Invitrogen

IL17RE Polyclonal Antibody

产品信息

PA5-53891

应用

建议稀释比

已发表文章

免疫组化 (IHC)

1:50-1:200

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human IL17RE. Recombinant protein control fragment (Product #RP-90384).

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2642689

产品详细信息

Immunogen sequence: EKSHHISIPS PDISHKGLRS KRTQPSDPET WESLPRLDSQ RHGGPEFSFD LLPEARAIRV TISSGPEVSV RLCHQWALEC EELSSPYDVQ KIVSGGHTVE LPYEFLLPCL CMEASYLQED TVRRKKCPFQ SWPEAYGSDF WKSVHFTDYS

Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 75%.

靶标信息

The interleukin 17 receptor E (IL-17RE) shares limited similarity to the receptor of IL-17A, a ubiquitous type I membrane glycoprotein that with IL-17A plays a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. IL-17RE is the functional receptor of IL-17C and has been suggested to mediate mucosal immunity to infection with intestinal pathogens. IL-17C is produced by epithelia in response to bacterial challenge and binds to a receptor complex formed by IL-17RE and IL-17RA on the epithelial cell surface, thereby regulating the immune function of epithelial cells in an autocrine manner.

仅用于科研。不用于诊断过程。未经明确授权不得转售。