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Immunogen sequence: EVVKLIFRES DNDRKVMLQL EKKLFDYFNQ EVFRDNNGTA LLEFDKELSV FKDRLYELDI SFPPSYPYSE DARQGEQYMN TRCPAWCDRI LMSPSAKELV LRSESEEKVV TYDHIGPNVC MGDHKPVFL
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.
The protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 43 kDa inositol polyphosphate 5-phophatase; 43 kDa inositol polyphosphate 5-phosphatase; 5PTase; CTCL tumor antigen HD-CL-02; DKFZp434A1721; Inositol polyphosphate-5-phosphatase A; inositol polyphosphate-5-phosphatase, 40kD; inositol polyphosphate-5-phosphatase, 40kDa; inositol trisphosphate-5-phosphatase, 40kD; InsP3 5-phosphatase; MGC116947; MGC116949; Type I inositol 1,4,5-trisphosphate 5-phosphatase; type I inositol-1,4,5-trisphosphate 5-phophatase; type I inositol-1,4,5-trisphosphate 5-phosphatase
基因别名: 5PTASE; INPP5A
UniProt ID: (Human) Q14642
Entrez Gene ID: (Human) 3632