Search Thermo Fisher Scientific
Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji.
Predicted reactivity: Mouse (95%), Rat (82%), Xenopus laevis (88%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZp781N0678; IMP (inosine 5'-monophosphate) dehydrogenase 1; IMP (inosine monophosphate) dehydrogenase 1; IMP dehydrogenase 1; IMPD 1; IMPDH 1; IMPDH-I; Inosine-5'-monophosphate dehydrogenase 1
基因别名: IMPD; IMPD1; IMPDH-I; IMPDH1; LCA11; RP10; sWSS2608
UniProt ID: (Human) P20839
Entrez Gene ID: (Human) 3614
分子生物学功能:
dehydrogenase