Product References
HC067047 as a potent TRPV4 inhibitor repairs endotoxemia colonic injury.
International immunopharmacology
Chen L,Mao M,Liu D,Liu W,Wang Y,Xie L,Deng Y,Lin Y,Xu Y,Zhong X,Cao W
Wed Mar 01 00:00:00 EST 2023
Effects of a Macroporous Resin Extract of Dendrobium officinale Leaves in Rats with Hyperuricemia Induced by Anthropomorphic Unhealthy Lifestyle.
Evidence-based complementary and alternative medicine : eCAM
Li LZ,Wang XM,Feng XJ,Liu K,Li B,Zhu LJ,Xu WF,Zheng X,Dong YJ,He XL,Guan HR,Ding YY,Wu HS,Zhou CJ,Ye SY,Zhang BB,Lv GY,Chen SH
Tue Jan 17 00:00:00 EST 2023
Heat-killed Lactobacillus murinus confers neuroprotection against dopamine neuronal loss by targeting NLRP3 inflammasome.
Bioengineering & translational medicine
Fan HX,Sheng S,Li DD,Li JJ,Wang GQ,Zhang F
Wed Mar 01 00:00:00 EST 2023
Lysosomal control of senescence and inflammation through cholesterol partitioning.
Nature metabolism
Roh K,Noh J,Kim Y,Jang Y,Kim J,Choi H,Lee Y,Ji M,Kang D,Kim MS,Paik MJ,Chung J,Kim JH,Kang C
Wed Mar 01 00:00:00 EST 2023
Aryl hydrocarbon receptor dependent anti-inflammation and neuroprotective effects of tryptophan metabolites on retinal ischemia/reperfusion injury.
Cell death & disease
Yang Y,Wang N,Xu L,Liu Y,Huang L,Gu M,Wu Y,Guo W,Sun H
Wed Feb 08 00:00:00 EST 2023
β-Hydroxybutyric acid upregulated by Suhuang antitussive capsule ameliorates cough variant asthma through GSK3β/AMPK-Nrf2 signal axis.
Journal of ethnopharmacology
Jiang H,Bai Z,Ou Y,Liu H,Si Z,Liu Y,Liu X,Liu X,Zhang Z,Tan N
Wed May 10 00:00:00 EDT 2023
Photobiomodulation treatment inhibits neurotoxic astrocytic polarization and protects neurons in in vitro and in vivo stroke models.
Neurochemistry international
Feng Y,Yang L,Ma X,Huang Z,Zong X,Citadin CT,Lin HW,Zhang Q
Sun Jan 01 00:00:00 EST 2023
C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways.
Journal of applied oral science : revista FOB
Chen Y,Liu Y,Li H,Huna R,Tan X,Li N,Zhang Y,Jiao X,Liu M
Fri Feb 10 00:00:00 EST 2023
DTX3L induced NLRP3 ubiquitination inhibit R28 cell pyroptosis in OGD/R injury.
Biochimica et biophysica acta. Molecular cell research
Zhou Z,Shang L,Zhang Q,Hu X,Huang JF,Xiong K
Wed Mar 01 00:00:00 EST 2023
VX-765 attenuates silica-induced lung inflammatory injury and fibrosis by modulating alveolar macrophages pyroptosis in mice.
Ecotoxicology and environmental safety
Tao H,Zhao H,Mo A,Shao L,Ge D,Liu J,Hu W,Xu K,Ma Q,Wang W,Wang W,Cao H,Mu M,Tao X,Wang J
Sun Jan 01 00:00:00 EST 2023
Protective efficacy of Schizandrin B on ameliorating nephrolithiasis via regulating GSK3β/Nrf2 signaling-mediated ferroptosis in vivo and in vitro.
International immunopharmacology
Dong C,Song C,He Z,Song Q,Song T,Liu J,Xiong Y,Su X,Zhou J,Yang S,Liao W
Sat Apr 01 00:00:00 EDT 2023
Ethanol Extract of Rosa laevigata Michx. Fruit Inhibits Inflammatory Responses through NF-κB/MAPK Signaling Pathways via AMPK Activation in RAW 264.7 Macrophages.
Molecules (Basel, Switzerland)
Wu H,Lin T,Chen Y,Chen F,Zhang S,Pang H,Huang L,Yu C,Wang G,Wu C
Mon Mar 20 00:00:00 EDT 2023
Apoptosis or Antiapoptosis? Interrupted Regulated Cell Death of Host Cells by Ascovirus Infection In Vitro.
mBio
Yu H,Li JR,Xiao HY,Cao SK,Chen B,Li N,Chen G,Huang GH
Tue Feb 28 00:00:00 EST 2023
Role of the Peli1-RIPK1 Signaling Axis in Methamphetamine-Induced Neuroinflammation.
ACS chemical neuroscience
Xu W,Yang T,Lou X,Chen J,Wang X,Hu M,An D,Gao R,Wang J,Chen X
Wed Mar 01 00:00:00 EST 2023
Hydrogen Sulfide Inhibited Sympathetic Activation in D-Galactose-Induced Aging Rats by Upregulating Klotho and Inhibiting Inflammation in the Paraventricular Nucleus.
Biomedicines
Yu H,Yu Q,Mi Y,Wang P,Jin S,Xiao L,Guo Q,Wu Y
Wed Feb 15 00:00:00 EST 2023
Protective effecs of baicalin magnesium on non-alcoholic steatohepatitis rats are based on inhibiting NLRP3/Caspase-1/IL-1β signaling pathway.
BMC complementary medicine and therapies
Guan X,Shen S,Liu J,Song H,Chang J,Mao X,Song J,Zhang L,Liu C
Mon Mar 06 00:00:00 EST 2023
Amelioration of central neurodegeneration by docosahexaenoic acid in trigeminal neuralgia rats through the regulation of central neuroinflammation.
International immunopharmacology
Mu G,Ren C,Zhang Y,Lu B,Feng J,Wu D,Xu X,Ou C
Sun Jan 01 00:00:00 EST 2023
HC067047 Ameliorates Sepsis-associated Encephalopathy by Suppressing Endoplasmic Reticulum Stress and Oxidative Stress-Induced Pyroptosis in the Hippocampi of Mice.
Neuroscience
Zhong X,Wang Y,Liu D,Liang Y,Liu W,Huang Y,Xie L,Cao W,Xu Y,Chen L
Mon May 01 00:00:00 EDT 2023
Inhibition of PINK1-Mediated Mitophagy Contributes to Postoperative Cognitive Dysfunction through Activation of Caspase-3/GSDME-Dependent Pyroptosis.
ACS chemical neuroscience
Wang W,Zhao B,Gao W,Song W,Hou J,Zhang L,Xia Z
Wed Apr 05 00:00:00 EDT 2023
Sphingosine-1-Phosphate Receptor 4 Attenuates Neutrophilic Airway Inflammation in Experimental Asthma via Repressing Proinflammatory Macrophage Activation.
International journal of biological sciences
Wang S,Tian Z,Lu Y,Huang Z,Fan Y,Li B,Zheng H,Wu X,Wang M,Zhao J,Xie J
Mon Apr 17 00:00:00 EDT 2023
Sphingosine-1-Phosphate Receptor 4 Attenuates Neutrophilic Airway Inflammation in Experimental Asthma via Repressing Proinflammatory Macrophage Activation.
International journal of biological sciences
Wang S,Tian Z,Lu Y,Huang Z,Fan Y,Li B,Zheng H,Wu X,Wang M,Zhao J,Xie J
Mon Apr 17 00:00:00 EDT 2023
Rat tight junction proteins are disrupted after subchronic exposure to okadaic acid.
Environmental science and pollution research international
Huang L,Liu B,Yu XW,Pan GQ,Xu JY,Yan D,Wang YL,Guo QN
Mon May 01 00:00:00 EDT 2023
Protective effects of baicalin against L-glutamate-induced oxidative damage in HT-22 cells by inhibiting NLRP3 inflammasome activation via Nrf2/HO-1 signaling.
Iranian journal of basic medical sciences
Li J,Wang G,Zhang Y,Fan X,Yao M
Wed Mar 01 00:00:00 EST 2023
Cartilage Damage Pathological Characteristics of Diabetic Neuropathic Osteoarthropathy.
Analytical cellular pathology (Amsterdam)
Liu PL,Diao JY,Wang Q,Liu H,Zhang Y,Liang JQ,Zhang F,Liang XJ,Zhao HM
Fri May 19 00:00:00 EDT 2023
Cell-Permeable PROTAC Degraders against KEAP1 Efficiently Suppress Hepatic Stellate Cell Activation through the Antioxidant and Anti-Inflammatory Pathway.
ACS pharmacology & translational science
Wang F,Zhan Y,Li M,Wang L,Zheng A,Liu C,Wang H,Wang T
Fri Jan 13 00:00:00 EST 2023
Extracellular vesicles released from macrophages modulates interleukin-1β in astrocytic and neuronal cells.
Scientific reports
Kodidela S,Sinha N,Kumar A,Zhou L,Godse S,Kumar S
Tue Feb 21 00:00:00 EST 2023
Silencing of FAM111B inhibits tumor growth and promotes apoptosis by decreasing AKT activity in ovarian cancer.
Experimental biology and medicine (Maywood, N.J.)
Wang W,Gu Y,Ni H,Quan Q,Guo L
Thu Jun 01 00:00:00 EDT 2023
Minocycline, a classic antibiotic, exerts psychotropic effects by normalizing microglial neuroinflammation-evoked tryptophan-kynurenine pathway dysregulation in chronically stressed male mice.
Brain, behavior, and immunity
Cheng D,Qin ZS,Zheng Y,Xie JY,Liang SS,Zhang JL,Feng YB,Zhang ZJ
Sun Jan 01 00:00:00 EST 2023
Metformin Attenuates the Inflammatory Response via the Regulation of Synovial M1 Macrophage in Osteoarthritis.
International journal of molecular sciences
Zheng M,Zhu Y,Wei K,Pu H,Peng R,Xiao J,Liu C,Sun X
Fri Mar 10 00:00:00 EST 2023
Investigation of He's Yang Chao recipe against oxidative stress-related mitophagy and pyroptosis to improve ovarian function.
Frontiers in endocrinology
Miao C,Zhao Y,Chen Y,Wang R,Ren N,Chen B,Dong P,Zhang Q
Tue Feb 14 00:00:00 EST 2023
Exosomes Derived from AT2R-Overexpressing BMSC Prevent Restenosis After Carotid Artery Injury by Attenuating the Injury-Induced Neointimal Hyperplasia.
Journal of cardiovascular translational research
Zou X,Liao Y,Liu Z,Xu X,Sun W,Qin H,Wang H,Liu J,Jing T
Wed Feb 01 00:00:00 EST 2023
Osthole: A potential AMPK agonist that inhibits NLRP3 inflammasome activation by regulating mitochondrial homeostasis for combating rheumatoid arthritis.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Jiang X,Lu Z,Zhang Q,Yu J,Han D,Liu J,Li P,Li F
Wed Feb 01 00:00:00 EST 2023
4-Octyl itaconate attenuates LPS-induced acute kidney injury by activating Nrf2 and inhibiting STAT3 signaling.
Molecular medicine (Cambridge, Mass.)
Xu L,Cai J,Li C,Yang M,Duan T,Zhao Q,Xi Y,Sun L,He L,Tang C,Sun L
Mon Apr 24 00:00:00 EDT 2023
Unresolved Excess Accumulation of Myelin-Derived Cholesterol Contributes to Scar Formation after Spinal Cord Injury.
Research (Washington, D.C.)
Zheng B,He Y,Yin S,Zhu X,Zhao Q,Yang H,Wang Z,Zhu R,Cheng L
Thu May 25 00:00:00 EDT 2023
PM2.5 induce myocardial injury in hyperlipidemic mice through ROS-pyroptosis signaling pathway.
Ecotoxicology and environmental safety
Jia R,Wei M,Lei J,Meng X,Du R,Yang M,Lu X,Jiang Y,Cao R,Wang L,Song L
Sat Apr 01 00:00:00 EDT 2023
Castor1 overexpression regulates microglia M1/M2 polarization via inhibiting mTOR pathway.
Metabolic brain disease
Hu H,Lu X,Huang L,He Y,Liu X,Wang Y,Duan C
Wed Feb 01 00:00:00 EST 2023
Taurine alleviates ochratoxin A-induced pyroptosis in PK-15 cells by inhibiting oxidative stress.
Journal of biochemical and molecular toxicology
Qu J,Liu K,Liu S,Yue D,Zhang P,Mao X,He W,Huang K,Chen X
Wed Feb 01 00:00:00 EST 2023
Amelioration of nerve demyelination by hydrogen-producing silicon-based agent in neuropathic pain rats.
International immunopharmacology
Mu G,Li Q,Lu B,Yu X
Sat Apr 01 00:00:00 EDT 2023
Selenium Deficiency Promotes the Expression of LncRNA-MORC3, Activating NLRP3-Caspase-1/IL-1β Signaling to Induce Inflammatory Damage and Disrupt Tight Junctions in Piglets.
Biological trace element research
Xue Y,Wang H,Tian B,Wang S,Gao XJ
Mon May 01 00:00:00 EDT 2023
M2 Macrophage Membrane-Mediated Biomimetic-Nanoparticle Carrying COX-siRNA Targeted Delivery for Prevention of Tendon Adhesions by Inhibiting Inflammation.
Small (Weinheim an der Bergstrasse, Germany)
Sun J,Ju F,Jin J,Wang HL,Li ZJ,Sun YC,Chen QZ,Yang QQ,Tan J,Zhou YL
Tue Aug 01 00:00:00 EDT 2023
M2 Macrophage Membrane-Mediated Biomimetic-Nanoparticle Carrying COX-siRNA Targeted Delivery for Prevention of Tendon Adhesions by Inhibiting Inflammation.
Small (Weinheim an der Bergstrasse, Germany)
Sun J,Ju F,Jin J,Wang HL,Li ZJ,Sun YC,Chen QZ,Yang QQ,Tan J,Zhou YL
Tue Aug 01 00:00:00 EDT 2023
Inhibiting NLRP3 Inflammasome Activation by CY-09 Helps to Restore Cerebral Glucose Metabolism in 3×Tg-AD Mice.
Antioxidants (Basel, Switzerland)
Han S,He Z,Hu X,Li X,Zheng K,Huang Y,Xiao P,Xie Q,Ni J,Liu Q
Wed Mar 15 00:00:00 EDT 2023
Stem cell-derived hepatocyte therapy using versatile biomimetic nanozyme incorporated nanofiber-reinforced decellularized extracellular matrix hydrogels for the treatment of acute liver failure.
Bioactive materials
Jin Y,Zhang J,Xu Y,Yi K,Li F,Zhou H,Wang H,Chan HF,Lao YH,Lv S,Tao Y,Li M
Sun Oct 01 00:00:00 EDT 2023
The Nrf2/HMGB1/NF-κB axis modulates chondrocyte apoptosis and extracellular matrix degradation in osteoarthritis.
Acta biochimica et biophysica Sinica
Li W,Tao C,Mao M,Zhu K
Fri May 26 00:00:00 EDT 2023
Transcription factor Dmrt1 triggers the SPRY1-NF-κB pathway to maintain testicular immune homeostasis and male fertility.
Zoological research
Zhang MF,Wan SC,Chen WB,Yang DH,Liu WQ,Li BL,Aierken A,Du XM,Li YX,Wu WP,Yang XC,Wei YD,Li N,Peng S,Li XL,Li GP,Hua JL
Thu May 18 00:00:00 EDT 2023
Scutellaria baicalensis Pith-decayed Root Inhibits Macrophage-related Inflammation Through the NF-κB/NLRP3 Pathway to Alleviate LPS-induced Acute Lung Injury.
Planta medica
Zhang F,Ke C,Zhou Z,Xu K,Wang Y,Liu Y,Tu J
Sat Apr 01 00:00:00 EDT 2023
Scutellaria baicalensis Pith-decayed Root Inhibits Macrophage-related Inflammation Through the NF-κB/NLRP3 Pathway to Alleviate LPS-induced Acute Lung Injury.
Planta medica
Zhang F,Ke C,Zhou Z,Xu K,Wang Y,Liu Y,Tu J
Sat Apr 01 00:00:00 EDT 2023
Scutellaria baicalensis Pith-decayed Root Inhibits Macrophage-related Inflammation Through the NF-κB/NLRP3 Pathway to Alleviate LPS-induced Acute Lung Injury.
Planta medica
Zhang F,Ke C,Zhou Z,Xu K,Wang Y,Liu Y,Tu J
Sat Apr 01 00:00:00 EDT 2023
Scutellaria baicalensis Pith-decayed Root Inhibits Macrophage-related Inflammation Through the NF-κB/NLRP3 Pathway to Alleviate LPS-induced Acute Lung Injury.
Planta medica
Zhang F,Ke C,Zhou Z,Xu K,Wang Y,Liu Y,Tu J
Sat Apr 01 00:00:00 EDT 2023
Synergistic effects of lipopolysaccharide and rotenone on dopamine neuronal damage in rats.
CNS neuroscience & therapeutics
He JY,Li DD,Wen Q,Qin TY,Long H,Zhang SB,Zhang F
Tue Aug 01 00:00:00 EDT 2023
(+)-Borneol exerts neuroprotective effects via suppressing the NF-κB pathway in the pilocarpine-induced epileptogenesis rat model.
Brain research
Gao F,Chen R,Li S,Li A,Bai B,Mi R,Xue G
Sat Jul 01 00:00:00 EDT 2023
Hesperidin mitigates oxidative stress-induced ferroptosis in nucleus pulposus cells via Nrf2/NF-κB axis to protect intervertebral disc from degeneration.
Cell cycle (Georgetown, Tex.)
Zhu J,Sun R,Yan C,Sun K,Gao L,Zheng B,Shi J
Mon May 01 00:00:00 EDT 2023
Single-cell sequencing reveals the immune microenvironment landscape related to anti-PD-1 resistance in metastatic colorectal cancer with high microsatellite instability.
BMC medicine
Wu T,Zhang X,Liu X,Cai X,Shen T,Pan D,Liang R,Ding R,Hu R,Dong J,Li F,Li J,Xie L,Wang C,Geng S,Yang Z,Xing L,Li Y
Thu Apr 27 00:00:00 EDT 2023
Single-cell sequencing reveals the immune microenvironment landscape related to anti-PD-1 resistance in metastatic colorectal cancer with high microsatellite instability.
BMC medicine
Wu T,Zhang X,Liu X,Cai X,Shen T,Pan D,Liang R,Ding R,Hu R,Dong J,Li F,Li J,Xie L,Wang C,Geng S,Yang Z,Xing L,Li Y
Thu Apr 27 00:00:00 EDT 2023
Single-cell sequencing reveals the immune microenvironment landscape related to anti-PD-1 resistance in metastatic colorectal cancer with high microsatellite instability.
BMC medicine
Wu T,Zhang X,Liu X,Cai X,Shen T,Pan D,Liang R,Ding R,Hu R,Dong J,Li F,Li J,Xie L,Wang C,Geng S,Yang Z,Xing L,Li Y
Thu Apr 27 00:00:00 EDT 2023
Single-cell sequencing reveals the immune microenvironment landscape related to anti-PD-1 resistance in metastatic colorectal cancer with high microsatellite instability.
BMC medicine
Wu T,Zhang X,Liu X,Cai X,Shen T,Pan D,Liang R,Ding R,Hu R,Dong J,Li F,Li J,Xie L,Wang C,Geng S,Yang Z,Xing L,Li Y
Thu Apr 27 00:00:00 EDT 2023
Exosomal RBP4 potentiated hepatic lipid accumulation and inflammation in high-fat-diet-fed mice by promoting M1 polarization of Kupffer cells.
Free radical biology & medicine
Yao JM,Ying HZ,Zhang HH,Qiu FS,Wu JQ,Yu CH
Wed Feb 01 00:00:00 EST 2023
Blockage of TRPV4 Downregulates the Nuclear Factor-Kappa B Signaling Pathway to Inhibit Inflammatory Responses and Neuronal Death in Mice with Pilocarpine-Induced Status Epilepticus.
Cellular and molecular neurobiology
An D,Qi X,Li K,Xu W,Wang Y,Chen X,Sha S,Wu C,Du Y,Chen L
Sat Apr 01 00:00:00 EDT 2023
HCH6-1, an antagonist of formyl peptide receptor-1, exerts anti-neuroinflammatory and neuroprotective effects in cellular and animal models of Parkinson's disease.
Biochemical pharmacology
Wang HL,Cheng YC,Yeh TH,Liu HF,Weng YH,Chen RS,Chen YC,Lu JC,Hwang TL,Wei KC,Liu YC,Wang YT,Hsu CC,Chiu TJ,Chiu CC
Thu Jun 01 00:00:00 EDT 2023
Adrenomedullin Improves Hypertension and Vascular Remodeling partly through the Receptor-Mediated AMPK Pathway in Rats with Obesity-Related Hypertension.
International journal of molecular sciences
Wang HY,Wang FZ,Chang R,Wang Q,Liu SY,Cheng ZX,Gao Q,Zhou H,Zhou YB
Wed Feb 15 00:00:00 EST 2023
Novel long non-coding RNAs associated with inflammation and macrophage activation in human.
Scientific reports
Chini A,Guha P,Malladi VS,Guo Z,Mandal SS
Fri Mar 10 00:00:00 EST 2023
The combined effect of deoxynivalenol and Fumonisin B1 on small intestinal inflammation mediated by pyroptosis in vivo and in vitro.
Toxicology letters
Mao X,Zhang P,Du H,Ge L,Liu S,Huang K,Chen X
Sun Jan 01 00:00:00 EST 2023
Stigmasterol Protects Against Steatohepatitis Induced by High-Fat and High-Cholesterol Diet in Mice by Enhancing the Alternative Bile Acid Synthesis Pathway.
The Journal of nutrition
Xin Y,Li X,Zhu X,Lin X,Luo M,Xiao Y,Ruan Y,Guo H
Sat Jul 01 00:00:00 EDT 2023
microRNA-149-5p mediates the PM2.5-induced inflammatory response by targeting TAB2 via MAPK and NF-κB signaling pathways in vivo and in vitro.
Cell biology and toxicology
Li Q,Li S,Xu C,Zhao J,Hou L,Jiang F,Zhu Z,Wang Y,Tian L
Thu Jun 01 00:00:00 EDT 2023
MDM2 upregulation induces mitophagy deficiency via Mic60 ubiquitination in fetal microglial inflammation and consequently neuronal DNA damage caused by exposure to ZnO-NPs during pregnancy.
Journal of hazardous materials
Zhang Y,Zhang Y,Lei Y,Wu J,Kang Y,Zheng S,Shao L
Tue Sep 05 00:00:00 EDT 2023
Fusobacterium nucleatum promotes esophageal squamous cell carcinoma progression and chemoresistance by enhancing the secretion of chemotherapy-induced senescence-associated secretory phenotype via activation of DNA damage response pathway.
Gut microbes
Zhang JW,Zhang D,Yin HS,Zhang H,Hong KQ,Yuan JP,Yu BP
Thu Apr 06 00:00:00 EDT 2023
Elevated Pro-inflammatory Cytokine Levels in Acute Reflux Esophagitis Are Reduced by 1,25 Dihydroxy Vitamin D3.
In vivo (Athens, Greece)
Wei J,Zhang J,Jiang Y,Lian T,Zhang P,Hoffman RM,Zhu G,Zhuang Z
Wed Jan 04 00:00:00 EST 2023
Hybrids of carbonic anhydrase and cyclooxygenase inhibitors attenuate cardiac hypoxic inflammatory injuries.
European journal of pharmacology
Zhou W,Wang C,Zhang B,Gou S
Wed Jul 05 00:00:00 EDT 2023
The expression of cyclic GMP-AMP synthase in human apical periodontitis: A laboratory investigation.
International endodontic journal
Yang F,Liu L,Wang L,Ji X,Zeng Y,Du J,Zhang L,Huang D
Thu Jun 01 00:00:00 EDT 2023
Trimethylamine-N-Oxide Promotes High-Glucose-Induced Dysfunction and NLRP3 Inflammasome Activation in Retinal Microvascular Endothelial Cells.
Journal of ophthalmology
Xue L,Huang L,Tian Y,Cao X,Song Y
Sat Mar 11 00:00:00 EST 2023
Role of NF-κB in lead exposure-induced activation of astrocytes based on bioinformatics analysis of hippocampal proteomics.
Chemico-biological interactions
Fan S,Weixuan W,Han H,Liansheng Z,Gang L,Jierui W,Yanshu Z
Wed Jan 25 00:00:00 EST 2023
Role of nuclear factor of activated T Cells-1 in Sepsis-induced behavioral deficits in mice.
Brain research
Jiang F,Guo Y,Hu L,Zhang M,Meng J,Si Y,Shi H
Mon May 01 00:00:00 EDT 2023
FNDC5/Irisin Inhibits the Inflammatory Response and Mediates the Aerobic Exercise-Induced Improvement of Liver Injury after Myocardial Infarction.
International journal of molecular sciences
Wang T,Yu M,Li H,Qin S,Ren W,Ma Y,Bo W,Xi Y,Cai M,Tian Z
Sun Feb 19 00:00:00 EST 2023
Chronic Microcystin-LR-Induced α-Synuclein Promotes Neuroinflammation Through Activation of the NLRP3 Inflammasome in Microglia.
Molecular neurobiology
Yan M,Jin H,Pan C,Han X
Wed Feb 01 00:00:00 EST 2023
Chronic Microcystin-LR-Induced α-Synuclein Promotes Neuroinflammation Through Activation of the NLRP3 Inflammasome in Microglia.
Molecular neurobiology
Yan M,Jin H,Pan C,Han X
Wed Feb 01 00:00:00 EST 2023
Atractylodin targets GLA to regulate D-mannose metabolism to inhibit osteogenic differentiation of human valve interstitial cells and ameliorate aortic valve calcification.
Phytotherapy research : PTR
Qu L,Wang C,Xu H,Li L,Liu Y,Wan Q,Xu K
Wed Feb 01 00:00:00 EST 2023
Astragaloside IV attenuates high glucose-induced NF-κB-mediated inflammation through activation of PI3K/AKT-ERK-dependent Nrf2/ARE signaling pathway in glomerular mesangial cells.
Phytotherapy research : PTR
Su X,Guo H,Zhou Y,Cao A,Shen Q,Zhu B,Yao X,Wang Y,Wang H,Wang L
Fri Sep 01 00:00:00 EDT 2023
Arthritic Microenvironment Actuated Nanomotors for Active Rheumatoid Arthritis Therapy.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Xu C,Jiang Y,Wang H,Zhang Y,Ye Y,Qin H,Gao J,Dan Q,Du L,Liu L,Peng F,Li Y,Tu Y
Wed Feb 01 00:00:00 EST 2023
LOXL1-AS1 Aggravates Myocardial Ischemia/Reperfusion Injury Through the miR-761/PTEN Axis.
Korean circulation journal
He W,Duan L,Zhang L
Thu Jun 01 00:00:00 EDT 2023
CB2R activation ameliorates late adolescent chronic alcohol exposure-induced anxiety-like behaviors during withdrawal by preventing morphological changes and suppressing NLRP3 inflammasome activation in prefrontal cortex microglia in mice.
Brain, behavior, and immunity
Li J,Wang H,Liu D,Li X,He L,Pan J,Shen Q,Peng Y
Mon May 01 00:00:00 EDT 2023
A short peptide exerts neuroprotective effects on cerebral ischemia-reperfusion injury by reducing inflammation via the miR-6328/IKKβ/NF-κB axis.
Journal of neuroinflammation
Li Y,Jin T,Liu N,Wang J,Qin Z,Yin S,Zhang Y,Fu Z,Wu Y,Wang Y,Liu Y,Yang M,Pang A,Sun J,Wang Y,Yang X
Tue Feb 28 00:00:00 EST 2023
Combined exposure to lead and high-fat diet induced neuronal deficits in rats: Anti-neuroinflammatory role of SIRT1.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Liu M,Liu R,Yang M,Ba Y,Deng Q,Zhang Y,Han L,Gao L,Huang H
Sat Jul 01 00:00:00 EDT 2023
PPARα Inhibits Astrocyte Inflammation Activation by Restoring Autophagic Flux after Transient Brain Ischemia.
Biomedicines
Luo D,Ye W,Chen L,Yuan X,Zhang Y,Chen C,Jin X,Zhou Y
Tue Mar 21 00:00:00 EDT 2023
Expression pattern analysis of m6A regulators reveals IGF2BP3 as a key modulator in osteoarthritis synovial macrophages.
Journal of translational medicine
Lu Y,Zhang H,Pan H,Zhang Z,Zeng H,Xie H,Yin J,Tang W,Lin R,Zeng C,Cai D
Mon May 22 00:00:00 EDT 2023
Expression pattern analysis of m6A regulators reveals IGF2BP3 as a key modulator in osteoarthritis synovial macrophages.
Journal of translational medicine
Lu Y,Zhang H,Pan H,Zhang Z,Zeng H,Xie H,Yin J,Tang W,Lin R,Zeng C,Cai D
Mon May 22 00:00:00 EDT 2023
Progesterone Enhances the Invasion of Trophoblast Cells by Activating PI3K/AKT Signaling Pathway to Prevent Preeclampsia.
Cell transplantation
Liu H,Yu L,Ding Y,Peng M,Deng Y
Wed Jan 04 00:00:00 EST 2023
Baicalin Attenuates Continuous Activation of β-Catenin Induced by Lipopolysaccharide (LPS) and Depression Complicated by Infertility in Male Rats.
Evidence-based complementary and alternative medicine : eCAM
Fan R,Dai F,Zhang C,Zhou L,Qiu X,Li Y
Sat Jul 16 00:00:00 EDT 2022
Sodium butyrate alleviates pre-eclampsia in pregnant rats by improving the gut microbiota and short-chain fatty acid metabolites production.
Journal of applied microbiology
Yong W,Zhao Y,Jiang X,Li P
Tue Feb 01 00:00:00 EST 2022
Betaine supplementation alleviates dextran sulfate sodium-induced colitis via regulating the inflammatory response, enhancing the intestinal barrier, and altering gut microbiota.
Food & function
Zhao N,Yang Y,Chen C,Jing T,Hu Y,Xu H,Wang S,He Y,Liu E,Cui J
Tue Dec 13 00:00:00 EST 2022
LncRNA FENDRR with m6A RNA methylation regulates hypoxia-induced pulmonary artery endothelial cell pyroptosis by mediating DRP1 DNA methylation.
Molecular medicine (Cambridge, Mass.)
Wang X,Li Q,He S,Bai J,Ma C,Zhang L,Guan X,Yuan H,Li Y,Zhu X,Mei J,Gao F,Zhu D
Tue Oct 25 00:00:00 EDT 2022
Resolution of systemic complications in Schistosoma mansoni-infected mice by concomitant treatment with praziquantel and Schisandrin B.
International journal for parasitology
Lam HYP,Cheng PC,Peng SY
Fri Apr 01 00:00:00 EDT 2022
Magnolol limits NFκB-dependent inflammation by targeting PPARγ relieving retinal ischemia/reperfusion injury.
International immunopharmacology
Wang N,Yang Y,Liu Y,Huang L,Gu M,Wu Y,Xu L,Sun H,Guo W
Tue Nov 01 00:00:00 EDT 2022
Panax notoginseng Saponins Attenuate Cerebral Ischemia-Reperfusion Injury via Mitophagy-Induced Inhibition of NLRP3 Inflammasome in Rats.
Frontiers in bioscience (Landmark edition)
Xiao Q,Kang Z,Liu C,Tang B
Thu Nov 03 00:00:00 EDT 2022
linc00174 deteriorates the pathogenesis of diabetic retinopathy via miR-26a-5p/PTEN/Akt signalling cascade-mediated pyroptosis.
Biochemical and biophysical research communications
Wang JJ,Chen ZL,Wang DD,Wu KF,Huang WB,Zhang LQ
Sat Nov 19 00:00:00 EST 2022
Adrenomedullin Improves Cardiac Remodeling and Function in Obese Rats with Hypertension.
Pharmaceuticals (Basel, Switzerland)
Qian P,Wang Q,Wang FZ,Dai HB,Wang HY,Gao Q,Zhou H,Zhou YB
Mon Jun 06 00:00:00 EDT 2022
SGLT2 inhibitor, canagliflozin, ameliorates cardiac inflammation in experimental autoimmune myocarditis.
International immunopharmacology
Long Q,Li L,Yang H,Lu Y,Yang H,Zhu Y,Tang Y,Liu C,Yuan J
Thu Sep 01 00:00:00 EDT 2022
Treadmill exercise training alleviates diabetes-induced depressive-like behavior and cognitive impairment by improving hippocampal CA1 neurons injury in db/db mice.
Brain research bulletin
Zhou Z,Wang M,Huang C,Li Y,Gao L,Zhu Y,Ying C,Zhou X
Tue Nov 01 00:00:00 EDT 2022
S100A8-Mediated NLRP3 Inflammasome-Dependent Pyroptosis in Macrophages Facilitates Liver Fibrosis Progression.
Cells
Liu Y,Kong X,You Y,Xiang L,Zhang Y,Wu R,Zhou L,Duan L
Sat Nov 12 00:00:00 EST 2022
S100A8-Mediated NLRP3 Inflammasome-Dependent Pyroptosis in Macrophages Facilitates Liver Fibrosis Progression.
Cells
Liu Y,Kong X,You Y,Xiang L,Zhang Y,Wu R,Zhou L,Duan L
Sat Nov 12 00:00:00 EST 2022
S100A8-Mediated NLRP3 Inflammasome-Dependent Pyroptosis in Macrophages Facilitates Liver Fibrosis Progression.
Cells
Liu Y,Kong X,You Y,Xiang L,Zhang Y,Wu R,Zhou L,Duan L
Sat Nov 12 00:00:00 EST 2022
S100A8-Mediated NLRP3 Inflammasome-Dependent Pyroptosis in Macrophages Facilitates Liver Fibrosis Progression.
Cells
Liu Y,Kong X,You Y,Xiang L,Zhang Y,Wu R,Zhou L,Duan L
Sat Nov 12 00:00:00 EST 2022
Platonin protects against cerebral ischemia/reperfusion injury in rats by inhibiting NLRP3 inflammasomes via BNIP3/LC3 signaling mediated autophagy.
Brain research bulletin
Luo J,Tan J,Jiang N,Yang C,Chen J,Zhao J,Li L,Zhao Y
Tue Mar 01 00:00:00 EST 2022
Gastrodin ameliorates the lipopolysaccharide-induced neuroinflammation in mice by downregulating miR-107-3p.
Frontiers in pharmacology
Song JJ,Li H,Wang N,Zhou XY,Liu Y,Zhang Z,Feng Q,Chen YL,Liu D,Liang J,Ma XY,Wen XR,Fu YY
Tue Dec 27 00:00:00 EST 2022
Isoliquiritigenin attenuates neuroinflammation in mice model of Parkinson's disease by promoting Nrf2/NQO-1 pathway.
Translational neuroscience
Huang L,Han Y,Zhou Q,Sun Z,Yan J
Sat Jan 01 00:00:00 EST 2022
Urolithin A promotes mitophagy and suppresses NLRP3 inflammasome activation in lipopolysaccharide-induced BV2 microglial cells and MPTP-induced Parkinson's disease model.
Neuropharmacology
Qiu J,Chen Y,Zhuo J,Zhang L,Liu J,Wang B,Sun D,Yu S,Lou H
Fri Apr 01 00:00:00 EDT 2022
Multifunctional Silk Fibroin Methacryloyl Microneedle for Diabetic Wound Healing.
Small (Weinheim an der Bergstrasse, Germany)
Guan G,Zhang Q,Jiang Z,Liu J,Wan J,Jin P,Lv Q
Thu Dec 01 00:00:00 EST 2022
Exosome-Shuttled miR-672-5p from Anti-Inflammatory Microglia Repair Traumatic Spinal Cord Injury by Inhibiting AIM2/ASC/Caspase-1 Signaling Pathway Mediated Neuronal Pyroptosis.
Journal of neurotrauma
Zhou Z,Li C,Bao T,Zhao X,Xiong W,Luo C,Yin G,Fan J
Mon Aug 01 00:00:00 EDT 2022
Exosome-Shuttled miR-672-5p from Anti-Inflammatory Microglia Repair Traumatic Spinal Cord Injury by Inhibiting AIM2/ASC/Caspase-1 Signaling Pathway Mediated Neuronal Pyroptosis.
Journal of neurotrauma
Zhou Z,Li C,Bao T,Zhao X,Xiong W,Luo C,Yin G,Fan J
Mon Aug 01 00:00:00 EDT 2022
Pyroptosis relates to tumor microenvironment remodeling and prognosis: A pan-cancer perspective.
Frontiers in immunology
Khan M,Ai M,Du K,Song J,Wang B,Lin J,Ren A,Chen C,Huang Z,Qiu W,Zhang J,Tian Y,Yuan Y
Tue Jan 10 00:00:00 EST 2023
Neuroprotection of cannabidiol in epileptic rats: Gut microbiome and metabolome sequencing.
Frontiers in nutrition
Gong X,Liu L,Li X,Xiong J,Xu J,Mao D,Liu L
Tue Dec 06 00:00:00 EST 2022
Effect of benzo(a)pyrene on oxidative stress and inflammatory mediators in astrocytes and HIV-infected macrophages.
PloS one
Kumar A,Sinha N,Kodidela S,Zhou L,Singh UP,Kumar S
Tue Oct 18 00:00:00 EDT 2022
Hydrogen Sulfide Ameliorated High Choline-Induced Cardiac Dysfunction by Inhibiting cGAS-STING-NLRP3 Inflammasome Pathway.
Oxidative medicine and cellular longevity
Bai L,Dai J,Xia Y,He K,Xue H,Guo Q,Tian D,Xiao L,Zhang X,Teng X,Wu Y,Jin S
Tue Aug 02 00:00:00 EDT 2022
Pulsed electromagnetic field alleviates synovitis and inhibits the NLRP3/Caspase-1/GSDMD signaling pathway in osteoarthritis rats.
Electromagnetic biology and medicine
Liu J,Huang X,Zhou J,Li L,Xiao H,Qu M,Sun Z
Sun Jan 02 00:00:00 EST 2022
Hippocampus-Based Mitochondrial Respiratory Function Decline Is Responsible for Perioperative Neurocognitive Disorders.
Frontiers in aging neuroscience
He K,Zhang J,Zhang W,Wang S,Li D,Ma X,Wu X,Chai X,Liu Q
Tue Mar 01 00:00:00 EST 2022
Protection of CAPE-pNO2 Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro.
Inflammation
Wan Q,Zhang L,Zhou Q,Han Y,Li Z,Li B
Wed Jun 01 00:00:00 EDT 2022
Neutrophil Extracellular Traps Regulate HMGB1 Translocation and Kupffer Cell M1 Polarization During Acute Liver Transplantation Rejection.
Frontiers in immunology
Liu Y,Pu X,Qin X,Gong J,Huang Z,Luo Y,Mou T,Zhou B,Shen A,Wu Z
Tue May 24 00:00:00 EDT 2022
Selenomethionine alleviated Ochratoxin A induced pyroptosis and renal fibrotic factors expressions in MDCK cells.
Journal of biochemical and molecular toxicology
Mao X,Li H,Ge L,Liu S,Hou L,Yue D,Du H,Pan C,Gan F,Liu Y,Huang K,Chen X
Sat Jan 01 00:00:00 EST 2022
Hyaluronic acids mediate the infiltration, migration, and M2 polarization of macrophages: evaluating metabolic molecular phenotypes in gliomas.
Molecular oncology
Zhang H,Zhang N,Dai Z,Wang Z,Zhang X,Liang X,Zhang L,Feng S,Wu W,Ye W,Zhang J,Luo P,Liu Z,Cheng Q,Liu Z
Thu Dec 01 00:00:00 EST 2022
Identification of key proteins of cytopathic biotype bovine viral diarrhoea virus involved in activating NF-κB pathway in BVDV-induced inflammatory response.
Virulence
Fan W,Wang Y,Jiang S,Li Y,Yao X,Wang M,Zhao J,Sun X,Jiang X,Zhong L,Han Y,Song H,Xu Y
Thu Dec 01 00:00:00 EST 2022
Atractylodes lancea Rhizoma Attenuates DSS-Induced Colitis by Regulating Intestinal Flora and Metabolites.
The American journal of Chinese medicine
Qu L,Liu C,Ke C,Zhan X,Li L,Xu H,Xu K,Liu Y
Mon Mar 21 00:00:00 EDT 2022
Construction and comprehensive analysis of a lncRNA-mRNA interactive network to reveal a potential lncRNA for hepatic encephalopathy development.
Human cell
Zhang C,Ni W,Zhu Y,Lin J,Li H,Zhao Z,Wang K,Huo H,Luo M
Fri Jul 01 00:00:00 EDT 2022
Modification of taxifolin particles with an enteric coating material promotes repair of acute liver injury in mice through modulation of inflammation and autophagy signaling pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Ding Q,Chen K,Liu X,Ding C,Zhao Y,Sun S,Zhang Y,Zhang J,Liu S,Liu W
Mon Aug 01 00:00:00 EDT 2022
Pyroptosis participates in PM2.5-induced air-blood barrier dysfunction.
Environmental science and pollution research international
Jia R,Wei M,Zhang X,Du R,Sun W,Wang L,Song L
Mon Aug 01 00:00:00 EDT 2022
Transfer of Tumor-Bearing Mice Intestinal Flora Can Ameliorate Cognition in Alzheimer's Disease Mice.
Journal of Alzheimer's disease : JAD
Hang Z,Cai S,Lei T,Zhang X,Xiao Z,Wang D,Li Y,Bi W,Yang Y,Deng S,Wang L,Li Q,Du H
Wed Apr 13 00:00:00 EDT 2022
A Novel Mast Cell Stabilizer JM25-1 Rehabilitates Impaired Gut Barrier by Targeting the Corticotropin-Releasing Hormone Receptors.
Pharmaceuticals (Basel, Switzerland)
Sun Y,Li H,Liu L,Bai X,Wu L,Shan J,Sun X,Wang Q,Guo Y
Thu Dec 29 00:00:00 EST 2022
Bisdemethoxycurcumin Alleviates Dextran Sodium Sulfate-Induced Colitis via Inhibiting NLRP3 Inflammasome Activation and Modulating the Gut Microbiota in Mice.
Antioxidants (Basel, Switzerland)
Zhang J,Li Q,Zhang X,Chen Y,Lu Y,Wang X,Zhang L,Wang T
Fri Oct 07 00:00:00 EDT 2022
Metabolic Reprogramming of Microglia Enhances Proinflammatory Cytokine Release through EphA2/p38 MAPK Pathway in Alzheimer's Disease.
Journal of Alzheimer's disease : JAD
Ma X,Zhang Y,Gou D,Ma J,Du J,Wang C,Li S,Cui H
Tue Jul 26 00:00:00 EDT 2022
Fructose Induces Insulin Resistance of Gestational Diabetes Mellitus in Mice via the NLRP3 Inflammasome Pathway.
Frontiers in nutrition
Liu Y,Wei Y,Wu L,Lin X,Sun R,Chen H,Shen S,Deng G
Tue May 03 00:00:00 EDT 2022
Rice protein suppresses 4-hydroxy-2-nonenal-induced inflammation owing to methionine availability.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme
Wang Z,Liang M,Li H,Liu B,Yang L
Mon Aug 01 00:00:00 EDT 2022
Atractylenolide-1 targets SPHK1 and B4GALT2 to regulate intestinal metabolism and flora composition to improve inflammation in mice with colitis.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Qu L,Shi K,Xu J,Liu C,Ke C,Zhan X,Xu K,Liu Y
Fri Apr 01 00:00:00 EDT 2022
Use of wogonin as a cooperative drug with praziquantel to better combat schistosomiasis.
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
Pekkle Lam HY,Hung MY,Cheng PC,Peng SY
Mon Aug 01 00:00:00 EDT 2022
Ganluyin ameliorates DSS-induced ulcerative colitis by inhibiting the enteric-origin LPS/TLR4/NF-κB pathway.
Journal of ethnopharmacology
Xiong T,Zheng X,Zhang K,Wu H,Dong Y,Zhou F,Cheng B,Li L,Xu W,Su J,Huang J,Jiang Z,Li B,Zhang B,Lv G,Chen S
Tue May 10 00:00:00 EDT 2022
Procyanidins and its metabolites by gut microbiome improves insulin resistance in gestational diabetes mellitus mice model via regulating NF-κB and NLRP3 inflammasome pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Liu Y,Sun R,Lin X,Wu L,Chen H,Shen S,Li Y,Wei Y,Deng G
Fri Jul 01 00:00:00 EDT 2022
Sauchinone alleviates dextran sulfate sodium-induced ulcerative colitis via NAD(P)H dehydrogenase [quinone] 1/NF-kB pathway and gut microbiota.
Frontiers in microbiology
Wu K,Liu X,Meng X,Cao L,Li H,Bi Y,Wang M,Wang M,Jiang Y
Thu Feb 02 00:00:00 EST 2023
Sodium Tanshinone IIA Sulfonate Inhibits Vascular Endothelial Cell Pyroptosis via the AMPK Signaling Pathway in Atherosclerosis.
Journal of inflammation research
Zhu J,Chen H,Guo J,Zha C,Lu D
Tue Nov 22 00:00:00 EST 2022
Isoliquiritigenin-mediated miR-23a-3p inhibition activates PGC-1α to alleviate alcoholic liver injury.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wang L,Kong L,Xu S,Wang X,Huang K,Wang S,Wu J,Wang C,Sun H,Liu K,Meng Q
Tue Feb 01 00:00:00 EST 2022
Neddylation Inhibition Causes Impaired Mouse Embryo Quality and Blastocyst Hatching Failure Through Elevated Oxidative Stress and Reduced IL-1β.
Frontiers in immunology
Yang G,Chen J,He Y,Luo H,Yuan H,Chen L,Huang L,Mao F,Hu S,Qian Y,Miao C,Feng R
Fri Jul 22 00:00:00 EDT 2022
Lactobacillus casei SYF-08 Protects Against Pb-Induced Injury in Young Mice by Regulating Bile Acid Metabolism and Increasing Pb Excretion.
Frontiers in nutrition
Chen Z,Tang Z,Kong J,Chen L,Liu J,Li Y,Huang W,Li W,Wu J,Zhao W,Meng X,Fan H
Tue Jul 19 00:00:00 EDT 2022
Oridonin Delays Aging Through the AKT Signaling Pathway.
Frontiers in pharmacology
An Y,Zhu J,Wang X,Sun X,Luo C,Zhang Y,Ye Y,Li X,Abulizi A,Huang Z,Zhang H,Yang B,Xie Z
Sat Jul 16 00:00:00 EDT 2022
Dual Effects: Intrastriatal Injection of α-syn N103/tau N368 Preformed Fibrils Promotes Endogenous α-synuclein Aggregates in the Proximal Colon.
Journal of Parkinson's disease
Wang J,Yang X,Zeng W,Zhang X,Yang X,Xu Y,Liu K,Zhang Z,Xu Y,Cao X
Tue Oct 18 00:00:00 EDT 2022
Trehalose inhibits ferroptosis via NRF2/HO-1 pathway and promotes functional recovery in mice with spinal cord injury.
Aging
Gong F,Ge T,Liu J,Xiao J,Wu X,Wang H,Zhu Y,Xia D,Hu B
Sun Apr 10 00:00:00 EDT 2022
JQ1 attenuates neuroinflammation by inhibiting the inflammasome-dependent canonical pyroptosis pathway in SAE.
Brain research bulletin
Zhong X,Chen Z,Wang Y,Mao M,Deng Y,Shi M,Xu Y,Chen L,Cao W
Sat Oct 15 00:00:00 EDT 2022
Luteolin Induced Hippocampal Neuronal Pyroptosis Inhibition by Regulation of miR-124-3p/TNF-α/TRAF6 Axis in Mice Affected by Breast-Cancer-Related Depression.
Evidence-based complementary and alternative medicine : eCAM
Zhu Q,Meng P,Han Y,Yang H,Yang Q,Liu Z,Wang Y,Long M
Sat Jul 16 00:00:00 EDT 2022
Oryzanol Attenuates High Fat and Cholesterol Diet-Induced Hyperlipidemia by Regulating the Gut Microbiome and Amino Acid Metabolism.
Journal of agricultural and food chemistry
Yan S,Chen J,Zhu L,Guo T,Qin D,Hu Z,Han S,Zhou Y,Akan OD,Wang J,Luo F,Lin Q
Wed Jun 01 00:00:00 EDT 2022
Grossamide attenuates inflammation by balancing macrophage polarization through metabolic reprogramming of macrophages in mice.
International immunopharmacology
Zhao W,Xu D,Hong W,Zhang L,Wu Q,Gao M,Wang J
Tue Nov 01 00:00:00 EDT 2022
Role of salivary glycopatterns for oral microbiota associated with gastric cancer.
International journal of biological macromolecules
Shu J,Yu H,Ren X,Wang Y,Zhang K,Tang Z,Dang L,Chen W,Li B,Xie H,Li Z
Wed Jun 01 00:00:00 EDT 2022
Cancer-associated fibroblasts educate normal fibroblasts to facilitate cancer cell spreading and T-cell suppression.
Molecular oncology
Itoh G,Takagane K,Fukushi Y,Kuriyama S,Umakoshi M,Goto A,Yanagihara K,Yashiro M,Tanaka M
Sat Jan 01 00:00:00 EST 2022
Polarization and β-Glucan Reprogram Immunomodulatory Metabolism in Human Macrophages and Ex Vivo in Human Lung Cancer Tissues.
Journal of immunology (Baltimore, Md. : 1950)
Fan TW,Daneshmandi S,Cassel TA,Uddin MB,Sledziona J,Thompson PT,Lin P,Higashi RM,Lane AN
Tue Nov 01 00:00:00 EDT 2022
Astragaloside IV Alleviates Renal Tubular Epithelial-Mesenchymal Transition via CX3CL1-RAF/MEK/ERK Signaling Pathway in Diabetic Kidney Disease.
Drug design, development and therapy
Hu Y,Tang W,Liu W,Hu Z,Pan C
Wed Jun 08 00:00:00 EDT 2022
Inhibition of glutamine transporter ASCT2 mitigates bleomycin-induced pulmonary fibrosis in mice.
Acta histochemica
Lian N,Jin H,Zhu W,Zhang C,Qi Y,Jiang M,Mao J,Lu X,Zhao F,Xi B,Qi X,Li Y
Thu Dec 01 00:00:00 EST 2022
Effect of NLRP3 repression on NLRP3 inflammasome activation in human corneal epithelial cells with black carbon exposure.
Cutaneous and ocular toxicology
Xiao K,Shang J,Liu Y,Chen Z,Wang L,Long Q
Wed Jun 01 00:00:00 EDT 2022
OPN Promotes Cell Proliferation and Invasion through NF-κB in Human Esophageal Squamous Cell Carcinoma.
Genetics research
Chen B,Liang S,Guo H,Xu L,Li J,Peng J
Wed Jan 11 00:00:00 EST 2023
Mutant C/EBPα p30 alleviates immunosuppression of CD8+ T cells by inhibiting autophagy-associated secretion of IL-1β in AML.
Cell proliferation
Wang JD,Xu JQ,Zhang XN,Huang ZW,Liu LL,Zhang L,Lei XX,Xue MJ,Weng JY,Long ZJ
Thu Dec 01 00:00:00 EST 2022
Mutant C/EBPα p30 alleviates immunosuppression of CD8+ T cells by inhibiting autophagy-associated secretion of IL-1β in AML.
Cell proliferation
Wang JD,Xu JQ,Zhang XN,Huang ZW,Liu LL,Zhang L,Lei XX,Xue MJ,Weng JY,Long ZJ
Thu Dec 01 00:00:00 EST 2022
AQP2 Promotes Astrocyte Activation by Modulating the TLR4/NFκB-p65 Pathway Following Intracerebral Hemorrhage.
Frontiers in immunology
Deng S,Chen X,Lei Q,Lu W
Fri Apr 08 00:00:00 EDT 2022
Rutin Inhibits Ox-LDL-Mediated Macrophage Inflammation and Foam Cell Formation by Inducing Autophagy and Modulating PI3K/ATK Signaling.
Molecules (Basel, Switzerland)
Li B,Ji Y,Yi C,Wang X,Liu C,Wang C,Lu X,Xu X,Wang X
Wed Jun 29 00:00:00 EDT 2022
Supplementation with dietary omega-3 PUFA mitigates fetal brain inflammation and mitochondrial damage caused by high doses of sodium nitrite in maternal rats.
PloS one
Sun J,Zhang W
Wed May 04 00:00:00 EDT 2022
The interaction of O-GlcNAc-modified NLRX1 and IKK-α modulates IL-1β expression in M1 macrophages.
In vitro cellular & developmental biology. Animal
Chen L,Li Y,Zeng S,Duan S,Huang Z,Liang Y
Sun May 01 00:00:00 EDT 2022
Salidroside Ameliorates Depression by Suppressing NLRP3-Mediated Pyroptosis via P2X7/NF-κB/NLRP3 Signaling Pathway.
Frontiers in pharmacology
Chai Y,Cai Y,Fu Y,Wang Y,Zhang Y,Zhang X,Zhu L,Miao M,Yan T
Sat Jul 16 00:00:00 EDT 2022
Betaine Ameliorates Acute Sever Ulcerative Colitis by Inhibiting Oxidative Stress Induced Inflammatory Pyroptosis.
Molecular nutrition & food research
Chen L,Liu D,Mao M,Liu W,Wang Y,Liang Y,Cao W,Zhong X
Tue Nov 01 00:00:00 EDT 2022
Transcriptional landscape of human neuroblastoma cells in response to SARS-CoV-2.
BMC neuroscience
Yang RC,Huang K,Zhang HP,Li L,Tan C,Chen HC,Jin ML,Wang XR
Wed Jul 06 00:00:00 EDT 2022
Guizhi-Shaoyao-Zhimu decoction attenuates monosodium urate crystal-induced inflammation through inactivation of NF-κB and NLRP3 inflammasome.
Journal of ethnopharmacology
Zhou GQ,Chen G,Yang J,Qin WY,Ping J
Sun Jan 30 00:00:00 EST 2022
Magnetic hyperthermia induces effective and genuine immunogenic tumor cell death with respect to exogenous heating.
Journal of materials chemistry. B
Yan B,Liu C,Wang S,Li H,Jiao J,Lee WSV,Zhang S,Hou Y,Hou Y,Ma X,Fan H,Lv Y,Liu X
Wed Jul 20 00:00:00 EDT 2022
The Assessment on Synergistic Activity of Ebselen and Silver Ion Against Yersinia pseudotuberculosis.
Frontiers in microbiology
Dong C,Chen W,Zou L,Liu B,Deng K,Guo D,Wang P,Chen H,Wang H,Wang J
Sat Aug 13 00:00:00 EDT 2022
Gut-Flora-Dependent Metabolite Trimethylamine-N-Oxide Promotes Atherosclerosis-Associated Inflammation Responses by Indirect ROS Stimulation and Signaling Involving AMPK and SIRT1.
Nutrients
Zhou S,Xue J,Shan J,Hong Y,Zhu W,Nie Z,Zhang Y,Ji N,Luo X,Zhang T,Ma W
Mon Aug 15 00:00:00 EDT 2022
MMP2 and MMP9 contribute to lung ischemia-reperfusion injury via promoting pyroptosis in mice.
BMC pulmonary medicine
Zhou P,Song NC,Zheng ZK,Li YQ,Li JS
Wed Jun 15 00:00:00 EDT 2022
Anti-depressant effects of acupuncture: The insights from NLRP3 mediated pyroptosis and inflammation.
Neuroscience letters
Chen Y,Hao C,Chen W,Cheng W,Li P,Shen J,Tong T,Yan S,Huang S,He T,Huang Z,Meng X
Wed Aug 10 00:00:00 EDT 2022
Caspase-1-mediated extracellular vesicles derived from pyroptotic alveolar macrophages promote inflammation in acute lung injury.
International journal of biological sciences
Qin X,Zhou Y,Jia C,Chao Z,Qin H,Liang J,Liu X,Liu Z,Sun T,Yuan Y,Zhang H
Fri Apr 15 00:00:00 EDT 2022
CoQ10 Improves Myocardial Damage in Doxorubicin-Induced Heart Failure in C57BL/6 Mice.
Frontiers in bioscience (Landmark edition)
Pei Z,Ma L,Li Y,Yang J,Yang Q,Yao W,Li S
Mon Aug 15 00:00:00 EDT 2022
P2X7 Receptor-Induced Bone Cancer Pain by Regulating Microglial Activity via NLRP3/IL-1beta Signaling.
Pain physician
Wu P,Wu X,Zhou G,Wang Y,Liu X,Lv R,Liu Y,Wen Q
Tue Nov 01 00:00:00 EDT 2022
Aerobic exercise training alleviates renal injury in db/db mice through inhibiting Nox4-mediated NLRP3 inflammasome activation.
Experimental gerontology
Zhou Z,Ying C,Zhou X,Shi Y,Xu J,Zhu Y,Wang M,Li Y,Li X,Xiang J
Sat Oct 15 00:00:00 EDT 2022
Aerobic exercise training alleviates renal injury in db/db mice through inhibiting Nox4-mediated NLRP3 inflammasome activation.
Experimental gerontology
Zhou Z,Ying C,Zhou X,Shi Y,Xu J,Zhu Y,Wang M,Li Y,Li X,Xiang J
Sat Oct 15 00:00:00 EDT 2022
Isoandrographolide inhibits NLRP3 inflammasome activation and attenuates silicosis in mice.
International immunopharmacology
Song Z,Wang L,Cao Y,Liu Z,Zhang M,Zhang Z,Jiang S,Fan R,Hao T,Yang R,Wang B,Guan Z,Zhu L,Liu Z,Zhang S,Zhao L,Xu Z,Xu H,Dai G
Fri Apr 01 00:00:00 EDT 2022
Isoandrographolide inhibits NLRP3 inflammasome activation and attenuates silicosis in mice.
International immunopharmacology
Song Z,Wang L,Cao Y,Liu Z,Zhang M,Zhang Z,Jiang S,Fan R,Hao T,Yang R,Wang B,Guan Z,Zhu L,Liu Z,Zhang S,Zhao L,Xu Z,Xu H,Dai G
Fri Apr 01 00:00:00 EDT 2022
Injectable self-healing hydrogel with siRNA delivery property for sustained STING silencing and enhanced therapy of intervertebral disc degeneration.
Bioactive materials
Chen J,Zhu H,Zhu Y,Zhao C,Wang S,Zheng Y,Xie Z,Jin Y,Song H,Yang L,Zhang J,Dai J,Hu Z,Wang H
Tue Mar 01 00:00:00 EST 2022
Enriched Environment-Induced Neuroprotection against Cerebral Ischemia-Reperfusion Injury Might Be Mediated via Enhancing Autophagy Flux and Mitophagy Flux.
Mediators of inflammation
Zhang QQ,Luo L,Liu MX,Wang CJ,Wu Y,Yu KW
Fri Jul 08 00:00:00 EDT 2022
Adrenomedullin ameliorates palmitic acid-induced insulin resistance through PI3K/Akt pathway in adipocytes.
Acta diabetologica
Dai HB,Wang HY,Wang FZ,Qian P,Gao Q,Zhou H,Zhou YB
Sun May 01 00:00:00 EDT 2022
Disturbing NLRP3 acetylation and inflammasome assembly inhibits androgen receptor-promoted inflammatory responses and prostate cancer progression.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhao AN,Yang Z,Wang DD,Shi B,Zhang H,Bai Y,Yan BW,Zhang Y,Wen JK,Wang XL,Qu CB
Tue Nov 01 00:00:00 EDT 2022
Disturbing NLRP3 acetylation and inflammasome assembly inhibits androgen receptor-promoted inflammatory responses and prostate cancer progression.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhao AN,Yang Z,Wang DD,Shi B,Zhang H,Bai Y,Yan BW,Zhang Y,Wen JK,Wang XL,Qu CB
Tue Nov 01 00:00:00 EDT 2022
Treadmill training mitigates bone deterioration via inhibiting NLRP3/Caspase1/IL-1β signaling in aged rats.
BMC musculoskeletal disorders
Wu Q,Zhong P,Ning P,Tan L,Huang X,Peng T,Yin L,Luo F,Qu M,Zhou J
Tue Dec 13 00:00:00 EST 2022
Cigarette smoke exposed airway epithelial cell-derived EVs promote pro-inflammatory macrophage activation in alpha-1 antitrypsin deficiency.
Respiratory research
Khodayari N,Oshins R,Mehrad B,Lascano JE,Qiang X,West JR,Holliday LS,Lee J,Wiesemann G,Eydgahi S,Brantly M
Tue Sep 06 00:00:00 EDT 2022
Targeting Vascular endothelial growth factor A with soluble vascular endothelial growth factor receptor 1 ameliorates nerve injury-induced neuropathic pain.
Molecular pain
Peng Z,Yang F,Huang S,Tang Y,Wan L
Fri Apr 01 00:00:00 EDT 2022
Effects of intraperitoneal injection of lipopolysaccharide-induced peripheral inflammation on dopamine neuron damage in rat midbrain.
CNS neuroscience & therapeutics
Yang QY,Li XW,Yang R,Qin TY,Long H,Zhang SB,Zhang F
Sat Oct 01 00:00:00 EDT 2022
Morin Inhibits Dox-Induced Vascular Inflammation By Regulating PTEN/AKT/NF-κB Pathway.
Inflammation
Yu J,Qi HL,Zhang H,Zhao ZY,Nie ZY
Thu Dec 01 00:00:00 EST 2022
Morin Inhibits Dox-Induced Vascular Inflammation By Regulating PTEN/AKT/NF-κB Pathway.
Inflammation
Yu J,Qi HL,Zhang H,Zhao ZY,Nie ZY
Thu Dec 01 00:00:00 EST 2022
Morin Inhibits Dox-Induced Vascular Inflammation By Regulating PTEN/AKT/NF-κB Pathway.
Inflammation
Yu J,Qi HL,Zhang H,Zhao ZY,Nie ZY
Thu Dec 01 00:00:00 EST 2022
L-Se-methylselenocysteine loaded mucoadhesive thermogel for effective treatment of Vulvar candidiasis.
International journal of pharmaceutics
Yang X,Wang M,Kang X,Mo F,Si P,Ma J,Zhang P,Zheng S,Li J,Wang Y,Li Q,Zhang J
Sat Jun 25 00:00:00 EDT 2022
Curcumin suppress inflammatory response in traumatic brain injury via p38/MAPK signaling pathway.
Phytotherapy research : PTR
Li G,Duan L,Yang F,Yang L,Deng Y,Yu Y,Xu Y,Zhang Y
Tue Mar 01 00:00:00 EST 2022
Interleukin-4 activates the PI3K/AKT signaling to promote apoptosis and inhibit the proliferation of granulosa cells.
Experimental cell research
Han Y,Yao R,Yang Z,Li S,Meng W,Zhang Y,Zhang Y,Luo H
Tue Mar 01 00:00:00 EST 2022
Leonurine inhibits the TXNIP/NLRP3 and NF-κB pathways via Nrf2 activation to alleviate carrageenan-induced pleurisy in mice.
Phytotherapy research : PTR
Yan K,Hu J,Hou T,Ci X,Peng L
Sun May 01 00:00:00 EDT 2022
Calcium phosphate cement with icariin-loaded gelatin microspheres as a local drug delivery system for bone regeneration.
Biomedical engineering online
Liu N,Huang S,Guo F,Zhai S,Wang D,Li F,Liu C
Thu Dec 22 00:00:00 EST 2022
Activation of the NLRP3 inflammasome by RAC1 mediates a new mechanism in diabetic nephropathy.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Ying C,Zhou Z,Dai J,Wang M,Xiang J,Sun D,Zhou X
Tue Feb 01 00:00:00 EST 2022
Activation of the NLRP3 inflammasome by RAC1 mediates a new mechanism in diabetic nephropathy.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Ying C,Zhou Z,Dai J,Wang M,Xiang J,Sun D,Zhou X
Tue Feb 01 00:00:00 EST 2022
Activation of the NLRP3 inflammasome by RAC1 mediates a new mechanism in diabetic nephropathy.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Ying C,Zhou Z,Dai J,Wang M,Xiang J,Sun D,Zhou X
Tue Feb 01 00:00:00 EST 2022
Activation of the NLRP3 inflammasome by RAC1 mediates a new mechanism in diabetic nephropathy.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Ying C,Zhou Z,Dai J,Wang M,Xiang J,Sun D,Zhou X
Tue Feb 01 00:00:00 EST 2022
MicroRNA-223-3p promotes pyroptosis of cardiomyocyte and release of inflammasome factors via downregulating the expression level of SPI1 (PU.1).
Toxicology
Zhao S,Tan Y,Qin J,Xu H,Liu L,Wan H,Zhang C,Fan W,Qu S
Thu Jun 30 00:00:00 EDT 2022
4,5-Dimethoxycanthin-6-one is a novel LSD1 inhibitor that inhibits proliferation of glioblastoma cells and induces apoptosis and pyroptosis.
Cancer cell international
Li W,Huang BS,Xiong YY,Yang LJ,Wu LX
Tue Jan 18 00:00:00 EST 2022
Tetrahydrocurcumin improves lipopolysaccharide-induced myocardial dysfunction by inhibiting oxidative stress and inflammation via JNK/ERK signaling pathway regulation.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhu H,Zhang L,Jia H,Xu L,Cao Y,Zhai M,Li K,Xia L,Jiang L,Li X,Zhou Y,Liu J,Yu S,Duan W
Thu Sep 01 00:00:00 EDT 2022
The Clostridium Metabolite P-Cresol Sulfate Relieves Inflammation of Primary Biliary Cholangitis by Regulating Kupffer Cells.
Cells
Fu HY,Xu JM,Ai X,Dang FT,Tan X,Yu HY,Feng J,Yang WX,Ma HT,Tu RF,Gupta AK,Manandhar LK,Bao WM,Tang YM
Sat Nov 26 00:00:00 EST 2022
IL-17A drives cognitive aging probably via inducing neuroinflammation and theta oscillation disruption in the hippocampus.
International immunopharmacology
Li Y,Mao M,Zhu L,Sun Q,Tong J,Zhou Z
Fri Jul 01 00:00:00 EDT 2022
Macrophage SCAP Contributes to Metaflammation and Lean NAFLD by Activating STING-NF-κB Signaling Pathway.
Cellular and molecular gastroenterology and hepatology
Huang X,Yao Y,Hou X,Wei L,Rao Y,Su Y,Zheng G,Ruan XZ,Li D,Chen Y
Mon Jun 20 00:00:00 EDT 2022
Integrated single-cell transcriptomics and proteomics reveal cellular-specific responses and microenvironment remodeling in aristolochic acid nephropathy.
JCI insight
Chen J,Luo P,Wang C,Yang C,Bai Y,He X,Zhang Q,Zhang J,Yang J,Wang S,Wang J
Mon Aug 22 00:00:00 EDT 2022
The role of APTX4870 peptide in reducing cellular inflammatory responses by inhibiting Mycobacterium tuberculosis-derived mycolic acid-induced cytotoxicity.
Frontiers in microbiology
Lin X,Jia W,Feng G,Su Y,Kang Y,Zhang C,Liu W,Lu Z,Xue D
Fri Nov 11 00:00:00 EST 2022
The role of APTX4870 peptide in reducing cellular inflammatory responses by inhibiting Mycobacterium tuberculosis-derived mycolic acid-induced cytotoxicity.
Frontiers in microbiology
Lin X,Jia W,Feng G,Su Y,Kang Y,Zhang C,Liu W,Lu Z,Xue D
Fri Nov 11 00:00:00 EST 2022
Apelin-13 reduces lipopolysaccharide-induced neuroinflammation and cognitive impairment via promoting glucocorticoid receptor expression and nuclear translocation.
Neuroscience letters
Hu S,Shen P,Chen B,Tian SW,You Y
Sun Sep 25 00:00:00 EDT 2022
Fecal microbiota transplantation ameliorates bone loss in mice with ovariectomy-induced osteoporosis via modulating gut microbiota and metabolic function.
Journal of orthopaedic translation
Zhang YW,Cao MM,Li YJ,Lu PP,Dai GC,Zhang M,Wang H,Rui YF
Tue Nov 01 00:00:00 EDT 2022
Fecal microbiota transplantation ameliorates bone loss in mice with ovariectomy-induced osteoporosis via modulating gut microbiota and metabolic function.
Journal of orthopaedic translation
Zhang YW,Cao MM,Li YJ,Lu PP,Dai GC,Zhang M,Wang H,Rui YF
Tue Nov 01 00:00:00 EDT 2022
Capsaicin ameliorates inflammation in a TRPV1-independent mechanism by inhibiting PKM2-LDHA-mediated Warburg effect in sepsis.
Cell chemical biology
Zhang Q,Luo P,Xia F,Tang H,Chen J,Zhang J,Liu D,Zhu Y,Liu Y,Gu L,Zheng L,Li Z,Yang F,Dai L,Liao F,Xu C,Wang J
Thu Aug 18 00:00:00 EDT 2022
Schisandra chinensis Lignans Exert Antidepressant Effects by Promoting BV2 Microglia Polarization toward the M2 Phenotype through the Activation of the Cannabinoid Receptor Type-2-Signal Transducer and Activator of Transcription 6 Pathway.
Journal of agricultural and food chemistry
Wang J,Zhang G,Yang Y,Zhang X,Shi K,Zhang X,Yan T,Jia Y
Wed Nov 09 00:00:00 EST 2022
Hypoxia-Activated Prodrugs with Dual COX-2/CA Inhibitory Effects on Attenuating Cardiac Inflammation under Hypoxia.
Journal of medicinal chemistry
Zhou W,Wang C,Liu Z,Gou S
Thu Oct 13 00:00:00 EDT 2022
SARS-CoV-2 infection triggers paracrine senescence and leads to a sustained senescence-associated inflammatory response.
Nature aging
Tsuji S,Minami S,Hashimoto R,Konishi Y,Suzuki T,Kondo T,Sasai M,Torii S,Ono C,Shichinohe S,Sato S,Wakita M,Okumura S,Nakano S,Matsudaira T,Matsumoto T,Kawamoto S,Yamamoto M,Watanabe T,Matsuura Y,Takayama K,Kobayashi T,Okamoto T,Hara E
Tue Feb 01 00:00:00 EST 2022
Mild inflammation persists in the glenohumeral joint of patients with shoulder instability: Cross-sectional study.
Osteoarthritis and cartilage open
Muneshige K,Kenmoku T,Uchida K,Arendt-Nielsen L,Tazawa R,Nakawaki M,Ishii D,Satoh M,Inoue G,Takaso M
Wed Jun 01 00:00:00 EDT 2022
Time-dependent alterations in the rat nigrostriatal system after intrastriatal injection of fibrils formed by α-Syn and tau fragments.
Frontiers in aging neuroscience
Yang X,Wang J,Zeng W,Zhang X,Yang X,Xu Y,Xu Y,Cao X
Wed Dec 21 00:00:00 EST 2022
Time-dependent alterations in the rat nigrostriatal system after intrastriatal injection of fibrils formed by α-Syn and tau fragments.
Frontiers in aging neuroscience
Yang X,Wang J,Zeng W,Zhang X,Yang X,Xu Y,Xu Y,Cao X
Wed Dec 21 00:00:00 EST 2022
Targeted inhibition of the immunoproteasome blocks endothelial MHC class II antigen presentation to CD4+ T cells in chronic liver injury.
International immunopharmacology
Zhang Y,Yang X,Bi T,Wu X,Wang L,Ren Y,Ou Y,Xie C,Li K,Ran H,Wang J,Zhao F,Shui P,Qing J
Wed Jun 01 00:00:00 EDT 2022
Anti-inflammatory potential of stevia residue extract against uric acid-associated renal injury in mice.
Journal of food biochemistry
Mehmood A,Althobaiti F,Zhao L,Usman M,Chen X,Alharthi F,Soliman MM,Shah AA,Murtaza MA,Nadeem M,Ranjha MMAN,Wang C
Sat Oct 01 00:00:00 EDT 2022
Anti-inflammatory potential of stevia residue extract against uric acid-associated renal injury in mice.
Journal of food biochemistry
Mehmood A,Althobaiti F,Zhao L,Usman M,Chen X,Alharthi F,Soliman MM,Shah AA,Murtaza MA,Nadeem M,Ranjha MMAN,Wang C
Sat Oct 01 00:00:00 EDT 2022
Reduced inhibition underlies early life LPS exposure induced-cognitive impairment: Prevention by environmental enrichment.
International immunopharmacology
Wu XM,Ji MH,Yin XY,Gu HW,Zhu TT,Wang RZ,Yang JJ,Shen JC
Fri Jul 01 00:00:00 EDT 2022
Dissection of cellular and molecular mechanisms of aristolochic acid-induced hepatotoxicity via single-cell transcriptomics.
Precision clinical medicine
Luo P,Chen J,Zhang Q,Xia F,Wang C,Bai Y,Tang H,Liu D,Gu L,Du Q,Xiao W,Yang C,Wang J
Thu Dec 01 00:00:00 EST 2022
NLRP3 inflammasome contributes to endothelial dysfunction in angiotensin II-induced hypertension in mice.
Microvascular research
Li X,Zhang Z,Luo M,Cheng Z,Wang R,Liu Q,Lv D,Yan J,Shang F,Luo S,Xia Y
Thu Sep 01 00:00:00 EDT 2022
Rescuing ischemic stroke by biomimetic nanovesicles through accelerated thrombolysis and sequential ischemia-reperfusion protection.
Acta biomaterialia
Yu W,Yin N,Yang Y,Xuan C,Liu X,Liu W,Zhang Z,Zhang K,Liu J,Shi J
Tue Mar 01 00:00:00 EST 2022
Effect of Lactobacillus with Feruloyl Esterase-Producing Ability on Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice.
Journal of agricultural and food chemistry
Shen D,Ma S,Li X,Lu Y
Wed Nov 30 00:00:00 EST 2022
HSPB8 Overexpression Ameliorates Cognitive Impairment in Diabetic Mice via Inhibiting NLRP3 Inflammation Activation.
Oxidative medicine and cellular longevity
Chang Y,Wu Y,Jiang X,Zhu J,Wang C,Ma R,Li G
Mon Aug 15 00:00:00 EDT 2022
A novel Atlantic salmon (Salmo salar) bone collagen peptide delays osteoarthritis development by inhibiting cartilage matrix degradation and anti-inflammatory.
Food research international (Ottawa, Ont.)
Luo X,Liu W,Zhao M,Liu T,Xiong F,Lei L,Jia F,Feng F
Thu Dec 01 00:00:00 EST 2022
Tongluo Yishen Decoction Ameliorates Renal Fibrosis via NLRP3-Mediated Pyroptosis In Vivo and In Vitro.
Frontiers in pharmacology
Jia Q,Zhang X,Hao G,Zhao Y,Lowe S,Han L,Qin J
Tue Jul 26 00:00:00 EDT 2022
Negative Feedback of the cAMP/PKA Pathway Regulates the Effects of Endoplasmic Reticulum Stress-Induced NLRP3 Inflammasome Activation on Type II Alveolar Epithelial Cell Pyroptosis as a Novel Mechanism of BLM-Induced Pulmonary Fibrosis.
Journal of immunology research
Hong Q,Zhang Y,Lin W,Wang W,Yuan Y,Lin J,Xie Z,Li X,Meng Y
Tue Aug 30 00:00:00 EDT 2022
Negative Feedback of the cAMP/PKA Pathway Regulates the Effects of Endoplasmic Reticulum Stress-Induced NLRP3 Inflammasome Activation on Type II Alveolar Epithelial Cell Pyroptosis as a Novel Mechanism of BLM-Induced Pulmonary Fibrosis.
Journal of immunology research
Hong Q,Zhang Y,Lin W,Wang W,Yuan Y,Lin J,Xie Z,Li X,Meng Y
Tue Aug 30 00:00:00 EDT 2022
Negative Feedback of the cAMP/PKA Pathway Regulates the Effects of Endoplasmic Reticulum Stress-Induced NLRP3 Inflammasome Activation on Type II Alveolar Epithelial Cell Pyroptosis as a Novel Mechanism of BLM-Induced Pulmonary Fibrosis.
Journal of immunology research
Hong Q,Zhang Y,Lin W,Wang W,Yuan Y,Lin J,Xie Z,Li X,Meng Y
Tue Aug 30 00:00:00 EDT 2022
Synthesis and anti-inflammatory activity of paeonol derivatives with etherized aryl urea by regulating TLR4/MyD88 signaling pathway in RAW264.7 cell.
Bioorganic chemistry
Gong X,He Y,Yang D,Yang S,Li J,Zhao H,Chen Q,Ren Q,Zhang B
Sat Oct 01 00:00:00 EDT 2022
Methionine strengthens anti-inflammation of rice protein via depressing NF-κB activation and stimulating Msr expression in rats fed cholesterol-enriched diets.
Food science and biotechnology
Wang Z,Liang M,Liu B,Yang L
Wed Jun 01 00:00:00 EDT 2022
Cyanidin Chloride Improves LPS-Induced Depression-Like Behavior in Mice by Ameliorating Hippocampal Inflammation and Excitotoxicity.
ACS chemical neuroscience
Qu D,Ye Z,Zhang W,Dai B,Chen G,Wang L,Shao X,Xiang A,Lu Z,Shi J
Wed Nov 02 00:00:00 EDT 2022
LncRNA FAF attenuates hypoxia/ischaemia-induced pyroptosis via the miR-185-5p/PAK2 axis in cardiomyocytes.
Journal of cellular and molecular medicine
Gu J,Shi JZ,Wang YX,Liu L,Wang SB,Sun JT,Shan TK,Wang H,Wang QM,Wang LS
Sun May 01 00:00:00 EDT 2022
Identification of pyroptosis-related lncRNA signature and AC005253.1 as a pyroptosis-related oncogene in prostate cancer.
Frontiers in oncology
Yu J,Tang R,Li J
Wed Oct 19 00:00:00 EDT 2022
Tri-n-butyl phosphate delays tissue repair by dysregulating neutrophil function in zebrafish.
Toxicology and applied pharmacology
Wang Y,Cheng Z,Zhang H,Li S,Pan Y,Zhang W,Huang S,He X,Zou F,Yuan Z,Yan W,Huang H
Mon Aug 15 00:00:00 EDT 2022
Placental trophoblast-specific overexpression of chemerin induces preeclampsia-like symptoms.
Clinical science (London, England : 1979)
Tan L,Chen Z,Sun F,Zhou Z,Zhang B,Wang B,Chen J,Li M,Xiao T,Neuman RI,Niu J,Verdonk K,Lu X,Zhang JV,Danser AHJ,Yang Q,Fan X
Fri Feb 25 00:00:00 EST 2022
Sinapic Acid Alleviates Acute Pancreatitis in Association with Attenuation of Inflammation, Pyroptosis, and the AMPK/NF-[Formula: see text]B Signaling Pathway.
The American journal of Chinese medicine
Huang ZW,Tan P,Yi XK,Chen H,Sun B,Shi H,Mou ZQ,Cheng YL,Li TX,Li Q,Fu WG
Fri Nov 25 00:00:00 EST 2022
LncRNA TM1-3P Regulates Proliferation, Apoptosis and Inflammation of Fibroblasts in Osteoarthritis through miR-144-3p/ONECUT2 Axis.
Orthopaedic surgery
Yi Y,Yang N,Yang Z,Tao X,Li Y
Tue Nov 01 00:00:00 EDT 2022
Astaxanthin Activated the Nrf2/HO-1 Pathway to Enhance Autophagy and Inhibit Ferroptosis, Ameliorating Acetaminophen-Induced Liver Injury.
ACS applied materials & interfaces
Cai X,Hua S,Deng J,Du Z,Zhang D,Liu Z,Khan NU,Zhou M,Chen Z
Wed Sep 28 00:00:00 EDT 2022
Exploring the Mechanism of Hawthorn Leaves Against Coronary Heart Disease Using Network Pharmacology and Molecular Docking.
Frontiers in cardiovascular medicine
Ding J,Wu J,Wei H,Li S,Huang M,Wang Y,Fang Q
Sat Jul 16 00:00:00 EDT 2022
A Novel Rat Model of Dry Eye Induced by Aerosol Exposure of Particulate Matter.
Investigative ophthalmology & visual science
Mu N,Wang H,Chen D,Wang F,Ji L,Zhang C,Li M,Lu P
Mon Jan 03 00:00:00 EST 2022
Yishen Capsule Alleviated Symptoms of Diabetic Nephropathy via NOD-like Receptor Signaling Pathway.
Diabetes, metabolic syndrome and obesity : targets and therapy
Zhang Z,Hu Y,Liu W,Zhang X,Wang R,Li H,Sun D,Fang J
Fri Aug 05 00:00:00 EDT 2022
Inflamm-Aging-Related Cytokines of IL-17 and IFN-γ Accelerate Osteoclastogenesis and Periodontal Destruction.
Journal of immunology research
Tan J,Dai A,Pan L,Zhang L,Wang Z,Ke T,Sun W,Wu Y,Ding PH,Chen L
Mon Jan 10 00:00:00 EST 2022
Berberine Protects against TNF-α-Induced Injury of Human Umbilical Vein Endothelial Cells via the AMPK/NF-κB/YY1 Signaling Pathway.
Evidence-based complementary and alternative medicine : eCAM
Chen L,Fan XD,Qu H,Bai RN,Shi DZ
Tue Jan 11 00:00:00 EST 2022
Salidroside Ameliorates Alzheimer's Disease by Targeting NLRP3 Inflammasome-Mediated Pyroptosis.
Frontiers in aging neuroscience
Cai Y,Chai Y,Fu Y,Wang Y,Zhang Y,Zhang X,Zhu L,Miao M,Yan T
Tue Feb 08 00:00:00 EST 2022
Renoprotective effects of levosimendan on acute kidney injury following cardiac arrest via anti-inflammation, anti-apoptosis, and ERK activation.
FEBS open bio
Tian L,Wang S,Zhao L,Lu X,Zhu C,Gong H,Yang W
Sun Aug 01 00:00:00 EDT 2021
Regulatory roles of miRNAs 16, 133a, and 223 on osteoclastic bone destruction caused by breast cancer metastasis.
International journal of oncology
Kitayama K,Kawamoto T,Kawakami Y,Hara H,Takemori T,Fujiwara S,Yahiro S,Miyamoto T,Mifune Y,Hoshino Y,Kakutani K,Matsumoto T,Matsushita T,Niikura T,Kuroda R,Akisue T
Mon Nov 01 00:00:00 EDT 2021
Procyanidin B2 alleviates liver injury caused by cold stimulation through Sonic hedgehog signalling and autophagy.
Journal of cellular and molecular medicine
Ma L,Li C,Lian S,Xu B,Lv H,Liu Y,Lu J,Ji H,Li S,Guo J,Yang H
Sun Aug 01 00:00:00 EDT 2021
miR‑4792 regulates inflammatory responses in Cryptococcus neoformans‑infected microglia.
International journal of molecular medicine
Yao G,Wang X,Wang Y,Hou Q,Gao R,Wang Y,Teng L,Lin W,Wang Z,Jin Y,Chen J
Mon Nov 01 00:00:00 EDT 2021
Pik3c3 deficiency in myeloid cells imparts partial resistance to experimental autoimmune encephalomyelitis associated with reduced IL-1β production.
Cellular & molecular immunology
Yang G,Song W,Xu J,Postoak JL,Cheng F,Martinez J,Zhang J,Wu L,Van Kaer L
Sun Aug 01 00:00:00 EDT 2021
Silenced microRNA-222 suppresses inflammatory response in gestational diabetes mellitus mice by promoting CXCR4.
Life sciences
Zhang H,Luan S,Xiao X,Lin L,Zhao X,Liu X
Mon Feb 01 00:00:00 EST 2021
A treatment combined prussian blue nanoparticles with low-intensity pulsed ultrasound alleviates cartilage damage in knee osteoarthritis by initiating PI3K/Akt/mTOR pathway.
American journal of translational research
Zuo D,Tan B,Jia G,Wu D,Yu L,Jia L
Tue Jun 22 00:00:00 EDT 2021
KCa3.1 Inhibition of Macrophages Suppresses Inflammatory Response Leading to Endothelial Damage in a Cell Model of Kawasaki Disease.
Journal of inflammation research
Zheng F,Tao Y,Liu J,Geng Z,Wang Y,Wang Y,Fu S,Wang W,Xie C,Zhang Y,Gong F
Thu Apr 21 00:00:00 EDT 2022
Dihydroartemisinin inhibits activation of the AIM2 inflammasome pathway and NF-κB/HIF-1α/VEGF pathway by inducing autophagy in A431 human cutaneous squamous cell carcinoma cells.
International journal of medical sciences
Wang Y,Li Z,Teng M,Liu J
Mon Dec 06 00:00:00 EST 2021
Cartilage endplate stem cells inhibit intervertebral disc degeneration by releasing exosomes to nucleus pulposus cells to activate Akt/autophagy.
Stem cells (Dayton, Ohio)
Luo L,Jian X,Sun H,Qin J,Wang Y,Zhang J,Shen Z,Yang D,Li C,Zhao P,Liu M,Tian Z,Zhou Y
Thu Apr 01 00:00:00 EDT 2021
CS-semi5 Inhibits NF-κB Activation to Block Synovial Inflammation, Cartilage Loss and Bone Erosion Associated With Collagen-Induced Arthritis.
Frontiers in pharmacology
Li X,Tang X,Wang Y,Chai C,Zhao Z,Zhang H,Peng Y,Wu L
Tue Jul 27 00:00:00 EDT 2021
Atractylodin Attenuates Dextran Sulfate Sodium-Induced Colitis by Alleviating Gut Microbiota Dysbiosis and Inhibiting Inflammatory Response Through the MAPK Pathway.
Frontiers in pharmacology
Qu L,Lin X,Liu C,Ke C,Zhou Z,Xu K,Cao G,Liu Y
Tue Aug 03 00:00:00 EDT 2021
c-FLIP regulates pyroptosis in retinal neurons following oxygen-glucose deprivation/recovery via a GSDMD-mediated pathway.
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft
Huang Y,Wang S,Huang F,Zhang Q,Qin B,Liao L,Wang M,Wan H,Yan W,Chen D,Liu F,Jiang B,Ji D,Xia X,Huang J,Xiong K
Sat May 01 00:00:00 EDT 2021
Extracellular vesicles derived from LPS-preconditioned human synovial mesenchymal stem cells inhibit extracellular matrix degradation and prevent osteoarthritis of the knee in a mouse model.
Stem cell research & therapy
Duan A,Shen K,Li B,Li C,Zhou H,Kong R,Shao Y,Qin J,Yuan T,Ji J,Guo W,Wang X,Xue T,Li L,Huang X,Sun Y,Cai Z,Liu W,Liu F
Wed Jul 28 00:00:00 EDT 2021
Chicoric acid attenuates hyperglycemia-induced endothelial dysfunction through AMPK-dependent inhibition of oxidative/nitrative stresses.
Journal of receptor and signal transduction research
Ma X,Zhang J,Wu Z,Wang X
Sun Aug 01 00:00:00 EDT 2021
A neutral polysaccharide from Ophiocordyceps lanpingensis restrains cisplatin-induced nephrotoxicity.
Food science & nutrition
Zhou S,Zhou Y,Yu J,Jiang L,Xiang Y,Wang J,Du Y,Cui X,Ge F
Thu Jul 01 00:00:00 EDT 2021
Cordyceps acid alleviates lung cancer in nude mice.
Journal of biochemical and molecular toxicology
Wang J,Chen H,Li W,Shan L
Mon Mar 01 00:00:00 EST 2021
Estrogen-Related Receptor γ Agonist DY131 Ameliorates Lipopolysaccharide-Induced Acute Liver Injury.
Frontiers in pharmacology
Ma H,Liu J,Du Y,Zhang S,Cao W,Jia Z,Gong W,Zhang A
Thu May 13 00:00:00 EDT 2021
Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice.
Frontiers in neuroscience
Chang Y,Yao Y,Ma R,Wang Z,Hu J,Wu Y,Jiang X,Li L,Li G
Mon Jul 12 00:00:00 EDT 2021
Aspergillus fumigatus-Stimulated Human Corneal Epithelial Cells Induce Pyroptosis of THP-1 Macrophages by Secreting TSLP.
Inflammation
Ji Q,Wang L,Liu J,Wu Y,Lv H,Wen Y,Shi L,Qu B,Szentmáry N
Thu Apr 01 00:00:00 EDT 2021
Melatonin inhibits vascular endothelial cell pyroptosis by improving mitochondrial function via up-regulation and demethylation of UQCRC1.
Biochemistry and cell biology = Biochimie et biologie cellulaire
Zeng J,Tao J,Xia L,Zeng Z,Chen J,Wang Z,Meng J,Liu L
Tue Jun 01 00:00:00 EDT 2021
Assessment of Pyroptosis-Related Indicators as Potential Biomarkers and Their Association with Severity in Patients with Liver Cirrhosis.
Journal of inflammation research
Wang D,Zhan X,Wu R,You Y,Chen W,Duan L
Mon Apr 25 00:00:00 EDT 2022
Lactobacillus acidophilus ATCC 4356 Alleviates Renal Ischemia-Reperfusion Injury Through Antioxidant Stress and Anti-inflammatory Responses and Improves Intestinal Microbial Distribution.
Frontiers in nutrition
Zhang P,Han X,Zhang X,Zhu X
Sun May 30 00:00:00 EDT 2021
Salidroside inhibits NLRP3 inflammasome activation and apoptosis in microglia induced by cerebral ischemia/reperfusion injury by inhibiting the TLR4/NF-κB signaling pathway.
Annals of translational medicine
Liu J,Ma W,Zang CH,Wang GD,Zhang SJ,Wu HJ,Zhu KW,Xiang XL,Li CY,Liu KP,Guo JH,Li LY
Mon Nov 01 00:00:00 EDT 2021
Geniposide Combined With Notoginsenoside R1 Attenuates Inflammation and Apoptosis in Atherosclerosis via the AMPK/mTOR/Nrf2 Signaling Pathway.
Frontiers in pharmacology
Liu X,Xu Y,Cheng S,Zhou X,Zhou F,He P,Hu F,Zhang L,Chen Y,Jia Y
Tue Jul 27 00:00:00 EDT 2021
Extracellular CIRP Induces Macrophage Extracellular Trap Formation Via Gasdermin D Activation.
Frontiers in immunology
Lee Y,Reilly B,Tan C,Wang P,Aziz M
Mon Feb 14 00:00:00 EST 2022
Mesenchymal Stem Cells Overexpressing ACE2 Favorably Ameliorate LPS-Induced Inflammatory Injury in Mammary Epithelial Cells.
Frontiers in immunology
Yan S,Ye P,Aleem MT,Chen X,Xie N,Zhang Y
Thu Feb 24 00:00:00 EST 2022
Impaired autophagy in microglia aggravates dopaminergic neurodegeneration by regulating NLRP3 inflammasome activation in experimental models of Parkinson's disease.
Brain, behavior, and immunity
Qin Y,Qiu J,Wang P,Liu J,Zhao Y,Jiang F,Lou H
Fri Jan 01 00:00:00 EST 2021
The Protective Role of Yin-Yang 1 in Cardiac Injury and Remodeling After Myocardial Infarction.
Journal of the American Heart Association
Huang Y,Li L,Chen H,Liao Q,Yang X,Yang D,Xia X,Wang H,Wang WE,Chen L,Zeng C
Tue Nov 02 00:00:00 EDT 2021
Prototheca spp. induce an inflammatory response via mtROS-mediated activation of NF-κB and NLRP3 inflammasome pathways in bovine mammary epithelial cell cultures.
Veterinary research
Zhao W,He F,Barkema HW,Xu S,Gao J,Liu G,Deng Z,Shahid M,Shi Y,Kastelic JP,Han B
Sat Dec 11 00:00:00 EST 2021
The cardioprotective effect of the sodium-glucose cotransporter 2 inhibitor dapagliflozin in rats with isoproterenol-induced cardiomyopathy.
American journal of translational research
Wang FZ,Wei WB,Li X,Huo JY,Jiang WY,Wang HY,Qian P,Li ZZ,Zhou YB
Sat Oct 16 00:00:00 EDT 2021
Maternal immune activation alters adult behavior, intestinal integrity, gut microbiota and the gut inflammation.
Brain and behavior
Li W,Chen M,Feng X,Song M,Shao M,Yang Y,Zhang L,Liu Q,Lv L,Su X
Sat May 01 00:00:00 EDT 2021
Aging-associated lncRNAs are evolutionarily conserved and participate in NFκB signaling.
Nature aging
Cai D,Han JJ
Sat May 01 00:00:00 EDT 2021
Aging-associated lncRNAs are evolutionarily conserved and participate in NFκB signaling.
Nature aging
Cai D,Han JJ
Sat May 01 00:00:00 EDT 2021
JQ1 as a BRD4 Inhibitor Blocks Inflammatory Pyroptosis-Related Acute Colon Injury Induced by LPS.
Frontiers in immunology
Chen L,Zhong X,Cao W,Mao M,Li W,Yang H,Li M,Shi M,Zhang Y,Deng Y,Zu X,Liu J
Fri Jul 02 00:00:00 EDT 2021
Traditional Chinese Medication Qiliqiangxin Attenuates Diabetic Cardiomyopathy via Activating PPARγ.
Frontiers in cardiovascular medicine
Wu X,Zhang T,Lyu P,Chen M,Ni G,Cheng H,Xu G,Li X,Wang L,Shang H
Tue Aug 03 00:00:00 EDT 2021
Highly specific and label-free histological identification of microcrystals in fresh human gout tissues with stimulated Raman scattering.
Theranostics
Zhang B,Xu H,Chen J,Zhu X,Xue Y,Yang Y,Ao J,Hua Y,Ji M
Tue Jul 27 00:00:00 EDT 2021
Ameliorative effects of Schisandrin B on Schistosoma mansoni-induced hepatic fibrosis in vivo.
PLoS neglected tropical diseases
Lam HYP,Liang TR,Peng SY
Tue Jun 01 00:00:00 EDT 2021
Gasdermin D Protects Mouse Podocytes Against High-Glucose-Induced Inflammation and Apoptosis via the C-Jun N-Terminal Kinase (JNK) Pathway.
Medical science monitor : international medical journal of experimental and clinical research
Li H,Zhao K,Li Y
Tue Mar 09 00:00:00 EST 2021
Adrenomedullin Attenuates Inflammation in White Adipose Tissue of Obese Rats Through Receptor-Mediated PKA Pathway.
Obesity (Silver Spring, Md.)
Dai HB,Wang FZ,Kang Y,Sun J,Zhou H,Gao Q,Li ZZ,Qian P,Zhu GQ,Zhou YB
Fri Jan 01 00:00:00 EST 2021
Endogenous hydrogen sulfide improves vascular remodeling through PPARδ/SOCS3 signaling.
Journal of advanced research
Tian D,Teng X,Jin S,Chen Y,Xue H,Xiao L,Wu Y
Fri Jan 01 00:00:00 EST 2021
Anti-NAFLD Effect of Djulis Hull and Its Major Compound, Rutin, in Mice with High-Fat Diet (HFD)-Induced Obesity.
Antioxidants (Basel, Switzerland)
Tung YT,Zeng JL,Ho ST,Xu JW,Li S,Wu JH
Wed Oct 27 00:00:00 EDT 2021
Isoorientin Attenuated the Pyroptotic Hepatocyte Damage Induced by Benzo[a]pyrene via ROS/NF-κB/NLRP3/Caspase-1 Signaling Pathway.
Antioxidants (Basel, Switzerland)
Li H,Yuan L,Li X,Luo Y,Zhang Z,Li J
Wed Aug 11 00:00:00 EDT 2021
Indole-3-Propionic Acid, a Functional Metabolite of Clostridium sporogenes, Promotes Muscle Tissue Development and Reduces Muscle Cell Inflammation.
International journal of molecular sciences
Du L,Qi R,Wang J,Liu Z,Wu Z
Thu Nov 18 00:00:00 EST 2021
Indole-3-Propionic Acid, a Functional Metabolite of Clostridium sporogenes, Promotes Muscle Tissue Development and Reduces Muscle Cell Inflammation.
International journal of molecular sciences
Du L,Qi R,Wang J,Liu Z,Wu Z
Thu Nov 18 00:00:00 EST 2021
Dl-3-n-Butylphthalide Rescues Dopaminergic Neurons in Parkinson's Disease Models by Inhibiting the NLRP3 Inflammasome and Ameliorating Mitochondrial Impairment.
Frontiers in immunology
Que R,Zheng J,Chang Z,Zhang W,Li H,Xie Z,Huang Z,Wang HT,Xu J,Jin D,Yang W,Tan EK,Wang Q
Fri Mar 04 00:00:00 EST 2022
Dl-3-n-Butylphthalide Rescues Dopaminergic Neurons in Parkinson's Disease Models by Inhibiting the NLRP3 Inflammasome and Ameliorating Mitochondrial Impairment.
Frontiers in immunology
Que R,Zheng J,Chang Z,Zhang W,Li H,Xie Z,Huang Z,Wang HT,Xu J,Jin D,Yang W,Tan EK,Wang Q
Fri Mar 04 00:00:00 EST 2022
Dl-3-n-Butylphthalide Rescues Dopaminergic Neurons in Parkinson's Disease Models by Inhibiting the NLRP3 Inflammasome and Ameliorating Mitochondrial Impairment.
Frontiers in immunology
Que R,Zheng J,Chang Z,Zhang W,Li H,Xie Z,Huang Z,Wang HT,Xu J,Jin D,Yang W,Tan EK,Wang Q
Fri Mar 04 00:00:00 EST 2022
Dl-3-n-Butylphthalide Rescues Dopaminergic Neurons in Parkinson's Disease Models by Inhibiting the NLRP3 Inflammasome and Ameliorating Mitochondrial Impairment.
Frontiers in immunology
Que R,Zheng J,Chang Z,Zhang W,Li H,Xie Z,Huang Z,Wang HT,Xu J,Jin D,Yang W,Tan EK,Wang Q
Fri Mar 04 00:00:00 EST 2022
Oridonin Alleviates LPS-Induced Depression by Inhibiting NLRP3 Inflammasome via Activation of Autophagy.
Frontiers in medicine
Li C,Zhu Y,Wu Y,Fu M,Wu Y,Wu Y,Qiu Y,Zhang H,Ding M
Tue Feb 01 00:00:00 EST 2022
Kartogenin prevents cartilage degradation and alleviates osteoarthritis progression in mice via the miR-146a/NRF2 axis.
Cell death & disease
Hou M,Zhang Y,Zhou X,Liu T,Yang H,Chen X,He F,Zhu X
Thu May 13 00:00:00 EDT 2021
Ginsenoside Rg3 attenuates cisplatin-induced kidney injury through inhibition of apoptosis and autophagy-inhibited NLRP3.
Journal of biochemical and molecular toxicology
Zhai J,Gao H,Wang S,Zhang S,Qu X,Zhang Y,Tao L,Sun J,Song Y,Fu L
Mon Nov 01 00:00:00 EDT 2021
Circ_0001438 participates in the pathogenesis of preeclampsia via the circ_0001438/miR-942/NLRP3 regulatory network.
Placenta
Li X,Yang R,Xu Y,Zhang Y
Fri Jan 15 00:00:00 EST 2021
Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Secreted by BMSCs Regulates Activated Astrocytes by Inhibiting NF-κB Signaling Pathway to Ameliorate Blood Brain Barrier Damage After Intracerebral Hemorrhage.
Neurochemical research
Tang B,Song M,Xie X,Le D,Tu Q,Wu X,Chen M
Wed Sep 01 00:00:00 EDT 2021
Loss of Arf Guanine Nucleotide Exchange Factor GBF1 Activity Disturbs Organelle Dynamics in Mouse Oocytes.
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada
Zou YJ,Shan MM,Pan ZN,Pan MH,Li XH,Sun SC
Thu Apr 01 00:00:00 EDT 2021
F-Box Protein FBXW17-Mediated Proteasomal Degradation of Protein Methyltransferase PRMT6 Exaggerates CSE-Induced Lung Epithelial Inflammation and Apoptosis.
Frontiers in cell and developmental biology
Li T,He X,Luo L,Zeng H,Ren S,Chen Y
Sat May 08 00:00:00 EDT 2021
Long-term ketamine administration induces bladder damage and upregulates autophagy-associated proteins in bladder smooth muscle tissue.
Environmental toxicology
Li Y,Dong Z,Wen G,Ren X,Ren W,Yan L,Wang X,Yu H,Wu X,Xia X,Lu Y,Wu X
Wed Dec 01 00:00:00 EST 2021
Suppressing ROS generation by apocynin inhibited cyclic stretch-induced inflammatory reaction in HPDLCs via a caspase-1 dependent pathway.
International immunopharmacology
Wang Y,Song Y,Zhong Q,Wu Y,Zhuang J,Qu F,Xu C
Fri Jan 01 00:00:00 EST 2021
Study on Protection of Human Umbilical Vein Endothelial Cells from Amiodarone-Induced Damage by Intermedin through Activation of Wnt/β-Catenin Signaling Pathway.
Oxidative medicine and cellular longevity
Wang Y,Wang J,Yang J,Kang J,Xue F,Chang S,Ji H,Zang H,Zhou X,Wang G,Fan W,Yan X,Guo J,Ren X,Tian J
Wed Jan 19 00:00:00 EST 2022
AICAR, an AMP-Activated Protein Kinase Activator, Ameliorates Acute Pancreatitis-Associated Liver Injury Partially Through Nrf2-Mediated Antioxidant Effects and Inhibition of NLRP3 Inflammasome Activation.
Frontiers in pharmacology
Kong L,Zhang H,Lu C,Shi K,Huang H,Zheng Y,Wang Y,Wang D,Wang H,Huang W
Sat Sep 18 00:00:00 EDT 2021
AICAR, an AMP-Activated Protein Kinase Activator, Ameliorates Acute Pancreatitis-Associated Liver Injury Partially Through Nrf2-Mediated Antioxidant Effects and Inhibition of NLRP3 Inflammasome Activation.
Frontiers in pharmacology
Kong L,Zhang H,Lu C,Shi K,Huang H,Zheng Y,Wang Y,Wang D,Wang H,Huang W
Sat Sep 18 00:00:00 EDT 2021
AICAR, an AMP-Activated Protein Kinase Activator, Ameliorates Acute Pancreatitis-Associated Liver Injury Partially Through Nrf2-Mediated Antioxidant Effects and Inhibition of NLRP3 Inflammasome Activation.
Frontiers in pharmacology
Kong L,Zhang H,Lu C,Shi K,Huang H,Zheng Y,Wang Y,Wang D,Wang H,Huang W
Sat Sep 18 00:00:00 EDT 2021
AICAR, an AMP-Activated Protein Kinase Activator, Ameliorates Acute Pancreatitis-Associated Liver Injury Partially Through Nrf2-Mediated Antioxidant Effects and Inhibition of NLRP3 Inflammasome Activation.
Frontiers in pharmacology
Kong L,Zhang H,Lu C,Shi K,Huang H,Zheng Y,Wang Y,Wang D,Wang H,Huang W
Sat Sep 18 00:00:00 EDT 2021
Restoring microRNA-499-5p Protects Sepsis-Induced Lung Injury Mice Via Targeting Sox6.
Nanoscale research letters
Zhang W,Li J,Yao H,Li T
Fri May 21 00:00:00 EDT 2021
H2S alleviates aortic aneurysm and dissection: Crosstalk between transforming growth factor 1 signaling and NLRP3 inflammasome.
International journal of cardiology
Cui J,Xu G,Bian F
Wed Sep 01 00:00:00 EDT 2021
H2S alleviates aortic aneurysm and dissection: Crosstalk between transforming growth factor 1 signaling and NLRP3 inflammasome.
International journal of cardiology
Cui J,Xu G,Bian F
Wed Sep 01 00:00:00 EDT 2021
H2S alleviates aortic aneurysm and dissection: Crosstalk between transforming growth factor 1 signaling and NLRP3 inflammasome.
International journal of cardiology
Cui J,Xu G,Bian F
Wed Sep 01 00:00:00 EDT 2021
H2S alleviates aortic aneurysm and dissection: Crosstalk between transforming growth factor 1 signaling and NLRP3 inflammasome.
International journal of cardiology
Cui J,Xu G,Bian F
Wed Sep 01 00:00:00 EDT 2021
Benefit Effect of Dendrobium officinale Ultrafine Powder on DSS-Induced Ulcerative Colitis Rats by Improving Colon Mucosal Barrier.
Evidence-based complementary and alternative medicine : eCAM
Zheng X,Xiong TX,Zhang K,Zhou FC,Wang HY,Li B,Dong YJ,He X,Li LZ,Yu QX,Lv GY,Chen SH
Fri Apr 29 00:00:00 EDT 2022
Active components from Lagotis brachystachya maintain uric acid homeostasis by inhibiting renal TLR4-NLRP3 signaling in hyperuricemic mice.
Inflammopharmacology
Zhu JX,Yang HY,Hu WQ,Cheng J,Liu Y,Yi LT,Cheng HY
Sun Aug 01 00:00:00 EDT 2021
The Protective Effects of Zornia diphylla (L.) Pers. Against Acute Liver Injury Induced by Carbon Tetrachloride in Mice.
Frontiers in pharmacology
Xie SZ,Zhai XY,Xi SY,Qiu YK,Zhang YM,Kong XJ,Li YH,Zhu L,Wang Z,Zhang SG,Huang SQ,Lu DW,Wang Z
Wed Dec 15 00:00:00 EST 2021
PCSK9 mediates the oxidative low‑density lipoprotein‑induced pyroptosis of vascular endothelial cells via the UQCRC1/ROS pathway.
International journal of molecular medicine
Zeng J,Tao J,Xi L,Wang Z,Liu L
Thu Apr 01 00:00:00 EDT 2021
Low-intensity pulsed ultrasound ameliorates angiotensin II-induced cardiac fibrosis by alleviating inflammation via a caveolin-1-dependent pathway.
Journal of Zhejiang University. Science. B
Zhao K,Zhang J,Xu T,Yang C,Weng L,Wu T,Wu X,Miao J,Guo X,Tu J,Zhang D,Zhou B,Sun W,Kong X
Fri Oct 15 00:00:00 EDT 2021
Therapeutic targets of rosuvastatin on heart failure and associated biological mechanisms: A study of network pharmacology and experimental validation.
European journal of pharmacology
Lian Z,Song JX,Yu SR,Su LN,Cui YX,Li SF,Lee CY,Liang HZ,Chen H
Mon Mar 15 00:00:00 EDT 2021
Curcumin inhibits the growth of liver cancer by impairing myeloid-derived suppressor cells in murine tumor tissues.
Oncology letters
Tian S,Liao L,Zhou Q,Huang X,Zheng P,Guo Y,Deng T,Tian X
Thu Apr 01 00:00:00 EDT 2021
Anti-HIV Activity of Cucurbitacin-D against Cigarette Smoke Condensate-Induced HIV Replication in the U1 Macrophages.
Viruses
Kodidela S,Sinha N,Kumar A,Kumar S
Thu May 27 00:00:00 EDT 2021
Adrenomedullin 2 attenuates LPS-induced inflammation in microglia cells by receptor-mediated cAMP-PKA pathway.
Neuropeptides
Sun J,Qian P,Kang Y,Dai HB,Wang FZ,Wang HY,Zhou H,Gao Q,Zhou YB
Mon Feb 01 00:00:00 EST 2021
CART mitigates oxidative stress and DNA damage in memory deficits of APP/PS1 mice via upregulating β‑amyloid metabolism‑associated enzymes.
Molecular medicine reports
Jiang H,Niu F,Zheng Y,Xu Y
Thu Apr 01 00:00:00 EDT 2021
(-)-Epicatechin ameliorates cigarette smoke-induced lung inflammation via inhibiting ROS/NLRP3 inflammasome pathway in rats with COPD.
Toxicology and applied pharmacology
Tian X,Xue Y,Xie G,Zhou Y,Xiao H,Ding F,Zhang M
Fri Oct 15 00:00:00 EDT 2021
MBD2 Mediates Septic AKI through Activation of PKCη/p38MAPK and the ERK1/2 Axis.
Molecular therapy. Nucleic acids
Xie Y,Liu B,Pan J,Liu J,Li X,Li H,Qiu S,Xiang X,Zheng P,Chen J,Yuan Y,Dong Z,Zhang D
Fri Mar 05 00:00:00 EST 2021
Histone deacetylase 2 regulates ULK1 mediated pyroptosis during acute liver failure by the K68 acetylation site.
Cell death & disease
Wang Y,Chen Q,Jiao F,Shi C,Pei M,Wang L,Gong Z
Mon Jan 11 00:00:00 EST 2021
Histone deacetylase 2 regulates ULK1 mediated pyroptosis during acute liver failure by the K68 acetylation site.
Cell death & disease
Wang Y,Chen Q,Jiao F,Shi C,Pei M,Wang L,Gong Z
Mon Jan 11 00:00:00 EST 2021
Histone deacetylase 2 regulates ULK1 mediated pyroptosis during acute liver failure by the K68 acetylation site.
Cell death & disease
Wang Y,Chen Q,Jiao F,Shi C,Pei M,Wang L,Gong Z
Mon Jan 11 00:00:00 EST 2021
Histone deacetylase 2 regulates ULK1 mediated pyroptosis during acute liver failure by the K68 acetylation site.
Cell death & disease
Wang Y,Chen Q,Jiao F,Shi C,Pei M,Wang L,Gong Z
Mon Jan 11 00:00:00 EST 2021
Microcystin-LR Induces NLRP3 Inflammasome Activation via FOXO1 Phosphorylation, Resulting in Interleukin-1β Secretion and Pyroptosis in Hepatocytes.
Toxicological sciences : an official journal of the Society of Toxicology
Zhang Y,Zhu P,Wu X,Yuan T,Su Z,Chen S,Zhou Y,Tao WA
Wed Jan 06 00:00:00 EST 2021
Chronic ethanol exposure induced depressive-like behavior in male C57BL/6 N mice by downregulating GluA1.
Physiology & behavior
Yao H,Shen H,Yu H,Wang C,Ding R,Lan X,Tash D,Wu X,Wang X,Zhang G
Sat May 15 00:00:00 EDT 2021
H2S improves doxorubicin-induced myocardial fibrosis by inhibiting oxidative stress and apoptosis via Keap1-Nrf2.
Technology and health care : official journal of the European Society for Engineering and Medicine
Li Y,Chandra TP,Song X,Nie L,Liu M,Yi J,Zheng X,Chu C,Yang J
Wed Aug 18 00:00:00 EDT 2021
Magnesium-L-threonate alleviate colonic inflammation and memory impairment in chronic-plus-binge alcohol feeding mice.
Brain research bulletin
Liu C,Cheng Y,Guo Y,Qian H
Wed Sep 01 00:00:00 EDT 2021
Sodium-Glucose Co-transporter-2 Inhibitor of Dapagliflozin Attenuates Myocardial Ischemia/Reperfusion Injury by Limiting NLRP3 Inflammasome Activation and Modulating Autophagy.
Frontiers in cardiovascular medicine
Yu YW,Que JQ,Liu S,Huang KY,Qian L,Weng YB,Rong FN,Wang L,Zhou YY,Xue YJ,Ji KT
Fri Jan 28 00:00:00 EST 2022
Minimally Invasive Embedding of Saturated MSU Induces Persistent Gouty Arthritis in Modified Rat Model.
BioMed research international
Xu HL,Li SK,Xue XA,Chen ZY,Hua YH
Tue Sep 28 00:00:00 EDT 2021
The relationship between liver pathological inflammation degree and pyroptosis in chronic hepatitis B patients.
Journal of medical virology
Wang Y,Li X,Chen Q,Jiao F,Shi C,Pei M,Wang L,Gong Z
Mon Nov 01 00:00:00 EDT 2021
Resveratrol attenuates radiation enteritis through the SIRT1/FOXO3a and PI3K/AKT signaling pathways.
Biochemical and biophysical research communications
Qin H,Zhang H,Zhang X,Zhang S,Zhu S,Wang H
Fri May 21 00:00:00 EDT 2021
Hypertonic saline mediates the NLRP3/IL-1β signaling axis in microglia to alleviate ischemic blood-brain barrier permeability by downregulating astrocyte-derived VEGF in rats.
CNS neuroscience & therapeutics
Wang QS,Ding HG,Chen SL,Liu XQ,Deng YY,Jiang WQ,Li Y,Huang LQ,Han YL,Wen MY,Wang MQ,Zeng HK
Thu Oct 01 00:00:00 EDT 2020
NR1D1 modulates synovial inflammation and bone destruction in rheumatoid arthritis.
Cell death & disease
Liu H,Zhu Y,Gao Y,Qi D,Zhao L,Zhao L,Liu C,Tao T,Zhou C,Sun X,Guo F,Xiao J
Tue Feb 18 00:00:00 EST 2020
Alda-1, an activator of ALDH2, ameliorates Achilles tendinopathy in cellular and mouse models.
Biochemical pharmacology
Liu YC,Wang HL,Huang YZ,Weng YH,Chen RS,Tsai WC,Yeh TH,Lu CS,Chen YL,Lin YW,Chen YJ,Hsu CC,Chiu CH,Chiu CC
Fri May 01 00:00:00 EDT 2020
Alda-1, an activator of ALDH2, ameliorates Achilles tendinopathy in cellular and mouse models.
Biochemical pharmacology
Liu YC,Wang HL,Huang YZ,Weng YH,Chen RS,Tsai WC,Yeh TH,Lu CS,Chen YL,Lin YW,Chen YJ,Hsu CC,Chiu CH,Chiu CC
Fri May 01 00:00:00 EDT 2020
Corneal epithelial injury-induced norepinephrine promotes Pseudomonas aeruginosa keratitis.
Experimental eye research
Ma X,Wang Q,Song F,Li Y,Li J,Dou S,Xie L,Zhou Q
Mon Jun 01 00:00:00 EDT 2020
ACPAs promote IL-1β production in rheumatoid arthritis by activating the NLRP3 inflammasome.
Cellular & molecular immunology
Dong X,Zheng Z,Lin P,Fu X,Li F,Jiang J,Zhu P
Sun Mar 01 00:00:00 EST 2020
Inhibition of the ox-LDL-Induced Pyroptosis by FGF21 of Human Umbilical Vein Endothelial Cells Through the TET2-UQCRC1-ROS Pathway.
DNA and cell biology
Chen JJ,Tao J,Zhang XL,Xia LZ,Zeng JF,Zhang H,Wei DH,Lv YC,Li GH,Wang Z
Wed Apr 01 00:00:00 EDT 2020
CX3CR1-microglia mediates neuroinflammation and blood pressure regulation in the nucleus tractus solitarii of fructose-induced hypertensive rats.
Journal of neuroinflammation
Ho CY,Lin YT,Chen HH,Ho WY,Sun GC,Hsiao M,Lu PJ,Cheng PW,Tseng CJ
Fri Jun 12 00:00:00 EDT 2020
Salvianic acid A alleviates chronic alcoholic liver disease by inhibiting HMGB1 translocation via down-regulating BRD4.
Journal of cellular and molecular medicine
Lan Y,Yan R,Shan W,Chu J,Sun R,Wang R,Zhao Y,Wang Z,Zhang N,Yao J
Sat Aug 01 00:00:00 EDT 2020
Obesity induces preadipocyte CD36 expression promoting inflammation via the disruption of lysosomal calcium homeostasis and lysosome function.
EBioMedicine
Luo X,Li Y,Yang P,Chen Y,Wei L,Yu T,Xia J,Ruan XZ,Zhao L,Chen Y
Mon Jun 01 00:00:00 EDT 2020
Trimethylamine N-oxide promotes apoE-/- mice atherosclerosis by inducing vascular endothelial cell pyroptosis via the SDHB/ROS pathway.
Journal of cellular physiology
Wu P,Chen J,Chen J,Tao J,Wu S,Xu G,Wang Z,Wei D,Yin W
Thu Oct 01 00:00:00 EDT 2020
Metformin effectively treats Tsc1 deletion-caused kidney pathology by upregulating AMPK phosphorylation.
Cell death discovery
Fang Y,Li F,Qi C,Mao X,Wang F,Zhao Z,Chen JK,Zhang Z,Wu H
Tue Sep 26 00:00:00 EDT 2023
Transcriptomic Analysis of Age-Associated Periventricular Lesions Reveals Dysregulation of the Immune Response.
International journal of molecular sciences
Fadul MM,Heath PR,Cooper-Knock J,Kurz JM,Al-Azzawi HA,Ali Z,Smith T,Matthews FE,Brayne C,Wharton SB,Simpson JE
Sun Oct 25 00:00:00 EDT 2020
Fucoidan inhibits tooth movement by promoting restorative macrophage polarization through the STAT3 pathway.
Journal of cellular physiology
Zhang S,Zhang H,Jin Z,Wang S,Wang Y,Zhu L,Sun W,Yan B
Tue Sep 01 00:00:00 EDT 2020
Maresin 1 mitigates concanavalin A-induced acute liver injury in mice by inhibiting ROS-mediated activation of NF-κB signaling.
Free radical biology & medicine
Zhang P,Yin Y,Wang T,Li W,Li C,Zeng X,Yang W,Zhang R,Tang Y,Shi L,Li R,Tao K
Sat Feb 01 00:00:00 EST 2020
Dendrobium Alkaloids Promote Neural Function After Cerebral Ischemia-Reperfusion Injury Through Inhibiting Pyroptosis Induced Neuronal Death in both In Vivo and In Vitro Models.
Neurochemical research
Liu D,Dong Z,Xiang F,Liu H,Wang Y,Wang Q,Rao J
Sat Feb 01 00:00:00 EST 2020
Critical Role of AdipoR1 in Regulating Th17 Cell Differentiation Through Modulation of HIF-1α-Dependent Glycolysis.
Frontiers in immunology
Zhang Q,Wang L,Jiang J,Lin S,Luo A,Zhao P,Tan W,Zhang M
Fri Apr 30 00:00:00 EDT 2021
α-synuclein promotes progression of Parkinson's disease by upregulating autophagy signaling pathway to activate NLRP3 inflammasome.
Experimental and therapeutic medicine
Wang X,Chi J,Huang D,Ding L,Zhao X,Jiang L,Yu Y,Gao F
Sat Feb 01 00:00:00 EST 2020
Caffeic Acid Phenethyl Ester Prevents Colitis-Associated Cancer by Inhibiting NLRP3 Inflammasome.
Frontiers in oncology
Dai G,Jiang Z,Sun B,Liu C,Meng Q,Ding K,Jing W,Ju W
Mon Sep 28 00:00:00 EDT 2020
Manganese Exposure Aggravates β-Amyloid Pathology by Microglial Activation.
Frontiers in aging neuroscience
Lin G,Li X,Cheng X,Zhao N,Zheng W
Sat Nov 28 00:00:00 EST 2020
Eicosapentaenoic acid prevents inflammation induced by acute cerebral infarction through inhibition of NLRP3 inflammasome activation.
Life sciences
Mo Z,Tang C,Li H,Lei J,Zhu L,Kou L,Li H,Luo S,Li C,Chen W,Zhang L
Sat Feb 01 00:00:00 EST 2020
TNF-α/HMGB1 inflammation signalling pathway regulates pyroptosis during liver failure and acute kidney injury.
Cell proliferation
Wang Y,Zhang H,Chen Q,Jiao F,Shi C,Pei M,Lv J,Zhang H,Wang L,Gong Z
Mon Jun 01 00:00:00 EDT 2020
Rhein Suppresses Neuroinflammation via Multiple Signaling Pathways in LPS-Stimulated BV2 Microglia Cells.
Evidence-based complementary and alternative medicine : eCAM
Zheng P,Tian X,Zhang W,Yang Z,Zhou J,Zheng J,Cui H,Tang T,Luo J,Wang Y
Mon Sep 28 00:00:00 EDT 2020
Rhein Suppresses Neuroinflammation via Multiple Signaling Pathways in LPS-Stimulated BV2 Microglia Cells.
Evidence-based complementary and alternative medicine : eCAM
Zheng P,Tian X,Zhang W,Yang Z,Zhou J,Zheng J,Cui H,Tang T,Luo J,Wang Y
Mon Sep 28 00:00:00 EDT 2020
Microglia polarization of hippocampus is involved in the mechanism of Apelin-13 ameliorating chronic water immersion restraint stress-induced depression-like behavior in rats.
Neuropeptides
Zhou S,Chen S,Xie W,Guo X,Zhao J
Mon Jun 01 00:00:00 EDT 2020
LncRNA GAS5 inhibits NLRP3 inflammasome activation-mediated pyroptosis in diabetic cardiomyopathy by targeting miR-34b-3p/AHR.
Cell cycle (Georgetown, Tex.)
Xu Y,Fang H,Xu Q,Xu C,Yang L,Huang C
Sun Nov 01 00:00:00 EDT 2020
17-Allylamino-Demethoxygeldanamycin Ameliorate Microthrombosis Via HSP90/RIP3/NLRP3 Pathway After Subarachnoid Hemorrhage in Rats.
Acta neurochirurgica. Supplement
Zuo Y,He T,Liao P,Zhuang K,Yan X,Liu F
Mon Oct 28 00:00:00 EDT 2019
Ablation of GSDMD Improves Outcome of Ischemic Stroke Through Blocking Canonical and Non-canonical Inflammasomes Dependent Pyroptosis in Microglia.
Frontiers in neurology
Wang K,Sun Z,Ru J,Wang S,Huang L,Ruan L,Lin X,Jin K,Zhuge Q,Yang S
Fri Dec 18 00:00:00 EST 2020
NLRP3 inflammasome-mediated microglial pyroptosis is critically involved in the development of post-cardiac arrest brain injury.
Journal of neuroinflammation
Chang Y,Zhu J,Wang D,Li H,He Y,Liu K,Wang X,Peng Y,Pan S,Huang K
Thu Jul 23 00:00:00 EDT 2020
Effect of C-phycocyanin on HDAC3 and miRNA-335 in Alzheimer's disease.
Translational neuroscience
Li Z,Gan L,Yan S,Yan Y,Huang W
Mon Apr 18 00:00:00 EDT 2022
Monotropein alleviates secondary liver injury in chronic colitis by regulating TLR4/NF-κB signaling and NLRP3 inflammasome.
European journal of pharmacology
Chen Y,Lu Y,Pei C,Liang J,Ding P,Chen S,Hou SZ
Tue Sep 15 00:00:00 EDT 2020
Infrapatellar fat pads participate in the development of knee osteoarthritis in obese patients via the activation of the NF‑κB signaling pathway.
International journal of molecular medicine
Duan L,Ma Y,Wang Y,Liu J,Tan Z,Wu Q,Wu Y,Yu X
Tue Dec 01 00:00:00 EST 2020
Akkermansia muciniphila promotes type H vessel formation and bone fracture healing by reducing gut permeability and inflammation.
Disease models & mechanisms
Liu JH,Yue T,Luo ZW,Cao J,Yan ZQ,Jin L,Wan TF,Shuai CJ,Wang ZG,Zhou Y,Xu R,Xie H
Tue Dec 01 00:00:00 EST 2020
Anti-human serum albumin autoantibody may be involved in the pathogenesis of autoimmune bullous skin diseases.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Qian H,Cao Y,Sun J,Zu J,Ma L,Zhou H,Tang X,Li Y,Yu H,Zhang M,Bai Y,Xu C,Ishii N,Hashimoto T,Li X
Mon Jun 01 00:00:00 EDT 2020
Angiostrongylus cantonensis activates inflammasomes in meningoencephalitic BALB/c mice.
Parasitology international
Lam HYP,Chen TT,Chen CC,Yang TH,Cheng PC,Peng SY
Sat Aug 01 00:00:00 EDT 2020
The Biomarker TCONS_00016233 Drives Septic AKI by Targeting the miR-22-3p/AIFM1 Signaling Axis.
Molecular therapy. Nucleic acids
Zhang P,Yi L,Qu S,Dai J,Li X,Liu B,Li H,Ai K,Zheng P,Qiu S,Li Y,Wang Y,Xiang X,Chai X,Dong Z,Zhang D
Fri Mar 06 00:00:00 EST 2020
Albendazole-Schisandrin B Co-Therapy on Angiostrongylus cantonensis-Induced Meningoencephalitis in Mice.
Biomolecules
Lam HYP,Liang TR,Jiang SJ,Peng SY
Sun Jul 05 00:00:00 EDT 2020
COMP in the Infrapatellar Fat Pad-Results of a Prospective Histological, Immunohistological, and Biochemical Case-Control Study.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Grevenstein D,Heilig J,Dargel J,Oppermann J,Eysel P,Brochhausen C,Niehoff A
Wed Apr 01 00:00:00 EDT 2020
FGF21 mitigates atherosclerosis via inhibition of NLRP3 inflammasome-mediated vascular endothelial cells pyroptosis.
Experimental cell research
Zeng Z,Zheng Q,Chen J,Tan X,Li Q,Ding L,Zhang R,Lin X
Sat Aug 15 00:00:00 EDT 2020
Porphyromonas gingivalis-Induced NLRP3 Inflammasome Activation and Its Downstream Interleukin-1β Release Depend on Caspase-4.
Frontiers in microbiology
Ding PH,Yang MX,Wang NN,Jin LJ,Dong Y,Cai X,Chen LL
Mon Sep 28 00:00:00 EDT 2020
Porphyromonas gingivalis-Induced NLRP3 Inflammasome Activation and Its Downstream Interleukin-1β Release Depend on Caspase-4.
Frontiers in microbiology
Ding PH,Yang MX,Wang NN,Jin LJ,Dong Y,Cai X,Chen LL
Mon Sep 28 00:00:00 EDT 2020
Pharmacological Inhibition of HDAC6 Attenuates NLRP3 Inflammatory Response and Protects Dopaminergic Neurons in Experimental Models of Parkinson's Disease.
Frontiers in aging neuroscience
Yan S,Wei X,Jian W,Qin Y,Liu J,Zhu S,Jiang F,Lou H,Zhang B
Thu Apr 14 00:00:00 EDT 2022
Detection of proteins associated with the pyroptosis signaling pathway in breast cancer tissues and their significance.
International journal of clinical and experimental pathology
Wu X,Mao X,Huang Y,Zhu Q,Guan J,Wu L
Wed Jul 15 00:00:00 EDT 2020
High- and low-virulent bovine Pasteurella multocida induced differential NLRP3 inflammasome activation and subsequent IL-1β secretion.
Veterinary microbiology
Fang R,Lei G,Jiang J,Du H,Liu Y,Lei Z,Ye C,Li N,Peng Y
Wed Apr 01 00:00:00 EDT 2020
Salidroside Decreases Atherosclerosis Plaque Formation via Inhibiting Endothelial Cell Pyroptosis.
Inflammation
Xing SS,Yang J,Li WJ,Li J,Chen L,Yang YT,Lei X,Li J,Wang K,Liu X
Wed Apr 01 00:00:00 EDT 2020
Peptidome analysis of umbilical cord mesenchymal stem cell (hUC-MSC) conditioned medium from preterm and term infants.
Stem cell research & therapy
Wang Y,Zhang L,Wu Y,Zhu R,Wang Y,Cao Y,Long W,Ji C,Wang H,You L
Wed Sep 23 00:00:00 EDT 2020
Protective effect of astaxanthin against La2O3 nanoparticles induced neurotoxicity by activating PI3K/AKT/Nrf-2 signaling in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Yuan L,Qu Y,Li Q,An T,Chen Z,Chen Y,Deng X,Bai D
Thu Oct 01 00:00:00 EDT 2020
Interleukin-1β-Induced Senescence Promotes Osteoblastic Transition of Vascular Smooth Muscle Cells.
Kidney & blood pressure research
Han L,Zhang Y,Zhang M,Guo L,Wang J,Zeng F,Xu D,Yin Z,Xu Y,Wang D,Zhou H
Wed Nov 04 00:00:00 EST 2020
La2O3 Nanoparticles Induce Reproductive Toxicity Mediated by the Nrf-2/ARE Signaling Pathway in Kunming Mice.
International journal of nanomedicine
Yuan L,Li Q,Bai D,Shang X,Hu F,Chen Z,An T,Chen Y,Zhang X
Thu Jul 23 00:00:00 EDT 2020
Blocking the LncRNA MALAT1/miR-224-5p/NLRP3 Axis Inhibits the Hippocampal Inflammatory Response in T2DM With OSA.
Frontiers in cellular neuroscience
Du P,Wang J,Han Y,Feng J
Mon Sep 28 00:00:00 EDT 2020
Role of Endoplasmic Reticulum Stress in Otitis Media.
Frontiers in genetics
Zhao H,Wang Y,Li B,Zheng T,Liu X,Hu BH,Che J,Zhao T,Chen J,Hatzoglou M,Zhang X,Fan Z,Zheng Q
Mon Sep 28 00:00:00 EDT 2020
The Differential Expression of Cytokines and Growth Factors After SMILE Compared With FS-LASIK in Rabbits.
Investigative ophthalmology & visual science
Liu L,Cheng W,Wu D,Chen L,Yu S,Zuo T,Zhang L,Yang K,Li H,Zhang H,Wei P,Ng ALK,Cheng GP,Woo VC,Yin J,Chiu K,Wang Y
Mon May 11 00:00:00 EDT 2020
Aging alters Hv1-mediated microglial polarization and enhances neuroinflammation after peripheral surgery.
CNS neuroscience & therapeutics
Zhang ZJ,Zheng XX,Zhang XY,Zhang Y,Huang BY,Luo T
Sun Mar 01 00:00:00 EST 2020
Mechanism investigation on Bisphenol S-induced oxidative stress and inflammation in murine RAW264.7 cells: The role of NLRP3 inflammasome, TLR4, Nrf2 and MAPK.
Journal of hazardous materials
Xie C,Ge M,Jin J,Xu H,Mao L,Geng S,Wu J,Zhu J,Li X,Zhong C
Wed Jul 15 00:00:00 EDT 2020
A research of STEAP1 regulated gastric cancer cell proliferation, migration and invasion in vitro and in vivos.
Journal of cellular and molecular medicine
Zhang Z,Hou WB,Zhang C,Tan YE,Zhang DD,An W,Pan SW,Wu WD,Chen QC,Xu HM
Tue Dec 01 00:00:00 EST 2020
LINC01116 promotes tumor proliferation and neutrophil recruitment via DDX5-mediated regulation of IL-1β in glioma cell.
Cell death & disease
Wang T,Cao L,Dong X,Wu F,De W,Huang L,Wan Q
Fri May 01 00:00:00 EDT 2020
Selenomethionine Suppressed TLR4/NF-κB Pathway by Activating Selenoprotein S to Alleviate ESBL Escherichia coli-Induced Inflammation in Bovine Mammary Epithelial Cells and Macrophages.
Frontiers in microbiology
Zhuang C,Liu G,Barkema HW,Zhou M,Xu S,Ur Rahman S,Liu Y,Kastelic JP,Gao J,Han B
Mon Sep 28 00:00:00 EDT 2020
Chronic ethanol exposure induces neuroinflammation in H4 cells through TLR3 / NF-κB pathway and anxiety-like behavior in male C57BL/6 mice.
Toxicology
Wang X,Yu H,Wang C,Liu Y,You J,Wang P,Xu G,Shen H,Yao H,Lan X,Zhao R,Wu X,Zhang G
Tue Dec 15 00:00:00 EST 2020
GABA-mediated activated microglia induce neuroinflammation in the hippocampus of mice following cold exposure through the NLRP3 inflammasome and NF-κB signaling pathways.
International immunopharmacology
Lang L,Xu B,Yuan J,Li S,Lian S,Chen Y,Guo J,Yang H
Tue Dec 01 00:00:00 EST 2020
Protective Effects of Cinnamaldehyde against Mesenteric Ischemia-Reperfusion-Induced Lung and Liver Injuries in Rats.
Oxidative medicine and cellular longevity
Almoiliqy M,Wen J,Qaed E,Sun Y,Lian M,Mousa H,Al-Azab M,Zaky MY,Chen D,Wang L,Al-Sharabi A,Liu Z,Sun P,Lin Y
Thu Sep 02 00:00:00 EDT 2021
OAB-14, a bexarotene derivative, improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice.
Biochimica et biophysica acta. Molecular basis of disease
Yuan C,Guo X,Zhou Q,Du F,Jiang W,Zhou X,Liu P,Chi T,Ji X,Gao J,Chen C,Lang H,Xu J,Liu D,Yang Y,Qiu S,Tang X,Chen G,Zou L
Tue Jan 01 00:00:00 EST 2019
OAB-14, a bexarotene derivative, improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice.
Biochimica et biophysica acta. Molecular basis of disease
Yuan C,Guo X,Zhou Q,Du F,Jiang W,Zhou X,Liu P,Chi T,Ji X,Gao J,Chen C,Lang H,Xu J,Liu D,Yang Y,Qiu S,Tang X,Chen G,Zou L
Tue Jan 01 00:00:00 EST 2019
OxLDL induces vascular endothelial cell pyroptosis through miR-125a-5p/TET2 pathway.
Journal of cellular physiology
Zhaolin Z,Jiaojiao C,Peng W,Yami L,Tingting Z,Jun T,Shiyuan W,Jinyan X,Dangheng W,Zhisheng J,Zuo W
Wed May 01 00:00:00 EDT 2019
OxLDL induces vascular endothelial cell pyroptosis through miR-125a-5p/TET2 pathway.
Journal of cellular physiology
Zhaolin Z,Jiaojiao C,Peng W,Yami L,Tingting Z,Jun T,Shiyuan W,Jinyan X,Dangheng W,Zhisheng J,Zuo W
Wed May 01 00:00:00 EDT 2019
Purple sweet potato color attenuated NLRP3 inflammasome by inducing autophagy to delay endothelial senescence.
Journal of cellular physiology
Sun C,Diao Q,Lu J,Zhang Z,Wu D,Wang X,Xie J,Zheng G,Shan Q,Fan S,Hu B,Zheng Y
Wed May 01 00:00:00 EDT 2019
Purple sweet potato color attenuated NLRP3 inflammasome by inducing autophagy to delay endothelial senescence.
Journal of cellular physiology
Sun C,Diao Q,Lu J,Zhang Z,Wu D,Wang X,Xie J,Zheng G,Shan Q,Fan S,Hu B,Zheng Y
Wed May 01 00:00:00 EDT 2019
Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.
International immunopharmacology
He Y,Xia Z,Yu D,Wang J,Jin L,Huang D,Ye X,Li X,Zhang B
Fri Mar 01 00:00:00 EST 2019
Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.
International immunopharmacology
He Y,Xia Z,Yu D,Wang J,Jin L,Huang D,Ye X,Li X,Zhang B
Fri Mar 01 00:00:00 EST 2019
Gasdermin-d Played a Critical Role in the Cyclic Stretch-Induced Inflammatory Reaction in Human Periodontal Ligament Cells.
Inflammation
Zhuang J,Wang Y,Qu F,Wu Y,Zhao D,Xu C
Mon Apr 01 00:00:00 EDT 2019
Gasdermin-d Played a Critical Role in the Cyclic Stretch-Induced Inflammatory Reaction in Human Periodontal Ligament Cells.
Inflammation
Zhuang J,Wang Y,Qu F,Wu Y,Zhao D,Xu C
Mon Apr 01 00:00:00 EDT 2019
Role of Thymoquinone in Cardiac Damage Caused by Sepsis from BALB/c Mice.
Inflammation
Liu H,Sun Y,Zhang Y,Yang G,Guo L,Zhao Y,Pei Z
Mon Apr 01 00:00:00 EDT 2019
Role of Thymoquinone in Cardiac Damage Caused by Sepsis from BALB/c Mice.
Inflammation
Liu H,Sun Y,Zhang Y,Yang G,Guo L,Zhao Y,Pei Z
Mon Apr 01 00:00:00 EDT 2019
Role of Thymoquinone in Cardiac Damage Caused by Sepsis from BALB/c Mice.
Inflammation
Liu H,Sun Y,Zhang Y,Yang G,Guo L,Zhao Y,Pei Z
Mon Apr 01 00:00:00 EDT 2019
Role of Thymoquinone in Cardiac Damage Caused by Sepsis from BALB/c Mice.
Inflammation
Liu H,Sun Y,Zhang Y,Yang G,Guo L,Zhao Y,Pei Z
Mon Apr 01 00:00:00 EDT 2019
The synergistic effect of NOD2 and TLR4 on the activation of autophagy in human submandibular gland inflammation.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Li J,Li B,Cheng Y,Meng Q,Wei L,Li W,Zhang J,Huang S
Tue Jan 01 00:00:00 EST 2019
The synergistic effect of NOD2 and TLR4 on the activation of autophagy in human submandibular gland inflammation.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Li J,Li B,Cheng Y,Meng Q,Wei L,Li W,Zhang J,Huang S
Tue Jan 01 00:00:00 EST 2019
Relationship between serum IL-1β and insomnia and liver depression in patients with perimenopausal non-organic sleep disorder.
Experimental and therapeutic medicine
Li H,Chen Y,Wu H,Huang J,Ma K,Zheng J,Lv S
Tue Jan 01 00:00:00 EST 2019
The Anticonvulsant Effects of Baldrinal on Pilocarpine-Induced convulsion in Adult Male Mice.
Molecules (Basel, Switzerland)
Zhang X,Li X,Liu N,Zheng P,Ma L,Guo F,Sun T,Zhou R,Yu J
Wed Apr 24 00:00:00 EDT 2019
Sweroside Alleviated LPS-Induced Inflammation via SIRT1 Mediating NF-κB and FOXO1 Signaling Pathways in RAW264.7 Cells.
Molecules (Basel, Switzerland)
Wang R,Dong Z,Lan X,Liao Z,Chen M
Fri Mar 01 00:00:00 EST 2019
Sorghum Phenolics Inhibits Inflammasomes in Lipopolysaccharide (LPS)-Primed and Adenosine Triphosphate (ATP)-Activated Macrophages.
Plant foods for human nutrition (Dordrecht, Netherlands)
Dia VP,Bradwell J,Pangloli P
Sun Sep 01 00:00:00 EDT 2019
Ameliorative effects of echinacoside against spinal cord injury via inhibiting NLRP3 inflammasome signaling pathway.
Life sciences
Gao S,Xu T,Guo H,Deng Q,Xun C,Liang W,Sheng W
Fri Nov 15 00:00:00 EST 2019
Upregulation of miR-93 and inhibition of LIMK1 improve ventricular remodeling and alleviate cardiac dysfunction in rats with chronic heart failure by inhibiting RhoA/ROCK signaling pathway activation.
Aging
Su Q,Zhang P,Yu D,Wu Z,Li D,Shen F,Liao P,Yin G
Fri Sep 20 00:00:00 EDT 2019
LXRα promotes cell metastasis by regulating the NLRP3 inflammasome in renal cell carcinoma.
Cell death & disease
Wang K,Xu T,Ruan H,Xiao H,Liu J,Song Z,Cao Q,Bao L,Liu D,Wang C,Cheng G,Liang H,Chen Z,Yang H,Chen K,Zhang X
Fri Feb 15 00:00:00 EST 2019
STING-IRF3 contributes to lipopolysaccharide-induced cardiac dysfunction, inflammation, apoptosis and pyroptosis by activating NLRP3.
Redox biology
Li N,Zhou H,Wu H,Wu Q,Duan M,Deng W,Tang Q
Sat Jun 01 00:00:00 EDT 2019
SETD7 mediates spinal microgliosis and neuropathic pain in a rat model of peripheral nerve injury.
Brain, behavior, and immunity
Shen Y,Ding Z,Ma S,Ding Z,Zhang Y,Zou Y,Xu F,Yang X,Schäfer MKE,Guo Q,Huang C
Fri Nov 01 00:00:00 EDT 2019
LncRNA HIF1A-AS1 contributes to ventricular remodeling after myocardial ischemia/reperfusion injury by adsorption of microRNA-204 to regulating SOCS2 expression.
Cell cycle (Georgetown, Tex.)
Xue X,Luo L
Tue Oct 01 00:00:00 EDT 2019
Purple Sweet Potato Color Attenuates Kidney Damage by Blocking VEGFR2/ROS/NLRP3 Signaling in High-Fat Diet-Treated Mice.
Oxidative medicine and cellular longevity
Zheng GH,Shan Q,Mu JJ,Wang YJ,Zhang ZF,Fan SH,Hu B,Li MQ,Xie J,Chen P,Wu DM,Lu J,Zheng YL
Mon Mar 25 00:00:00 EDT 2019
Juxtaposition of IL-1β and IFN-γ expression and apoptosis of keratinocytes in adult-onset Still's disease.
Expert review of clinical immunology
Rao S,Li Q,Wu H,Zhao M,Wang A,Zhang G,Li J,Lu L,Shi W,Lu Q
Sun Dec 01 00:00:00 EST 2019
Differential immune responses of C57BL/6 mice to infection by Salmonella enterica serovar Typhimurium strain SL1344, CVCC541 and CMCC50115.
Virulence
Wei S,Huang J,Liu Z,Wang M,Zhang B,Lian Z,Guo Y,Han H
Sun Dec 01 00:00:00 EST 2019
Gender Difference in Damage-Mediated Signaling Contributes to Pulmonary Arterial Hypertension.
Antioxidants & redox signaling
Rafikov R,Nair V,Sinari S,Babu H,Sullivan JC,Yuan JX,Desai AA,Rafikova O
Fri Nov 01 00:00:00 EDT 2019
Iguratimod (T-614) attenuates severe acute pancreatitis by inhibiting the NLRP3 inflammasome and NF-κB pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Hou C,Zhu X,Shi C,Peng Y,Huang D,Li Q,Miao Y
Fri Nov 01 00:00:00 EDT 2019
IMM-H007, a novel small molecule inhibitor for atherosclerosis, represses endothelium inflammation by regulating the activity of NF-κB and JNK/AP1 signaling.
Toxicology and applied pharmacology
Yu J,Ming H,Li HY,Yu B,Chu M,Zhu H,Zhu X
Tue Oct 15 00:00:00 EDT 2019
TAK242 suppresses the TLR4 signaling pathway and ameliorates DCD liver IRI in rats.
Molecular medicine reports
Zhong X,Xiao Q,Liu Z,Wang W,Lai CH,Yang W,Yue P,Ye Q,Xiao J
Sun Sep 01 00:00:00 EDT 2019
Clock mutant promotes osteoarthritis by inhibiting the acetylation of NFκB.
Osteoarthritis and cartilage
Yuan G,Xu L,Cai T,Hua B,Sun N,Yan Z,Lu C,Qian R
Sat Jun 01 00:00:00 EDT 2019
An NLRP3 inflammasome-triggered cytokine storm contributes to Streptococcal toxic shock-like syndrome (STSLS).
PLoS pathogens
Lin L,Xu L,Lv W,Han L,Xiang Y,Fu L,Jin M,Zhou R,Chen H,Zhang A
Sat Jun 01 00:00:00 EDT 2019
Pioglitazone decreased renal calcium oxalate crystal formation by suppressing M1 macrophage polarization via the PPAR-γ-miR-23 axis.
American journal of physiology. Renal physiology
Chen Z,Yuan P,Sun X,Tang K,Liu H,Han S,Ye T,Liu X,Yang X,Zeng J,Yan L,Xing J,Xiao K,Ye Z,Xu H
Mon Jul 01 00:00:00 EDT 2019
Helicobacter pylori-induced YAP1 nuclear translocation promotes gastric carcinogenesis by enhancing IL-1β expression.
Cancer medicine
Wu Y,Shen L,Liang X,Li S,Ma L,Zheng L,Li T,Yu H,Chan H,Chen C,Yu J,Jia J
Mon Jul 01 00:00:00 EDT 2019
Caspase-11 promotes renal fibrosis by stimulating IL-1β maturation via activating caspase-1.
Acta pharmacologica Sinica
Miao NJ,Xie HY,Xu D,Yin JY,Wang YZ,Wang B,Yin F,Zhou ZL,Cheng Q,Chen PP,Zhou L,Xue H,Zhang W,Wang XX,Liu J,Lu LM
Sat Jun 01 00:00:00 EDT 2019
Migratory Neural Crest Cells Phagocytose Dead Cells in the Developing Nervous System.
Cell
Zhu Y,Crowley SC,Latimer AJ,Lewis GM,Nash R,Kucenas S
Thu Sep 19 00:00:00 EDT 2019
Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs.
Journal of agricultural and food chemistry
Jia YN,Peng YL,Zhao YP,Cheng XF,Zhou Y,Chai CL,Zeng LS,Pan MH,Xu L
Wed May 15 00:00:00 EDT 2019
Hydrogen Inhalation Attenuates Oxidative Stress Related Endothelial Cells Injury After Subarachnoid Hemorrhage in Rats.
Frontiers in neuroscience
Zhuang K,Zuo YC,Sherchan P,Wang JK,Yan XX,Liu F
Mon Sep 28 00:00:00 EDT 2020
NLRP3 inflammasome plays an important role in caspase-1 activation and IL-1β secretion in macrophages infected with Pasteurella multocida.
Veterinary microbiology
Fang R,Du H,Lei G,Liu Y,Feng S,Ye C,Li N,Peng Y
Mon Apr 01 00:00:00 EDT 2019
Liraglutide ameliorates non-alcoholic steatohepatitis by inhibiting NLRP3 inflammasome and pyroptosis activation via mitophagy.
European journal of pharmacology
Yu X,Hao M,Liu Y,Ma X,Lin W,Xu Q,Zhou H,Shao N,Kuang H
Sun Dec 01 00:00:00 EST 2019
Akt inhibitor deguelin aggravates inflammation and fibrosis in myocarditis.
Iranian journal of basic medical sciences
Li S,Wang Y,Zhao C,Zhang M,Wang W,Yu X,Huang J,Wang Z,Zhu B,Yin C,Cai H
Fri Nov 01 00:00:00 EDT 2019
Akt inhibitor deguelin aggravates inflammation and fibrosis in myocarditis.
Iranian journal of basic medical sciences
Li S,Wang Y,Zhao C,Zhang M,Wang W,Yu X,Huang J,Wang Z,Zhu B,Yin C,Cai H
Fri Nov 01 00:00:00 EDT 2019
Rice Protein Exerts Anti-Inflammatory Effect in Growing and Adult Rats via Suppressing NF-κB Pathway.
International journal of molecular sciences
Wang Z,Liang M,Li H,Cai L,Yang L
Fri Dec 06 00:00:00 EST 2019
p66Shc Contributes to Liver Fibrosis through the Regulation of Mitochondrial Reactive Oxygen Species.
Theranostics
Zhao Y,Wang Z,Feng D,Zhao H,Lin M,Hu Y,Zhang N,Lv L,Gao Z,Zhai X,Tian X,Yao J
Fri Jan 31 00:00:00 EST 2020
Curcumin attenuates potassium oxonate-induced hyperuricemia and kidney inflammation in mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Chen Y,Li C,Duan S,Yuan X,Liang J,Hou S
Tue Oct 01 00:00:00 EDT 2019
Curcumin attenuates potassium oxonate-induced hyperuricemia and kidney inflammation in mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Chen Y,Li C,Duan S,Yuan X,Liang J,Hou S
Tue Oct 01 00:00:00 EDT 2019
MiR-143-3p directly targets GLUT9 to reduce uric acid reabsorption and inflammatory response of renal tubular epithelial cells.
Biochemical and biophysical research communications
Zhou Z,Dong Y,Zhou H,Liu J,Zhao W
Tue Sep 24 00:00:00 EDT 2019
Chitosan Hydrogel Delivery System Containing Herbal Compound Functions as a Potential Antineuroinflammatory Agent.
ACS omega
Zhou J,Zheng J,Zhang Y,Zheng P,Tang T,Luo JK,Cui HJ,Song RR,Wang Y
Sun Jun 30 00:00:00 EDT 2019
Chitosan Hydrogel Delivery System Containing Herbal Compound Functions as a Potential Antineuroinflammatory Agent.
ACS omega
Zhou J,Zheng J,Zhang Y,Zheng P,Tang T,Luo JK,Cui HJ,Song RR,Wang Y
Sun Jun 30 00:00:00 EDT 2019
Pyroptosis engagement and bladder urothelial cell-derived exosomes recruit mast cells and induce barrier dysfunction of bladder urothelium after uropathogenic E. coli infection.
American journal of physiology. Cell physiology
Wu Z,Li Y,Liu Q,Liu Y,Chen L,Zhao H,Guo H,Zhu K,Zhou N,Chai TC,Shi B
Sun Sep 01 00:00:00 EDT 2019
Protective effects of ginsenoside Rk3 against chronic alcohol-induced liver injury in mice through inhibition of inflammation, oxidative stress, and apoptosis.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Qu L,Zhu Y,Liu Y,Yang H,Zhu C,Ma P,Deng J,Fan D
Mon Apr 01 00:00:00 EDT 2019
Antitumor Effects of Berberine on Gliomas via Inactivation of Caspase-1-Mediated IL-1β and IL-18 Release.
Frontiers in oncology
Tong L,Xie C,Wei Y,Qu Y,Liang H,Zhang Y,Xu T,Qian X,Qiu H,Deng H
Thu Oct 01 00:00:00 EDT 2020
Berberine inhibits NLRP3 Inflammasome pathway in human triple-negative breast cancer MDA-MB-231 cell.
BMC complementary and alternative medicine
Yao M,Fan X,Yuan B,Takagi N,Liu S,Han X,Ren J,Liu J
Wed Aug 14 00:00:00 EDT 2019
Directed self-assembly of herbal small molecules into sustained release hydrogels for treating neural inflammation.
Nature communications
Zheng J,Fan R,Wu H,Yao H,Yan Y,Liu J,Ran L,Sun Z,Yi L,Dang L,Gan P,Zheng P,Yang T,Zhang Y,Tang T,Wang Y
Mon Apr 08 00:00:00 EDT 2019
Directed self-assembly of herbal small molecules into sustained release hydrogels for treating neural inflammation.
Nature communications
Zheng J,Fan R,Wu H,Yao H,Yan Y,Liu J,Ran L,Sun Z,Yi L,Dang L,Gan P,Zheng P,Yang T,Zhang Y,Tang T,Wang Y
Mon Apr 08 00:00:00 EDT 2019
Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure.
Biomolecules
Xu B,Lang LM,Li SZ,Guo JR,Wang JF,Yang HM,Lian S
Fri Aug 30 00:00:00 EDT 2019
Vaccaria n-Butanol Extract Lower the Production of Proinflammatory Cytokines and the Infection Risk of T. spiralis In Vivo.
Acta parasitologica
Xu F,Hou B,Zhu X,Liu Y,Shi X,Li S,Li Z,Cai W,Zhou Y,Qiu L
Sun Sep 01 00:00:00 EDT 2019
Schwann cell transplantation exerts neuroprotective roles in rat model of spinal cord injury by combating inflammasome activation and improving motor recovery and remyelination.
Metabolic brain disease
Mousavi M,Hedayatpour A,Mortezaee K,Mohamadi Y,Abolhassani F,Hassanzadeh G
Thu Aug 01 00:00:00 EDT 2019
NLRP3 inflammasome activates interleukin-23/interleukin-17 axis during ischaemia-reperfusion injury in cerebral ischaemia in mice.
Life sciences
Wang H,Zhong D,Chen H,Jin J,Liu Q,Li G
Sat Jun 15 00:00:00 EDT 2019
Tougu Xiaotong capsule exerts a therapeutic effect on knee osteoarthritis by regulating subchondral bone remodeling.
Molecular medicine reports
Wu G,Zhang J,Chen W,Chen S,Huang Y,Lin R,Huang M,Li Z,Zheng L,Li X
Fri Mar 01 00:00:00 EST 2019
NLRP3 Inflammasome Is Involved in Calcium-Sensing Receptor-Induced Aortic Remodeling in SHRs.
Mediators of inflammation
Zhang X,Hong S,Qi S,Liu W,Zhang X,Shi Z,Chen W,Zhao M,Yin X
Mon Jul 22 00:00:00 EDT 2019
Hydrogen inhalation protects hypoxic-ischemic brain damage by attenuating inflammation and apoptosis in neonatal rats.
Experimental biology and medicine (Maywood, N.J.)
Wu G,Chen Z,Wang P,Zhao M,Fujino M,Zhang C,Zhou W,Hirano SI,Li XK,Zhao L
Sun Sep 01 00:00:00 EDT 2019
Bacteroides fragilis Strain ZY-312 Defense against Cronobacter sakazakii-Induced Necrotizing Enterocolitis In Vitro and in a Neonatal Rat Model.
mSystems
Fan H,Chen Z,Lin R,Liu Y,Wu X,Puthiyakunnon S,Wang Y,Zhu B,Zhang Q,Bai Y,Zhi F
Tue Aug 06 00:00:00 EDT 2019
Omentin-1 prevents inflammation-induced osteoporosis by downregulating the pro-inflammatory cytokines.
Bone research
Rao SS,Hu Y,Xie PL,Cao J,Wang ZX,Liu JH,Yin H,Huang J,Tan YJ,Luo J,Luo MJ,Tang SY,Chen TH,Yuan LQ,Liao EY,Xu R,Liu ZZ,Chen CY,Xie H
Sun Nov 12 00:00:00 EST 2023
Omentin-1 prevents inflammation-induced osteoporosis by downregulating the pro-inflammatory cytokines.
Bone research
Rao SS,Hu Y,Xie PL,Cao J,Wang ZX,Liu JH,Yin H,Huang J,Tan YJ,Luo J,Luo MJ,Tang SY,Chen TH,Yuan LQ,Liao EY,Xu R,Liu ZZ,Chen CY,Xie H
Sun Nov 12 00:00:00 EST 2023
Omentin-1 prevents inflammation-induced osteoporosis by downregulating the pro-inflammatory cytokines.
Bone research
Rao SS,Hu Y,Xie PL,Cao J,Wang ZX,Liu JH,Yin H,Huang J,Tan YJ,Luo J,Luo MJ,Tang SY,Chen TH,Yuan LQ,Liao EY,Xu R,Liu ZZ,Chen CY,Xie H
Sun Nov 12 00:00:00 EST 2023
Omentin-1 prevents inflammation-induced osteoporosis by downregulating the pro-inflammatory cytokines.
Bone research
Rao SS,Hu Y,Xie PL,Cao J,Wang ZX,Liu JH,Yin H,Huang J,Tan YJ,Luo J,Luo MJ,Tang SY,Chen TH,Yuan LQ,Liao EY,Xu R,Liu ZZ,Chen CY,Xie H
Sun Nov 12 00:00:00 EST 2023
Tumor-Stroma IL1β-IRAK4 Feedforward Circuitry Drives Tumor Fibrosis, Chemoresistance, and Poor Prognosis in Pancreatic Cancer.
Cancer research
Zhang D,Li L,Jiang H,Li Q,Wang-Gillam A,Yu J,Head R,Liu J,Ruzinova MB,Lim KH
Sun Apr 01 00:00:00 EDT 2018
Tumor-Stroma IL1β-IRAK4 Feedforward Circuitry Drives Tumor Fibrosis, Chemoresistance, and Poor Prognosis in Pancreatic Cancer.
Cancer research
Zhang D,Li L,Jiang H,Li Q,Wang-Gillam A,Yu J,Head R,Liu J,Ruzinova MB,Lim KH
Sun Apr 01 00:00:00 EDT 2018
CAPE-pNO2 attenuates diabetic cardiomyopathy through the NOX4/NF-κB pathway in STZ-induced diabetic mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Fan L,Xiao Q,Zhang L,Wang X,Huang Q,Li S,Zhao X,Li Z
Sat Dec 01 00:00:00 EST 2018
CAPE-pNO2 attenuates diabetic cardiomyopathy through the NOX4/NF-κB pathway in STZ-induced diabetic mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Fan L,Xiao Q,Zhang L,Wang X,Huang Q,Li S,Zhao X,Li Z
Sat Dec 01 00:00:00 EST 2018
Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Lu X,Liu T,Chen K,Xia Y,Dai W,Xu S,Xu L,Wang F,Wu L,Li J,Li S,Wang W,Yu Q,Feng J,Fan X,Zhou Y,Niu P,Guo C
Sun Jul 01 00:00:00 EDT 2018
Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Lu X,Liu T,Chen K,Xia Y,Dai W,Xu S,Xu L,Wang F,Wu L,Li J,Li S,Wang W,Yu Q,Feng J,Fan X,Zhou Y,Niu P,Guo C
Sun Jul 01 00:00:00 EDT 2018
Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Lu X,Liu T,Chen K,Xia Y,Dai W,Xu S,Xu L,Wang F,Wu L,Li J,Li S,Wang W,Yu Q,Feng J,Fan X,Zhou Y,Niu P,Guo C
Sun Jul 01 00:00:00 EDT 2018
Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Lu X,Liu T,Chen K,Xia Y,Dai W,Xu S,Xu L,Wang F,Wu L,Li J,Li S,Wang W,Yu Q,Feng J,Fan X,Zhou Y,Niu P,Guo C
Sun Jul 01 00:00:00 EDT 2018
Methane-Rich Saline Ameliorates Sepsis-Induced Acute Kidney Injury through Anti-Inflammation, Antioxidative, and Antiapoptosis Effects by Regulating Endoplasmic Reticulum Stress.
Oxidative medicine and cellular longevity
Jia Y,Li Z,Feng Y,Cui R,Dong Y,Zhang X,Xiang X,Qu K,Liu C,Zhang J
Tue Jan 22 00:00:00 EST 2019
Methane-Rich Saline Ameliorates Sepsis-Induced Acute Kidney Injury through Anti-Inflammation, Antioxidative, and Antiapoptosis Effects by Regulating Endoplasmic Reticulum Stress.
Oxidative medicine and cellular longevity
Jia Y,Li Z,Feng Y,Cui R,Dong Y,Zhang X,Xiang X,Qu K,Liu C,Zhang J
Tue Jan 22 00:00:00 EST 2019
Casticin prevents DSS induced ulcerative colitis in mice through inhibitions of NF-κB pathway and ROS signaling.
Phytotherapy research : PTR
Ma J,Yin G,Lu Z,Xie P,Zhou H,Liu J,Yu L
Sat Sep 01 00:00:00 EDT 2018
Casticin prevents DSS induced ulcerative colitis in mice through inhibitions of NF-κB pathway and ROS signaling.
Phytotherapy research : PTR
Ma J,Yin G,Lu Z,Xie P,Zhou H,Liu J,Yu L
Sat Sep 01 00:00:00 EDT 2018
Casticin prevents DSS induced ulcerative colitis in mice through inhibitions of NF-κB pathway and ROS signaling.
Phytotherapy research : PTR
Ma J,Yin G,Lu Z,Xie P,Zhou H,Liu J,Yu L
Sat Sep 01 00:00:00 EDT 2018
Casticin prevents DSS induced ulcerative colitis in mice through inhibitions of NF-κB pathway and ROS signaling.
Phytotherapy research : PTR
Ma J,Yin G,Lu Z,Xie P,Zhou H,Liu J,Yu L
Sat Sep 01 00:00:00 EDT 2018
Lysyl oxidase blockade ameliorates anovulation in polycystic ovary syndrome.
Human reproduction (Oxford, England)
Zhang C,Ma J,Wang W,Sun Y,Sun K
Thu Nov 01 00:00:00 EDT 2018
Lysyl oxidase blockade ameliorates anovulation in polycystic ovary syndrome.
Human reproduction (Oxford, England)
Zhang C,Ma J,Wang W,Sun Y,Sun K
Thu Nov 01 00:00:00 EDT 2018
Expression and clinical significance of the NEK7-NLRP3 inflammasome signaling pathway in patients with systemic lupus erythematosus.
Journal of inflammation (London, England)
Ma ZZ,Sun HS,Lv JC,Guo L,Yang QR
Mon Mar 21 00:00:00 EDT 2022
Expression and clinical significance of the NEK7-NLRP3 inflammasome signaling pathway in patients with systemic lupus erythematosus.
Journal of inflammation (London, England)
Ma ZZ,Sun HS,Lv JC,Guo L,Yang QR
Mon Mar 21 00:00:00 EDT 2022
Combination Treatment of Icariin and L-DOPA Against 6-OHDA-Lesioned Dopamine Neurotoxicity.
Frontiers in molecular neuroscience
Lu DS,Chen C,Zheng YX,Li DD,Wang GQ,Liu J,Shi J,Zhang F
Thu Oct 01 00:00:00 EDT 2020
Combination Treatment of Icariin and L-DOPA Against 6-OHDA-Lesioned Dopamine Neurotoxicity.
Frontiers in molecular neuroscience
Lu DS,Chen C,Zheng YX,Li DD,Wang GQ,Liu J,Shi J,Zhang F
Thu Oct 01 00:00:00 EDT 2020
Inhibition of Heat Shock Protein 90 by 17-AAG Reduces Inflammation via P2X7 Receptor/NLRP3 Inflammasome Pathway and Increases Neurogenesis After Subarachnoid Hemorrhage in Mice.
Frontiers in molecular neuroscience
Zuo Y,Wang J,Liao F,Yan X,Li J,Huang L,Liu F
Thu Oct 01 00:00:00 EDT 2020
Inhibition of Heat Shock Protein 90 by 17-AAG Reduces Inflammation via P2X7 Receptor/NLRP3 Inflammasome Pathway and Increases Neurogenesis After Subarachnoid Hemorrhage in Mice.
Frontiers in molecular neuroscience
Zuo Y,Wang J,Liao F,Yan X,Li J,Huang L,Liu F
Thu Oct 01 00:00:00 EDT 2020
Effects of Dandelion Extract on the Proliferation of Rat Skeletal Muscle Cells and the Inhibition of a Lipopolysaccharide-Induced Inflammatory Reaction.
Chinese medical journal
Liu Q,Zhao H,Gao Y,Meng Y,Zhao XX,Pan SN
Fri Jul 20 00:00:00 EDT 2018
Effects of Dandelion Extract on the Proliferation of Rat Skeletal Muscle Cells and the Inhibition of a Lipopolysaccharide-Induced Inflammatory Reaction.
Chinese medical journal
Liu Q,Zhao H,Gao Y,Meng Y,Zhao XX,Pan SN
Fri Jul 20 00:00:00 EDT 2018
Nicotine-Induced Neuroprotection against Cognitive Dysfunction after Partial Hepatectomy Involves Activation of BDNF/TrkB Signaling Pathway and Inhibition of NF-κB Signaling Pathway in Aged Rats.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Wei P,Zheng Q,Liu H,Wan T,Zhou J,Li D,Zhou H,Li J,Ji F,Tang W,Li J
Tue Mar 06 00:00:00 EST 2018
Nicotine-Induced Neuroprotection against Cognitive Dysfunction after Partial Hepatectomy Involves Activation of BDNF/TrkB Signaling Pathway and Inhibition of NF-κB Signaling Pathway in Aged Rats.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Wei P,Zheng Q,Liu H,Wan T,Zhou J,Li D,Zhou H,Li J,Ji F,Tang W,Li J
Tue Mar 06 00:00:00 EST 2018
Hydrogen sulfide protects neonatal rat medulla oblongata against prenatal cigarette smoke exposure via anti-oxidative and anti-inflammatory effects.
Environmental toxicology and pharmacology
Yan X,Lei F,Hu Y,Nie L,Jia Q,Zhou H,Zhao F,Zheng Y
Mon Jan 01 00:00:00 EST 2018
Hydrogen sulfide protects neonatal rat medulla oblongata against prenatal cigarette smoke exposure via anti-oxidative and anti-inflammatory effects.
Environmental toxicology and pharmacology
Yan X,Lei F,Hu Y,Nie L,Jia Q,Zhou H,Zhao F,Zheng Y
Mon Jan 01 00:00:00 EST 2018
The role of the microRNA-146a/complement factor H/interleukin-1β-mediated inflammatory loop circuit in the perpetuate inflammation of chronic temporal lobe epilepsy.
Disease models & mechanisms
Li TR,Jia YJ,Ma C,Qiu WY,Wang Q,Shao XQ,Lv RJ
Fri Mar 23 00:00:00 EDT 2018
The role of the microRNA-146a/complement factor H/interleukin-1β-mediated inflammatory loop circuit in the perpetuate inflammation of chronic temporal lobe epilepsy.
Disease models & mechanisms
Li TR,Jia YJ,Ma C,Qiu WY,Wang Q,Shao XQ,Lv RJ
Fri Mar 23 00:00:00 EDT 2018
Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.
International immunopharmacology
Jia YN,Lu HP,Peng YL,Zhang BS,Gong XB,Su J,Zhou Y,Pan MH,Xu L
Thu Mar 01 00:00:00 EST 2018
Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.
International immunopharmacology
Jia YN,Lu HP,Peng YL,Zhang BS,Gong XB,Su J,Zhou Y,Pan MH,Xu L
Thu Mar 01 00:00:00 EST 2018
Telbivudine attenuates UUO-induced renal fibrosis via TGF-β/Smad and NF-κB signaling.
International immunopharmacology
Chen J,Li D
Thu Feb 01 00:00:00 EST 2018
Telbivudine attenuates UUO-induced renal fibrosis via TGF-β/Smad and NF-κB signaling.
International immunopharmacology
Chen J,Li D
Thu Feb 01 00:00:00 EST 2018
Naringin Dihydrochalcone Ameliorates Cognitive Deficits and Neuropathology in APP/PS1 Transgenic Mice.
Frontiers in aging neuroscience
Yang W,Zhou K,Zhou Y,An Y,Hu T,Lu J,Huang S,Pei G
Wed Sep 30 00:00:00 EDT 2020
Naringin Dihydrochalcone Ameliorates Cognitive Deficits and Neuropathology in APP/PS1 Transgenic Mice.
Frontiers in aging neuroscience
Yang W,Zhou K,Zhou Y,An Y,Hu T,Lu J,Huang S,Pei G
Wed Sep 30 00:00:00 EDT 2020
Curcumin Attenuates Colistin-Induced Neurotoxicity in N2a Cells via Anti-inflammatory Activity, Suppression of Oxidative Stress, and Apoptosis.
Molecular neurobiology
Dai C,Ciccotosto GD,Cappai R,Tang S,Li D,Xie S,Xiao X,Velkov T
Mon Jan 01 00:00:00 EST 2018
Curcumin Attenuates Colistin-Induced Neurotoxicity in N2a Cells via Anti-inflammatory Activity, Suppression of Oxidative Stress, and Apoptosis.
Molecular neurobiology
Dai C,Ciccotosto GD,Cappai R,Tang S,Li D,Xie S,Xiao X,Velkov T
Mon Jan 01 00:00:00 EST 2018
Autocrine IL-1β mediates the promotion of corneal neovascularization by senescent fibroblasts.
American journal of physiology. Cell physiology
Dong M,Yang L,Qu M,Hu X,Duan H,Zhang X,Shi W,Zhou Q
Thu Nov 01 00:00:00 EDT 2018
Autocrine IL-1β mediates the promotion of corneal neovascularization by senescent fibroblasts.
American journal of physiology. Cell physiology
Dong M,Yang L,Qu M,Hu X,Duan H,Zhang X,Shi W,Zhou Q
Thu Nov 01 00:00:00 EDT 2018
Protective effects of mitochondrion-targeted peptide SS-31 against hind limb ischemia-reperfusion injury.
Journal of physiology and biochemistry
Cai J,Jiang Y,Zhang M,Zhao H,Li H,Li K,Zhang X,Qiao T
Tue May 01 00:00:00 EDT 2018
Protective effects of mitochondrion-targeted peptide SS-31 against hind limb ischemia-reperfusion injury.
Journal of physiology and biochemistry
Cai J,Jiang Y,Zhang M,Zhao H,Li H,Li K,Zhang X,Qiao T
Tue May 01 00:00:00 EDT 2018
Fenofibrate Exerts Protective Effects in Diabetic Retinopathy via Inhibition of the ANGPTL3 Pathway.
Investigative ophthalmology & visual science
Wang N,Zou C,Zhao S,Wang Y,Han C,Zheng Z
Wed Aug 01 00:00:00 EDT 2018
Fungal β-Glucan Activates the NLRP3 Inflammasome in Human Bronchial Epithelial Cells Through ROS Production.
Inflammation
Huang Y,Hua M,Cui X
Thu Feb 01 00:00:00 EST 2018
Fungal β-Glucan Activates the NLRP3 Inflammasome in Human Bronchial Epithelial Cells Through ROS Production.
Inflammation
Huang Y,Hua M,Cui X
Thu Feb 01 00:00:00 EST 2018
(2R,3R)Dihydromyricetin inhibits osteoclastogenesis and bone loss through scavenging LPS-induced oxidative stress and NF-κB and MAPKs pathways activating.
Journal of cellular biochemistry
Zhang X,Li X,Fang J,Hou X,Fang H,Guo F,Li F,Chen A,Huang S
Thu Nov 01 00:00:00 EDT 2018
(2R,3R)Dihydromyricetin inhibits osteoclastogenesis and bone loss through scavenging LPS-induced oxidative stress and NF-κB and MAPKs pathways activating.
Journal of cellular biochemistry
Zhang X,Li X,Fang J,Hou X,Fang H,Guo F,Li F,Chen A,Huang S
Thu Nov 01 00:00:00 EDT 2018
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Neurochemistry international
Zhang J,Tucker LD,Lu Y,Yang L,Wu C,Li Y,Zhang Q
Fri Jun 01 00:00:00 EDT 2018
Mini-peptide RPL41 attenuated retinal neovascularization by inducing degradation of ATF4 in oxygen-induced retinopathy mice.
Experimental cell research
Geng W,Qin F,Ren J,Xiao S,Wang A
Wed Aug 15 00:00:00 EDT 2018
Mini-peptide RPL41 attenuated retinal neovascularization by inducing degradation of ATF4 in oxygen-induced retinopathy mice.
Experimental cell research
Geng W,Qin F,Ren J,Xiao S,Wang A
Wed Aug 15 00:00:00 EDT 2018
NADH protect against radiation enteritis by enhancing autophagy and inhibiting inflammation through PI3K/AKT pathway.
American journal of translational research
Wang JT,Xie WQ,Liu FQ,Bi Y,Zhu XJ,Wang QE,Zheng YF
Thu Oct 01 00:00:00 EDT 2020
NADH protect against radiation enteritis by enhancing autophagy and inhibiting inflammation through PI3K/AKT pathway.
American journal of translational research
Wang JT,Xie WQ,Liu FQ,Bi Y,Zhu XJ,Wang QE,Zheng YF
Thu Oct 01 00:00:00 EDT 2020
Proteomic profiling of human decidual immune proteins during Toxoplasma gondii infection.
Journal of proteomics
Zhang D,Sun X,Ren L,Yang C,Liu X,Zhang H,Jiang Y,Hu X
Thu Aug 30 00:00:00 EDT 2018
Proteomic profiling of human decidual immune proteins during Toxoplasma gondii infection.
Journal of proteomics
Zhang D,Sun X,Ren L,Yang C,Liu X,Zhang H,Jiang Y,Hu X
Thu Aug 30 00:00:00 EDT 2018
Mechanism of salvianolic acid B neuroprotection against ischemia/reperfusion induced cerebral injury.
Brain research
Fan Y,Luo Q,Wei J,Lin R,Lin L,Li Y,Chen Z,Lin W,Chen Q
Mon Jan 15 00:00:00 EST 2018
Mechanism of salvianolic acid B neuroprotection against ischemia/reperfusion induced cerebral injury.
Brain research
Fan Y,Luo Q,Wei J,Lin R,Lin L,Li Y,Chen Z,Lin W,Chen Q
Mon Jan 15 00:00:00 EST 2018
NF-E2-Related Factor 2 Suppresses Intestinal Fibrosis by Inhibiting Reactive Oxygen Species-Dependent TGF-β1/SMADs Pathway.
Digestive diseases and sciences
Guan Y,Tan Y,Liu W,Yang J,Wang D,Pan D,Sun Y,Zheng C
Thu Feb 01 00:00:00 EST 2018
NF-E2-Related Factor 2 Suppresses Intestinal Fibrosis by Inhibiting Reactive Oxygen Species-Dependent TGF-β1/SMADs Pathway.
Digestive diseases and sciences
Guan Y,Tan Y,Liu W,Yang J,Wang D,Pan D,Sun Y,Zheng C
Thu Feb 01 00:00:00 EST 2018
Prenatal cold stress: Effect on maternal hippocampus and offspring behavior in rats.
Behavioural brain research
Lian S,Wang D,Xu B,Guo W,Wang L,Li W,Ji H,Wang J,Kong F,Zhen L,Li S,Zhang L,Guo J,Yang H
Mon Jul 02 00:00:00 EDT 2018
Prenatal cold stress: Effect on maternal hippocampus and offspring behavior in rats.
Behavioural brain research
Lian S,Wang D,Xu B,Guo W,Wang L,Li W,Ji H,Wang J,Kong F,Zhen L,Li S,Zhang L,Guo J,Yang H
Mon Jul 02 00:00:00 EDT 2018
Role of Brain-Derived Neurotrophic Factor in Endometriosis Pain.
Reproductive sciences (Thousand Oaks, Calif.)
Ding S,Zhu T,Tian Y,Xu P,Chen Z,Huang X,Zhang X
Sun Jul 01 00:00:00 EDT 2018
Role of Brain-Derived Neurotrophic Factor in Endometriosis Pain.
Reproductive sciences (Thousand Oaks, Calif.)
Ding S,Zhu T,Tian Y,Xu P,Chen Z,Huang X,Zhang X
Sun Jul 01 00:00:00 EDT 2018
Influence of vitamin D deficiency on T cell subsets and related indices during spinal tuberculosis.
Experimental and therapeutic medicine
Zhou SH,Wang X,Fan MY,Li HL,Bian F,Huang T,Fang HY
Wed Aug 01 00:00:00 EDT 2018
Influence of vitamin D deficiency on T cell subsets and related indices during spinal tuberculosis.
Experimental and therapeutic medicine
Zhou SH,Wang X,Fan MY,Li HL,Bian F,Huang T,Fang HY
Wed Aug 01 00:00:00 EDT 2018
Establishment of experimental autoimmune prostatitis model by T2 peptide in aluminium hydroxide adjuvant.
Andrologia
Zhang L,Ihsan AU,Cao Y,Cheng Y,Zhou X
Sun Apr 01 00:00:00 EDT 2018
Establishment of experimental autoimmune prostatitis model by T2 peptide in aluminium hydroxide adjuvant.
Andrologia
Zhang L,Ihsan AU,Cao Y,Cheng Y,Zhou X
Sun Apr 01 00:00:00 EDT 2018
Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells.
Nature communications
Takahashi A,Loo TM,Okada R,Kamachi F,Watanabe Y,Wakita M,Watanabe S,Kawamoto S,Miyata K,Barber GN,Ohtani N,Hara E
Wed Mar 28 00:00:00 EDT 2018
Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells.
Nature communications
Takahashi A,Loo TM,Okada R,Kamachi F,Watanabe Y,Wakita M,Watanabe S,Kawamoto S,Miyata K,Barber GN,Ohtani N,Hara E
Wed Mar 28 00:00:00 EDT 2018
Pyroptosis induced by enterovirus 71 and coxsackievirus B3 infection affects viral replication and host response.
Scientific reports
Wang Y,Qin Y,Wang T,Chen Y,Lang X,Zheng J,Gao S,Chen S,Zhong X,Mu Y,Wu X,Zhang F,Zhao W,Zhong Z
Tue Feb 13 00:00:00 EST 2018
Pyroptosis induced by enterovirus 71 and coxsackievirus B3 infection affects viral replication and host response.
Scientific reports
Wang Y,Qin Y,Wang T,Chen Y,Lang X,Zheng J,Gao S,Chen S,Zhong X,Mu Y,Wu X,Zhang F,Zhao W,Zhong Z
Tue Feb 13 00:00:00 EST 2018
Vaccarin alleviates hypertension and nephropathy in renovascular hypertensive rats.
Experimental and therapeutic medicine
Cai W,Zhang Z,Huang Y,Sun H,Qiu L
Mon Jan 01 00:00:00 EST 2018
Effects of platelet-rich plasma on the activity of human menstrual blood-derived stromal cells in vitro.
Stem cell research & therapy
Zhang S,Li P,Yuan Z,Tan J
Mon Feb 26 00:00:00 EST 2018
Effects of platelet-rich plasma on the activity of human menstrual blood-derived stromal cells in vitro.
Stem cell research & therapy
Zhang S,Li P,Yuan Z,Tan J
Mon Feb 26 00:00:00 EST 2018
Tumour YAP1 and PTEN expression correlates with tumour-associated myeloid suppressor cell expansion and reduced survival in colorectal cancer.
Immunology
Yang R,Cai TT,Wu XJ,Liu YN,He J,Zhang XS,Ma G,Li J
Mon Oct 01 00:00:00 EDT 2018
Carbon monoxide-releasing molecule-3 protects against ischemic stroke by suppressing neuroinflammation and alleviating blood-brain barrier disruption.
Journal of neuroinflammation
Wang J,Zhang D,Fu X,Yu L,Lu Z,Gao Y,Liu X,Man J,Li S,Li N,Chen X,Hong M,Yang Q,Wang J
Thu Jun 21 00:00:00 EDT 2018
Carbon monoxide-releasing molecule-3 protects against ischemic stroke by suppressing neuroinflammation and alleviating blood-brain barrier disruption.
Journal of neuroinflammation
Wang J,Zhang D,Fu X,Yu L,Lu Z,Gao Y,Liu X,Man J,Li S,Li N,Chen X,Hong M,Yang Q,Wang J
Thu Jun 21 00:00:00 EDT 2018
Protective Effects of Costunolide Against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice.
Frontiers in pharmacology
Mao J,Yi M,Wang R,Huang Y,Chen M
Sat Apr 09 00:00:00 EDT 2022
Protective Effects of Costunolide Against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice.
Frontiers in pharmacology
Mao J,Yi M,Wang R,Huang Y,Chen M
Sat Apr 09 00:00:00 EDT 2022
Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages in zebrafish spinal cord regeneration.
Nature communications
Tsarouchas TM,Wehner D,Cavone L,Munir T,Keatinge M,Lambertus M,Underhill A,Barrett T,Kassapis E,Ogryzko N,Feng Y,van Ham TJ,Becker T,Becker CG
Wed Nov 07 00:00:00 EST 2018
Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages in zebrafish spinal cord regeneration.
Nature communications
Tsarouchas TM,Wehner D,Cavone L,Munir T,Keatinge M,Lambertus M,Underhill A,Barrett T,Kassapis E,Ogryzko N,Feng Y,van Ham TJ,Becker T,Becker CG
Wed Nov 07 00:00:00 EST 2018
Surgical incision induces learning impairment in mice partially through inhibition of the brain-derived neurotrophic factor signaling pathway in the hippocampus and amygdala.
Molecular pain
Liu Z,Liu F,Liu X,Ma C,Zhao J
Mon Jan 14 00:00:00 EST 2019
Surgical incision induces learning impairment in mice partially through inhibition of the brain-derived neurotrophic factor signaling pathway in the hippocampus and amygdala.
Molecular pain
Liu Z,Liu F,Liu X,Ma C,Zhao J
Mon Jan 14 00:00:00 EST 2019
Heparanase-driven inflammation from the AGEs-stimulated macrophages changes the functions of glomerular endothelial cells.
Diabetes research and clinical practice
Xu G,Qin Q,Yang M,Qiao Z,Gu Y,Niu J
Wed Feb 01 00:00:00 EST 2017
Heparanase-driven inflammation from the AGEs-stimulated macrophages changes the functions of glomerular endothelial cells.
Diabetes research and clinical practice
Xu G,Qin Q,Yang M,Qiao Z,Gu Y,Niu J
Wed Feb 01 00:00:00 EST 2017
Salusin-β Is Involved in Diabetes Mellitus-Induced Endothelial Dysfunction via Degradation of Peroxisome Proliferator-Activated Receptor Gamma.
Oxidative medicine and cellular longevity
Sun HJ,Chen D,Wang PY,Wan MY,Zhang CX,Zhang ZX,Lin W,Zhang F
Fri Aug 17 00:00:00 EDT 2018
Salusin-β Is Involved in Diabetes Mellitus-Induced Endothelial Dysfunction via Degradation of Peroxisome Proliferator-Activated Receptor Gamma.
Oxidative medicine and cellular longevity
Sun HJ,Chen D,Wang PY,Wan MY,Zhang CX,Zhang ZX,Lin W,Zhang F
Fri Aug 17 00:00:00 EDT 2018
Rapid allergen-induced interleukin-17 and interferon-γ secretion by skin-resident memory CD8+ T cells.
Contact dermatitis
Schmidt JD,Ahlström MG,Johansen JD,Dyring-Andersen B,Agerbeck C,Nielsen MM,Poulsen SS,Woetmann A,Ødum N,Thomsen AR,Geisler C,Bonefeld CM
Sat Apr 01 00:00:00 EDT 2017
Rapid allergen-induced interleukin-17 and interferon-γ secretion by skin-resident memory CD8+ T cells.
Contact dermatitis
Schmidt JD,Ahlström MG,Johansen JD,Dyring-Andersen B,Agerbeck C,Nielsen MM,Poulsen SS,Woetmann A,Ødum N,Thomsen AR,Geisler C,Bonefeld CM
Sat Apr 01 00:00:00 EDT 2017
Adulthood Exposure to Lipopolysaccharide Exacerbates the Neurotoxic and Inflammatory Effects of Rotenone in the Substantia Nigra.
Frontiers in molecular neuroscience
Huang C,Zhu L,Li H,Shi FG,Wang GQ,Wei YZ,Liu J,Zhang F
Wed Sep 30 00:00:00 EDT 2020
Adulthood Exposure to Lipopolysaccharide Exacerbates the Neurotoxic and Inflammatory Effects of Rotenone in the Substantia Nigra.
Frontiers in molecular neuroscience
Huang C,Zhu L,Li H,Shi FG,Wang GQ,Wei YZ,Liu J,Zhang F
Wed Sep 30 00:00:00 EDT 2020
Role of NF-κB/GATA3 in the inhibition of lysyl oxidase by IL-1β in human amnion fibroblasts.
Immunology and cell biology
Zhang C,Wang W,Liu C,Lu J,Sun K
Wed Nov 01 00:00:00 EDT 2017
Role of NF-κB/GATA3 in the inhibition of lysyl oxidase by IL-1β in human amnion fibroblasts.
Immunology and cell biology
Zhang C,Wang W,Liu C,Lu J,Sun K
Wed Nov 01 00:00:00 EDT 2017
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
International immunopharmacology
Gong X,Yang Y,Huang L,Zhang Q,Wan RZ,Zhang P,Zhang B
Mon May 01 00:00:00 EDT 2017
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
International immunopharmacology
Gong X,Yang Y,Huang L,Zhang Q,Wan RZ,Zhang P,Zhang B
Mon May 01 00:00:00 EDT 2017
GRP78 plays an integral role in tumor cell inflammation-related migration induced by M2 macrophages.
Cellular signalling
Zhang L,Li Z,Ding G,La X,Yang P,Li Z
Fri Sep 01 00:00:00 EDT 2017
GRP78 plays an integral role in tumor cell inflammation-related migration induced by M2 macrophages.
Cellular signalling
Zhang L,Li Z,Ding G,La X,Yang P,Li Z
Fri Sep 01 00:00:00 EDT 2017
Neuroprotective Effect of Chitosan Oligosaccharide on Hypoxic-Ischemic Brain Damage in Neonatal Rats.
Neurochemical research
Wu W,Wei W,Lu M,Zhu X,Liu N,Niu Y,Sun T,Li Y,Yu J
Wed Nov 01 00:00:00 EDT 2017
Neuroprotective Effect of Chitosan Oligosaccharide on Hypoxic-Ischemic Brain Damage in Neonatal Rats.
Neurochemical research
Wu W,Wei W,Lu M,Zhu X,Liu N,Niu Y,Sun T,Li Y,Yu J
Wed Nov 01 00:00:00 EDT 2017
Rapamycin suppresses Aβ25-35- or LPS-induced neuronal inflammation via modulation of NF-κB signaling.
Neuroscience
Liu YC,Gao XX,Chen L,You XQ
Tue Jul 04 00:00:00 EDT 2017
Rapamycin suppresses Aβ25-35- or LPS-induced neuronal inflammation via modulation of NF-κB signaling.
Neuroscience
Liu YC,Gao XX,Chen L,You XQ
Tue Jul 04 00:00:00 EDT 2017
Global Transcriptomic Profiling of Cortex and Striatum: Cerebral Injury after Ischemia/Reperfusion in a Mouse Model.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Zhao Z,Lu Z,Sun X,Zhao T,Zhang J,Zhou C,Zheng X,Zhang H,Shi G
Sat Jul 01 00:00:00 EDT 2017
Global Transcriptomic Profiling of Cortex and Striatum: Cerebral Injury after Ischemia/Reperfusion in a Mouse Model.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Zhao Z,Lu Z,Sun X,Zhao T,Zhang J,Zhou C,Zheng X,Zhang H,Shi G
Sat Jul 01 00:00:00 EDT 2017
NLRP3 Gene Deletion Attenuates Angiotensin II-Induced Phenotypic Transformation of Vascular Smooth Muscle Cells and Vascular Remodeling.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Ren XS,Tong Y,Ling L,Chen D,Sun HJ,Zhou H,Qi XH,Chen Q,Li YH,Kang YM,Zhu GQ
Mon Mar 12 00:00:00 EDT 2018
NLRP3 Gene Deletion Attenuates Angiotensin II-Induced Phenotypic Transformation of Vascular Smooth Muscle Cells and Vascular Remodeling.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Ren XS,Tong Y,Ling L,Chen D,Sun HJ,Zhou H,Qi XH,Chen Q,Li YH,Kang YM,Zhu GQ
Mon Mar 12 00:00:00 EDT 2018
Impact of prenatal cold stress on placental physiology, inflammatory response, and apoptosis in rats.
Oncotarget
Lian S,Guo J,Wang L,Li W,Wang J,Ji H,Kong F,Xu B,Li S,Yang H
Fri Dec 29 00:00:00 EST 2017
Impact of prenatal cold stress on placental physiology, inflammatory response, and apoptosis in rats.
Oncotarget
Lian S,Guo J,Wang L,Li W,Wang J,Ji H,Kong F,Xu B,Li S,Yang H
Fri Dec 29 00:00:00 EST 2017
Melatonin attenuated the brain damage and cognitive impairment partially through MT2 melatonin receptor in mice with chronic cerebral hypoperfusion.
Oncotarget
Tsai TH,Lin CJ,Chua S,Chung SY,Yang CH,Tong MS,Hang CL
Tue Sep 26 00:00:00 EDT 2017
Melatonin attenuated the brain damage and cognitive impairment partially through MT2 melatonin receptor in mice with chronic cerebral hypoperfusion.
Oncotarget
Tsai TH,Lin CJ,Chua S,Chung SY,Yang CH,Tong MS,Hang CL
Tue Sep 26 00:00:00 EDT 2017
Suppression of MyD88-dependent signaling alleviates neuropathic pain induced by peripheral nerve injury in the rat.
Journal of neuroinflammation
Liu F,Wang Z,Qiu Y,Wei M,Li C,Xie Y,Shen L,Huang Y,Ma C
Fri Mar 31 00:00:00 EDT 2017
Possible involvement of the oxLDL/LOX-1 system in the pathogenesis and progression of human intervertebral disc degeneration or herniation.
Scientific reports
Li X,Wang X,Hu Z,Chen Z,Li H,Liu X,Yong ZY,Wang S,Wei Z,Han Y,Tan J,Li C,He XB,Sun G,Wu D,Li L
Mon Aug 07 00:00:00 EDT 2017
Possible involvement of the oxLDL/LOX-1 system in the pathogenesis and progression of human intervertebral disc degeneration or herniation.
Scientific reports
Li X,Wang X,Hu Z,Chen Z,Li H,Liu X,Yong ZY,Wang S,Wei Z,Han Y,Tan J,Li C,He XB,Sun G,Wu D,Li L
Mon Aug 07 00:00:00 EDT 2017
Naoling decoction restores cognitive function by inhibiting the neuroinflammatory network in a rat model of Alzheimer's disease.
Oncotarget
Xia Z,Peng W,Cheng S,Zhong B,Sheng C,Zhang C,Gong W,Cheng S,Li J,Wang Z
Tue Jun 27 00:00:00 EDT 2017
Naoling decoction restores cognitive function by inhibiting the neuroinflammatory network in a rat model of Alzheimer's disease.
Oncotarget
Xia Z,Peng W,Cheng S,Zhong B,Sheng C,Zhang C,Gong W,Cheng S,Li J,Wang Z
Tue Jun 27 00:00:00 EDT 2017
Dopamine D2 receptor signalling controls inflammation in acute pancreatitis via a PP2A-dependent Akt/NF-κB signalling pathway.
British journal of pharmacology
Han X,Li B,Ye X,Mulatibieke T,Wu J,Dai J,Wu D,Ni J,Zhang R,Xue J,Wan R,Wang X,Hu G
Fri Dec 01 00:00:00 EST 2017
Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure in mice.
Oncotarget
Yang Y,Gong XB,Huang LG,Wang ZX,Wan RZ,Zhang P,Zhang QY,Chen Z,Zhang BS
Tue May 09 00:00:00 EDT 2017
Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure in mice.
Oncotarget
Yang Y,Gong XB,Huang LG,Wang ZX,Wan RZ,Zhang P,Zhang QY,Chen Z,Zhang BS
Tue May 09 00:00:00 EDT 2017
NLRP3 inflammasome activation contributes to VSMC phenotypic transformation and proliferation in hypertension.
Cell death & disease
Sun HJ,Ren XS,Xiong XQ,Chen YZ,Zhao MX,Wang JJ,Zhou YB,Han Y,Chen Q,Li YH,Kang YM,Zhu GQ
Thu Oct 05 00:00:00 EDT 2017
NLRP3 inflammasome activation contributes to VSMC phenotypic transformation and proliferation in hypertension.
Cell death & disease
Sun HJ,Ren XS,Xiong XQ,Chen YZ,Zhao MX,Wang JJ,Zhou YB,Han Y,Chen Q,Li YH,Kang YM,Zhu GQ
Thu Oct 05 00:00:00 EDT 2017
Aliskiren Improves Ischemia- and Oxygen Glucose Deprivation-Induced Cardiac Injury through Activation of Autophagy and AMP-Activated Protein Kinase.
Frontiers in pharmacology
Chiang MH,Liang CJ,Liu CW,Pan BJ,Chen WP,Yang YF,Lee IT,Tsai JS,Lee CW,Chen YL
Thu Oct 01 00:00:00 EDT 2020
Aliskiren Improves Ischemia- and Oxygen Glucose Deprivation-Induced Cardiac Injury through Activation of Autophagy and AMP-Activated Protein Kinase.
Frontiers in pharmacology
Chiang MH,Liang CJ,Liu CW,Pan BJ,Chen WP,Yang YF,Lee IT,Tsai JS,Lee CW,Chen YL
Thu Oct 01 00:00:00 EDT 2020
Angiotensin(1-7) attenuated Angiotensin II-induced hepatocyte EMT by inhibiting NOX-derived H2O2-activated NLRP3 inflammasome/IL-1β/Smad circuit.
Free radical biology & medicine
Zhang LL,Huang S,Ma XX,Zhang WY,Wang D,Jin SY,Zhang YP,Li Y,Li X
Mon Aug 01 00:00:00 EDT 2016
Angiotensin(1-7) attenuated Angiotensin II-induced hepatocyte EMT by inhibiting NOX-derived H2O2-activated NLRP3 inflammasome/IL-1β/Smad circuit.
Free radical biology & medicine
Zhang LL,Huang S,Ma XX,Zhang WY,Wang D,Jin SY,Zhang YP,Li Y,Li X
Mon Aug 01 00:00:00 EDT 2016
Dendrobium officinale Kimura et Migo attenuates diabetic cardiomyopathy through inhibiting oxidative stress, inflammation and fibrosis in streptozotocin-induced mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhang Z,Zhang D,Dou M,Li Z,Zhang J,Zhao X
Thu Dec 01 00:00:00 EST 2016
Dendrobium officinale Kimura et Migo attenuates diabetic cardiomyopathy through inhibiting oxidative stress, inflammation and fibrosis in streptozotocin-induced mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhang Z,Zhang D,Dou M,Li Z,Zhang J,Zhao X
Thu Dec 01 00:00:00 EST 2016
15d-PGJ2 alleviates ConA-induced acute liver injury in mice by up-regulating HO-1 and reducing hepatic cell autophagy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Chen K,Li J,Li S,Feng J,Wu L,Liu T,Zhang R,Xu S,Cheng K,Zhou Y,Zhou S,Wang F,Dai W,Xia Y,Lu J,Zhou Y,Guo C
Sun May 01 00:00:00 EDT 2016
15d-PGJ2 alleviates ConA-induced acute liver injury in mice by up-regulating HO-1 and reducing hepatic cell autophagy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Chen K,Li J,Li S,Feng J,Wu L,Liu T,Zhang R,Xu S,Cheng K,Zhou Y,Zhou S,Wang F,Dai W,Xia Y,Lu J,Zhou Y,Guo C
Sun May 01 00:00:00 EDT 2016
A recombinant TGF-β1 vaccine ameliorates diabetic nephropathy in OLETF rats.
Immunotherapy
Zhang H,Wang H,Yan M,Zhao T,Lu X,Zhu B,Gong Y,Li P
Thu Sep 01 00:00:00 EDT 2016
A recombinant TGF-β1 vaccine ameliorates diabetic nephropathy in OLETF rats.
Immunotherapy
Zhang H,Wang H,Yan M,Zhao T,Lu X,Zhu B,Gong Y,Li P
Thu Sep 01 00:00:00 EDT 2016
New insights into salvianolic acid A action: Regulation of the TXNIP/NLRP3 and TXNIP/ChREBP pathways ameliorates HFD-induced NAFLD in rats.
Scientific reports
Ding C,Zhao Y,Shi X,Zhang N,Zu G,Li Z,Zhou J,Gao D,Lv L,Tian X,Yao J
Mon Jun 27 00:00:00 EDT 2016
New insights into salvianolic acid A action: Regulation of the TXNIP/NLRP3 and TXNIP/ChREBP pathways ameliorates HFD-induced NAFLD in rats.
Scientific reports
Ding C,Zhao Y,Shi X,Zhang N,Zu G,Li Z,Zhou J,Gao D,Lv L,Tian X,Yao J
Mon Jun 27 00:00:00 EDT 2016
AIM2 inhibits autophagy and IFN-β production during M. bovis infection.
Oncotarget
Liu C,Yue R,Yang Y,Cui Y,Yang L,Zhao D,Zhou X
Tue Jul 26 00:00:00 EDT 2016
Inflammatory Stress Sensitizes the Liver to Atorvastatin-Induced Injury in ApoE-/- Mice.
PloS one
Wu W,Zhao L,Yang P,Zhou W,Li B,Moorhead JF,Varghese Z,Ruan XZ,Chen Y
Wed Jul 19 00:00:00 EDT 2017
Inflammatory Stress Sensitizes the Liver to Atorvastatin-Induced Injury in ApoE-/- Mice.
PloS one
Wu W,Zhao L,Yang P,Zhou W,Li B,Moorhead JF,Varghese Z,Ruan XZ,Chen Y
Wed Jul 19 00:00:00 EDT 2017
Histone deacetylase inhibitor SAHA attenuates post-seizure hippocampal microglia TLR4/MYD88 signaling and inhibits TLR4 gene expression via histone acetylation.
BMC neuroscience
Hu QP,Mao DA
Wed May 18 00:00:00 EDT 2016
Histone deacetylase inhibitor SAHA attenuates post-seizure hippocampal microglia TLR4/MYD88 signaling and inhibits TLR4 gene expression via histone acetylation.
BMC neuroscience
Hu QP,Mao DA
Wed May 18 00:00:00 EDT 2016
Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice.
International immunopharmacology
Shi Q,Song X,Fu J,Su C,Xia X,Song E,Song Y
Tue Dec 01 00:00:00 EST 2015
Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice.
International immunopharmacology
Shi Q,Song X,Fu J,Su C,Xia X,Song E,Song Y
Tue Dec 01 00:00:00 EST 2015
P2X7R is involved in the progression of atherosclerosis by promoting NLRP3 inflammasome activation.
International journal of molecular medicine
Peng K,Liu L,Wei D,Lv Y,Wang G,Xiong W,Wang X,Altaf A,Wang L,He D,Wang H,Qu P
Fri May 01 00:00:00 EDT 2015
P2X7R is involved in the progression of atherosclerosis by promoting NLRP3 inflammasome activation.
International journal of molecular medicine
Peng K,Liu L,Wei D,Lv Y,Wang G,Xiong W,Wang X,Altaf A,Wang L,He D,Wang H,Qu P
Fri May 01 00:00:00 EDT 2015
The quantum of initial transformed cells potentially modulates the type of local inflammation mechanism elicited by surrounding normal epithelial tissues and systemic immune pattern for tumor arrest or progression.
Journal of Cancer
Owusu L,Wang B,Du Y,Li W,Xin Y
Tue Jan 06 00:00:00 EST 2015
The quantum of initial transformed cells potentially modulates the type of local inflammation mechanism elicited by surrounding normal epithelial tissues and systemic immune pattern for tumor arrest or progression.
Journal of Cancer
Owusu L,Wang B,Du Y,Li W,Xin Y
Tue Jan 06 00:00:00 EST 2015
Expression of beclin-1 in the microenvironment of invasive ductal carcinoma of the breast: correlation with prognosis and the cancer-stromal interaction.
PloS one
Morikawa A,Takeuchi T,Kito Y,Saigo C,Sakuratani T,Futamura M,Yoshida K
Tue Feb 02 00:00:00 EST 2016
Expression of beclin-1 in the microenvironment of invasive ductal carcinoma of the breast: correlation with prognosis and the cancer-stromal interaction.
PloS one
Morikawa A,Takeuchi T,Kito Y,Saigo C,Sakuratani T,Futamura M,Yoshida K
Tue Feb 02 00:00:00 EST 2016
Aging increases the susceptibility of cisplatin-induced nephrotoxicity.
Age (Dordrecht, Netherlands)
Wen J,Zeng M,Shu Y,Guo D,Sun Y,Guo Z,Wang Y,Liu Z,Zhou H,Zhang W
Tue Dec 01 00:00:00 EST 2015
Aging increases the susceptibility of cisplatin-induced nephrotoxicity.
Age (Dordrecht, Netherlands)
Wen J,Zeng M,Shu Y,Guo D,Sun Y,Guo Z,Wang Y,Liu Z,Zhou H,Zhang W
Tue Dec 01 00:00:00 EST 2015
Inhibition of HMGB1 release via salvianolic acid B-mediated SIRT1 up-regulation protects rats against non-alcoholic fatty liver disease.
Scientific reports
Zeng W,Shan W,Gao L,Gao D,Hu Y,Wang G,Zhang N,Li Z,Tian X,Xu W,Peng J,Ma X,Yao J
Tue Nov 03 00:00:00 EST 2015
Inhibition of HMGB1 release via salvianolic acid B-mediated SIRT1 up-regulation protects rats against non-alcoholic fatty liver disease.
Scientific reports
Zeng W,Shan W,Gao L,Gao D,Hu Y,Wang G,Zhang N,Li Z,Tian X,Xu W,Peng J,Ma X,Yao J
Tue Nov 03 00:00:00 EST 2015
Tongxinluo inhibits vascular inflammation and neointimal hyperplasia through blockade of the positive feedback loop between miR-155 and TNF-α.
American journal of physiology. Heart and circulatory physiology
Zhang RN,Zheng B,Li LM,Zhang J,Zhang XH,Wen JK
Fri Aug 15 00:00:00 EDT 2014
Tongxinluo inhibits vascular inflammation and neointimal hyperplasia through blockade of the positive feedback loop between miR-155 and TNF-α.
American journal of physiology. Heart and circulatory physiology
Zhang RN,Zheng B,Li LM,Zhang J,Zhang XH,Wen JK
Fri Aug 15 00:00:00 EDT 2014
Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.
Toxicology and applied pharmacology
Xu D,Hu L,Su C,Xia X,Zhang P,Fu J,Wang W,Xu D,Du H,Hu Q,Song E,Song Y
Wed Oct 15 00:00:00 EDT 2014
Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.
Toxicology and applied pharmacology
Xu D,Hu L,Su C,Xia X,Zhang P,Fu J,Wang W,Xu D,Du H,Hu Q,Song E,Song Y
Wed Oct 15 00:00:00 EDT 2014
Mulberroside A protects against ischemic impairment in primary culture of rat cortical neurons after oxygen-glucose deprivation followed by reperfusion.
Journal of neuroscience research
Wang CP,Zhang LZ,Li GC,Shi YW,Li JL,Zhang XC,Wang ZW,Ding F,Liang XM
Tue Jul 01 00:00:00 EDT 2014
Impaired autophagy contributes to adverse cardiac remodeling in acute myocardial infarction.
PloS one
Wu X,He L,Chen F,He X,Cai Y,Zhang G,Yi Q,He M,Luo J
Tue Jul 14 00:00:00 EDT 2015
Impaired autophagy contributes to adverse cardiac remodeling in acute myocardial infarction.
PloS one
Wu X,He L,Chen F,He X,Cai Y,Zhang G,Yi Q,He M,Luo J
Tue Jul 14 00:00:00 EDT 2015
Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation.
Immunity
Yan Y,Jiang W,Spinetti T,Tardivel A,Castillo R,Bourquin C,Guarda G,Tian Z,Tschopp J,Zhou R
Thu Jun 27 00:00:00 EDT 2013
Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation.
Immunity
Yan Y,Jiang W,Spinetti T,Tardivel A,Castillo R,Bourquin C,Guarda G,Tian Z,Tschopp J,Zhou R
Thu Jun 27 00:00:00 EDT 2013
NDGA reduces secondary damage after spinal cord injury in rats via anti-inflammatory effects.
Brain research
Xue H,Zhang XY,Liu JM,Song Y,Liu TT,Chen D
Fri Jun 21 00:00:00 EDT 2013
NDGA reduces secondary damage after spinal cord injury in rats via anti-inflammatory effects.
Brain research
Xue H,Zhang XY,Liu JM,Song Y,Liu TT,Chen D
Fri Jun 21 00:00:00 EDT 2013