00 EDT 1998
Requirement for distinct Janus kinases and STAT proteins in T cell proliferation versus IFN-gamma production following IL-12 stimulation.
Journal of immunology (Baltimore, Md. : 1950)
Ahn HJ,Tomura M,Yu WG,Iwasaki M,Park WR,Hamaoka T,Fujiwara H
MM700 was used in ELISA to investigate the relationship between interleukin 12, JAK2 and TYK2
Tue Dec 01 00:00:00 EST 1998
Prevention of experimental allergic encephalomyelitis via inhibition of IL-12 signaling and IL-12-mediated Th1 differentiation: an effect of the novel anti-inflammatory drug lisofylline.
Journal of immunology (Baltimore, Md. : 1950)
Bright JJ,Du C,Coon M,Sriram S,Klaus SJ
MM700 was used in ELISA to investigate the effect of anti-inflammatory drug lisofylline on cytokine signaling and T cell differentiation
Tue Dec 15 00:00:00 EST 1998
Differential capacities of CD4+, CD8+, and CD4-CD8- T cell subsets to express IL-18 receptor and produce IFN-gamma in response to IL-18.
Journal of immunology (Baltimore, Md. : 1950)
Tomura M,Maruo S,Mu J,Zhou XY,Ahn HJ,Hamaoka T,Okamura H,Nakanishi K,Clark S,Kurimoto M,Fujiwara H
MM700 was used in ELISA to investigate the various responses of T cell subsets against interleukin 18 stimulation
Wed Apr 15 00:00:00 EDT 1998
A critical role for IL-18 in the proliferation and activation of NK1.1+ CD3- cells.
Journal of immunology (Baltimore, Md. : 1950)
Tomura M,Zhou XY,Maruo S,Ahn HJ,Hamaoka T,Okamura H,Nakanishi K,Tanimoto T,Kurimoto M,Fujiwara H
MM700 was used in ELISA to investigate the role of interleukin 18 in the regulation of NK1.1+ CD3- cells
Fri May 15 00:00:00 EDT 1998
Heat-killed Listeria monocytogenes as an adjuvant converts established murine Th2-dominated immune responses into Th1-dominated responses.
Journal of immunology (Baltimore, Md. : 1950)
Yeung VP,Gieni RS,Umetsu DT,DeKruyff RH
MM700 was used in blocking/activating experiment to investigate the effect of Listeria monocytogenes on immune responses
Thu Oct 15 00:00:00 EDT 1998
B cell-mediated down-regulation of IFN-gamma and IL-12 production induced during anti-tumor immune responses in the tumor-bearing state.
International immunology
Wijesuriya R,Maruo S,Zou JP,Ogawa M,Umehara K,Yamashita M,Ono S,Fujiwara H,Hamaoka T
MM700 was used in ELISA to investigate the mechanism for the interferon gamma production during antigen presentation
Sat Aug 01 00:00:00 EDT 1998
Expression of IL-12 in CNS and lymphoid organs of mice with experimental allergic encephalitis.
Journal of neuroimmunology
Bright JJ,Famakin BM,Du C,Sriram S
MM700 was used in ELISA to investigate the expression of interleukin 12 in central nervous system and lymphoid organs
Sun Feb 01 00:00:00 EST 1998
Sequential T cell response involved in tumor rejection of sarcoma, Meth A, in syngeneic mice.
Japanese journal of cancer research : Gann
Jiao Y,Fujimoto S
MM700 was used in ELISA to study the mechanism for the Meth A tumor rejection
Mon Jun 01 00:00:00 EDT 1998
A mechanism underlying synergy between IL-12 and IFN-gamma-inducing factor in enhanced production of IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950)
Ahn HJ,Maruo S,Tomura M,Mu J,Hamaoka T,Nakanishi K,Clark S,Kurimoto M,Okamura H,Fujiwara H
MM700 was used in ELISA to investigate the relationship between interleukin 12 and IFN-gamma-inducing factor during interferon gamma production
Mon Sep 01 00:00:00 EDT 1997
The cytokines IL-4, IFN-gamma, and IL-12 regulate the development of subsets of memory effector helper T cells in vitro.
Journal of immunology (Baltimore, Md. : 1950)
Bradley LM,Yoshimoto K,Swain SL
MM700 was used in blocking/activating experiment to study the effect of interleukin 4, interferon gamma, and interleukin 12 on memory effector helper T cells
Tue Aug 15 00:00:00 EDT 1995
A role for nonspecific (cyclosporin A) or specific (monoclonal antibodies to ICAM-1, LFA-1, and IL-10) immunomodulation in the prolongation of skin allografts after antigen-specific pretransplant immunization or transfusion.
Journal of immunology (Baltimore, Md. : 1950)
Gorczynski RM,Wojcik D
MM700 was used in blocking/activating experiment to study the approaches to achieve long-term graft survival in mice
Tue Feb 15 00:00:00 EST 1994
Analysis of IL-2, IL-4, and IFN-gamma-producing cells in situ during immune responses to protein antigens.
Journal of immunology (Baltimore, Md. : 1950)
Bogen SA,Fogelman I,Abbas AK
MM700 was used in immunohistochemistry to investigate the production of interleukin 2 and 4 and interferon gamma in mice immunized with protein antigens
Sat May 15 00:00:00 EDT 1993
Analysis of Th1 and Th2 cells in murine gut-associated tissues. Frequencies of CD4+ and CD8+ T cells that secrete IFN-gamma and IL-5.
Journal of immunology (Baltimore, Md. : 1950)
Taguchi T,McGhee JR,Coffman RL,Beagley KW,Eldridge JH,Takatsu K,Kiyono H
MM700 was used in ELISA to investigate the characteristics of Th1 and Th2 cells in mouse gut-associated tissues
Sun Jul 01 00:00:00 EDT 1990
Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies.
The Journal of experimental medicine
Cherwinski HM,Schumacher JH,Brown KD,Mosmann TR
MM700 was used in ELISA to assess the lymphokine synthesis patterns of a panel of T cell clones
Sun Nov 01 00:00:00 EST 1987
