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IL17RB Antibody (PA5-47051) in WB
Western blot analysis of IL17RB in mouse liver tissue and mouse spleen tissue (negative control). Samples were incubated in IL17RB polyclonal antibody (Product # PA5-47051) using a dilution of 1 µg/mL followed by a HRP-conjugated Anti-Goat IgG secondary antibody. A specific band was detected for IL‚17 RB at approximately 50 kDa (as indicated). This experiment was conducted under reducing conditions.
产品信息
PA5-47051
产品规格
种属反应
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant mouse IL-17RB Arg18-Gly286
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2577152
产品详细信息
In direct ELISAs, less than 1% cross-reactivity with recombinant mouse IL-17 R and recombinant human IL-17 R is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
Recently, a number of cytokines belonging to the interleukin (IL)-17 family have been identified. These are termed as IL-17B, IL-17C (1) and IL-17E. IL-17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis, multiple sclerosis, and promotion of tumor growth. IL-17B, C, and E like IL-17 are able to induce proinflammatory responses. However, they do not bind to the IL-17 receptor suggesting that additional IL-17R related receptor might exist. Receptor for IL-17B and IL-17E has been independently isolated and has been designated as EV127 (in mouse) and IL-17Rh1 (in human), respectively. IL-17E induces activation of NF-kB pathway and like IL-17 also induces production of IL-8. IL-17Rh1 mRNA is highly expressed in Kidney and liver and at moderate level in small intestine, colon, and brain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ecotropic viral integration site 27; IL-17 receptor B; IL-17 receptor homolog 1; IL-17B receptor; IL-17ER; IL-17RB; interleukin 17B receptor; Interleukin-17 receptor B; Interleukin-17B receptor; MGC138900; MGC138901; MGC5245; ZCYTO7
基因别名: Evi27; IL-17ER; IL-17Rh1; Il17br; Il17rb; IL17RH1
UniProt ID: (Mouse) Q9JIP3
Entrez Gene ID: (Mouse) 50905
