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IGF2BP2 Antibody (A500-012A) in WB
Detection of human and mouse IGF2BP2 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, Jurkat, TCMK1, and NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Mouse anti-IGF2BP2 monoclonal antibody [1E3.01E5] (Product # A500-012A lot 3) used at 1:1000. Secondary: HRP-conjugated goat anti-mouse IgG (A90-116P). Chemiluminescence with an exposure time of 3 seconds.
产品信息
A500-012A
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
1E3.01E5
抗原
Full length recombinant human protein IGF mRNA-binding protein 2
偶联物
形式
Liquid
浓度
40 µg/mL
纯化类型
Affinity chromatography
保存液
TBS, pH 7.0 to 8.0, with 0.1% BSA
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
靶标信息
IGF2BP2 is a member of the IGF-II mRNA-binding protein (IMP) family. It recruits target transcripts to cytoplasmic protein-RNA complexes. The protein contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Autoantibodies against IGF2BP2 are detected in sera from some patients with hepatocellular carcinoma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Hepatocellular carcinoma autoantigen p62; IGF-II mRNA-binding protein 2; IGF2 mRNA-binding protein 2; insulin-like growth factor 2 mRNA binding protein 2; Insulin-like growth factor 2 mRNA-binding protein 2; insulin-like growth factor 2, binding protein 2; VICKZ family member 2
基因别名: C330012H03Rik; IGF2BP2; IMP-2; IMP2; Neilsen; VICKZ2
UniProt ID: (Human) B3FTN2, (Mouse) Q5SF07
Entrez Gene ID: (Human) 10644, (Mouse) 319765
