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Peptide sequence: RALERLAASQ SRTHEDLYII PIPNCDRNGN FHPKQCHPAL DGQRGKCWCV
Sequence homology: Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%
This gene is a member of the insulin-like growth factor binding protein family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Band 3A; differentially expressed in B16F10 2; IBP-4; IGF-binding protein 4; IGFBP; Insulin like growth factor binding protein; insulin-like growth factor binding protein 4; Insulin-like growth factor-binding protein 4
基因别名: AI875747; BP-4; Deb2; HT29-IGFBP; IBP4; IGFBP-4; IGFBP4
UniProt ID: (Human) P22692, (Mouse) P47879
Entrez Gene ID: (Human) 3487, (Mouse) 16010
分子生物学功能:
protease inhibitor