Invitrogen

IL17RD Polyclonal Antibody

IL17RD Antibody in Flow Cytometry (Flow)

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IL17RD Antibody (PA5-47288) in Flow

Flow cytometry of IL17RD in HEK293 human cell line transfected with mouse IL-17 RD/SEF. Samples were incubated in IL17RD polyclonal antibody (Product # PA5-47288) or isotype control antibody followed by Phycoerythrin-conjugated Anti-Goat IgG Secondary Antibody.

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产品信息

PA5-47288

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.1 µg/mL

免疫组化 (IHC)

5-15 µg/mL

流式细胞分析 (Flow)

0.25 µg per million cells

产品规格

种属反应

Mouse

宿主/亚型

Goat / IgG

分类

Polyclonal

类型

Antibody

抗原

Mouse myeloma cell line NS0-derived recombinant mouse IL-17RD/SEF Gly28-Arg299

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS with 5% trehalose

内含物

No Preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2606763

产品详细信息

In direct ELISAs, approximately 40% cross-reactivity with recombinant human IL-17 RD is observed and less than 1% cross-reactivity with recombinant mouse (rm) IL-17 RC and rmIL-17B R is observed.

Reconstitute at 0.2 mg/mL in sterile PBS.

靶标信息

Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK. Mediates JNK activation and may be involved in apoptosis. Might have a role in the early stages of fate specification of GnRH-secreting neurons.

仅用于科研。不用于诊断过程。未经明确授权不得转售。