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Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Enhancer trap locus homolog 2; Etl-2; IL-11 receptor subunit alpha; IL-11 receptor subunit alpha-1; IL-11R subunit alpha; IL-11R subunit alpha-1; IL-11R-alpha-1; Il-11ra-alpha; IL-11RA1; interleukin 11 receptor, alpha; interleukin 11 receptor, alpha chain 2; interleukin-11 receptor alpha chain; Interleukin-11 receptor subunit alpha; Interleukin-11 receptor subunit alpha-1; locus 2; Novel cytokine receptor 1; NR-1; sIL11RA
基因别名: AI314697; CRSDA; Etl2; GP130; Il-11ra; IL11RA; Il11ra1; Il11ra2; NR1
UniProt ID: (Human) Q14626, (Mouse) Q64385
Entrez Gene ID: (Human) 3590, (Mouse) 16157