Invitrogen

IGFBP-1 Polyclonal Antibody

IGFBP-1 Antibody in Immunocytochemistry (ICC/IF)

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IGFBP-1 Antibody (PA5-78020) in ICC/IF

Immunocytochemistry-Immunofluorescence analysis of IGFBP-1 was performed in HepG2 cells fixed in 4% paraformaldehyde at RT for 15 min. Green: IGFBP-1 Polyclonal Antibody (Product # PA5-78020) diluted at 1:500. Blue: Hoechst 33342 staining.

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产品信息

PA5-78020

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:3,000

免疫细胞化学 (ICC/IF)

1:100-1:1,000

免疫沉淀 (IP)

1:100-1:500

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein encompassing a sequence within the center region of human IGFBP1. The exact sequence is proprietary.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7, with 20% glycerol

内含物

0.025% ProClin 300

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2735950

产品详细信息

Positive Control: HepG2

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: alpha-pregnancy-associated endometrial globulin; amniotic fluid binding protein; Binding protein 25; Binding protein 26; Binding protein 28; binding protein-25; binding protein-26; binding protein-28; growth hormone independent-binding protein; hIGFBP 1; hIGFBP1; IBP 1; IBP-1; IGF BP25; IGF-binding protein 1; IGFBP; IGFBP 1; IGFBP-1; Insulin like growth factor binding protein; insulin-like growth factor binding protein 1; Insulin-like growth factor-binding protein 1; Placental protein 12; PP 12; PP12

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基因别名: AFBP; hIGFBP-1; IBP1; IGF-BP25; IGFBP1; PP12

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UniProt ID: (Human) P08833

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Entrez Gene ID: (Human) 3484

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功能

receptor binding insulin-like growth factor binding insulin-like growth factor I binding insulin-like growth factor II binding protease inhibitor

参与通路

signal transduction insulin receptor signaling pathway positive regulation of cell growth PERK-mediated unfolded protein response tissue regeneration regulation of insulin-like growth factor receptor signaling pathway cellular protein metabolic process negative regulation of canonical Wnt signaling pathway