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Proteintech

IKBKG Polyclonal Antibody

29 篇参考文献

查看其他23个IKK gamma抗体

说明书

实验方案

技术支持

货号 18474-1-AP

此产品在中国无法购买

150 µL

说明书

实验方案

技术支持

抗体检测数据 (8)

Application

IKBKG Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 8

IKBKG Antibody (18474-1-AP) in ICC/IF

Immunofluorescent analysis of HeLa cells using 18474-1-AP (IKBKG antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

IKBKG Antibody in Immunohistochemistry (Paraffin) (IHC (P))

IKBKG Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))

Product Image Gallery

产品信息

18474-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

查看25篇已发表文章 25篇已发表文章

免疫组化（石蜡） (IHC (P))

1:20-1:200

免疫组织化学（多聚甲醛固定） (IHC (PFA))

1:20-1:200

免疫细胞化学 (ICC/IF)

1:20-1:200

查看1篇已发表文章 1篇已发表文章

免疫沉淀 (IP)

查看2篇已发表文章 2篇已发表文章

不适用 (N/A)

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

IKBKG Fusion Protein Ag13358 (120-419 aa encoded by BC012114)

查看免疫原

偶联物

Unconjugated

形式

Liquid

浓度

0.19 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: QALREVEHL KRCQQQMAED KASVKAQVTS LLGELQESQS RLEAATKECQ ALEGRARAAS EQARQLESER EALQQQHSVQ VDQLRMQGQS VEAALRMERQ AASEEKRKLA QLQVAYHQLF QEYDNHIKSS VVGSERKRGM QLEDLKQQLQ QAEEALVAKQ EVIDKLKEEA EQHKIVMETV PVLKAQADIY KADFQAERQA REKLAEKKEL LQEQLEQLQR EYSKLKASCQ ESARIEDMRK RHVEVSQAPL PPAPAYLSSP LALPSQRRSP PEEPPDFCCP KCQYQAPDMD TLQIHVMECI E (120-419 aa encoded by BC012114)

靶标信息

IKK gamma is the regulatory subunit of the inhibitor of the kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: FIP-3; gikk; I-kappa-B kinase gamma; I-kappa-B kinase subunit gamma; ikB kinase subunit gamma; IkB kinase-associated protein 1; IKK-gamma; IKK3; IKKAP1; IKKG; incontinentia pigmenti; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma; inhibitor of kappaB kinase gamma; Inhibitor of nuclear factor kappa-B kinase subunit gamma; mF; mFIP-3; NEMO; NF-kappa B essential modulator; NF-kappa-B essential modifier; NF-kappa-B essential modulator; OTTHUMP00000207079; OTTHUMP00000212188

基因别名: 1110037D23Rik; AI848108; AI851264; AMCBX1; AW124339; FIP-3; FIP3; Fip3p; IKBKG; IKK-gamma; IKK[g]; IKKAP1; IKKG; IMD33; IP; IP1; IP2; IPD2; NEMO; ZC2HC9

UniProt ID: (Human) Q9Y6K9, (Mouse) O88522, (Rat) Q6TMG5

Entrez Gene ID: (Human) 8517, (Mouse) 16151, (Rat) 309295

功能

signal transducer activity protein binding protein domain specific binding ubiquitin protein ligase binding protein homodimerization activity peroxisome proliferator activated receptor binding metal ion binding protein heterodimerization activity K63-linked polyubiquitin binding linear polyubiquitin binding

参与通路

B cell homeostasis transcription, DNA-templated regulation of transcription, DNA-templated cellular response to DNA damage stimulus activation of NF-kappaB-inducing kinase activity positive regulation of gene expression positive regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of transcription from RNA polymerase II promoter positive regulation of NF-kappaB transcription factor activity establishment of vesicle localization negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway activation of MAPK activity stimulatory C-type lectin receptor signaling pathway apoptotic process inflammatory response immune response I-kappaB kinase/NF-kappaB signaling JNK cascade response to virus regulation of tumor necrosis factor-mediated signaling pathway TRIF-dependent toll-like receptor signaling pathway Fc-epsilon receptor signaling pathway innate immune response T cell receptor signaling pathway stress-activated MAPK cascade nucleotide-binding oligomerization domain containing signaling pathway negative regulation of neuron death NF-kappaB import into nucleus

IKBKG Polyclonal Antibody

IKBKG Antibody (18474-1-AP) in ICC/IF

产品信息

18474-1-AP

免疫印迹 (WB)

免疫组化（石蜡） (IHC (P))

免疫组织化学（多聚甲醛固定） (IHC (PFA))

免疫细胞化学 (ICC/IF)

免疫沉淀 (IP)

不适用 (N/A)

种属反应

已发表种属

宿主/亚型

分类

类型

抗原

偶联物

形式

浓度

纯化类型

保存液

内含物

保存条件

运输条件

产品详细信息

靶标信息

生物信息学

性能保障

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