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IGFBP6 Antibody (PA5-115397) in ICC/IF
Immunocytochemistry analysis of IGFBP6 in A549 cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115397). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Green) and DAPI.
产品信息
PA5-115397
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human IGFBP6(Accession P24592), corresponding to amino acid residues R108-T158.
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2900033
产品详细信息
Antibody detects endogenous levels of total IGFBP6.
靶标信息
IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. IGF-BP6, which specifically inhibits IGF-II actions, is produced by bone cells and is the major IGF-BP present in cerebrospinal fluid. IGF-BP6 has been shown to inhibit IGF-II-dependent cancers such as neuroblastoma, colon cancer and rhabdomyosarcoma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: IBP-6; IGF binding protein 6; IGF-binding protein 6; IGFBP; IGFBP-6; Insulin like growth factor binding protein; insulin-like growth factor binding protein 6; Insulin-like growth factor-binding protein 6
基因别名: IBP6; IGF-BP6; Igfbp-6; IGFBP6; RBP6A
UniProt ID: (Human) P24592, (Rat) P35572
Entrez Gene ID: (Human) 3489, (Rat) 25641
