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AA Sequence of recombinant protein: MQPRSPKSKR KGQGRPGPLA PGPHQVPLDL VSRMKPYARM EEYERNIEEM VAQLRNSSEL AQRKCEVNLQ LWMSNKRSLS PWGYSINHDP SRIPVDLPEA RCLCLGCVNP FTMQEDRSMV SVPVFSQVPV RRRLCPPPPR TGPCRQRAVM ETIAVGCTCI F.
Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human IL-17B. Anti-Human IL-17B-specific antibody was purified by affinity chromatography employing an immobilized Human IL-17B matrix.
Sandwich ELISA: To detect Human IL-17B by sandwich ELISA (using 100 µL/well antibody solution) a concentration of 0.5-2.0 µg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human IL-17B (500-P248Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human IL-17B.
Western Blot: To detect Human IL-17B by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 µg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human IL-17B is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cytokine Zcyto7; cytokine-like protein ZCYTO7; IL-17B; IL-20; interleukin 20; interleukin-17 beta; Interleukin-17B; Interleukin-20; Interleukin20; neuronal interleukin-17 related factor; Neuronal interleukin-17-related factor
基因别名: IL-17B; IL-20; IL17B; IL20; NIRF; UNQ516/PRO1031; ZCYTO7
UniProt ID: (Human) Q9UHF5
Entrez Gene ID: (Human) 27190