Invitrogen

ITGA3 Polyclonal Antibody

高级验证

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

查看其他24个CD49c (Integrin alpha 3)抗体

说明书

实验方案

技术支持

说明书

实验方案

技术支持

抗体检测数据 (3)
高级验证 (1)

ITGA3 Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 4

ITGA3 Antibody (PA5-86556) in ICC/IF

Immunofluorescence analysis of ITGA3 was performed using 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with ITGA3 Polyclonal Antibody (Product # PA5-86556) at 1:100 dilution in 0.1% BSA, incubated at 4 degree celsius overnight and then labeled with Donkey anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus 488 (Product # A32790),... View More

Product Image Gallery

ITGA3 Antibody — Antibody specificity was demonstrated by detection of differential basal expression of the target across cell lines and tissues owing to their inherent genetic constitution. Relative expression of ITGA3 was observed in U-87 MG, A549, A-431, HeLa, Mouse Lung and Rat Lung in comparison to Daudi, HEK-293, K-562, Mouse skeletal muscle and Rat skeletal muscle using Anti-ITGA3 Polyclonal Antibody (Product # PA5-86556) in Western Blot. {RE}

产品信息

PA5-86556

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

免疫细胞化学 (ICC/IF)

1:100

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide, corresponding to amino acids 500-550 of Human Integrin alpha-3.

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2803328

产品详细信息

Purity is > 95% by SDS-PAGE.

靶标信息

ITGA3 (INTEGRIN, ALPHA-3), also called CD49C, VLA3 or GAPB3, is a protein that in humans is encoded by the ITGA3 gene. ITGA3 is an integrin alpha subunit which is also a member of the family of cell surface adhesion molecules. ITGA3 is mapped to chromosome 17 and its exact cytogenetic location is 17q21.33. ITGA3 makes up half of the alpha3beta1 integrin duplex that plays a role in neural migration and corticogenesis together with beta-1 subunit. A functional link between DAB1 phosphorylation and ITGA3 signaling drives the timely detachment of migrating neurons from radial glial fibers. Expression of human ITGA3 increased the infectivity of virus for Chinese hamster ovary cells. ITGA3 also contains 13 potential N-glycosylation sites, 2 potential cleavage sites, and the 7 N-terminal repeating units characteristic of ITGAs. Recombinant ITGA3 is expressed as a 150-kD protein as the same size as the native protein by the western blot analysis.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: alpha 3 subunit of VLA-3 receptor; Alpha3 integrin; antigen CD49C; antigen identified by monoclonal antibody J143; CD49 antigen-like family member C; CD49c; CD49c antigen; FLJ34631; FLJ34704; FRP-2; Galactoprotein B3; GAPB3; integrin alpha 3; Integrin alpha-3; Integrin alpha3; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor); testicular tissue protein Li 96; testicular tissue protein Li 98; very late activation protein 3 receptor, alpha-3 subunit; VLA-3 subunit alpha

查看更多收起

基因别名: AA407068; CD49C; FRP-2; GAP-B3; GAPB3; ILNEB; ITGA3; MSK18; VCA-2; VL3A; VLA3a

查看更多收起

UniProt ID: (Human) P26006, (Mouse) Q62470

查看更多收起

Entrez Gene ID: (Human) 3675, (Rat) 360606, (Mouse) 16400

查看更多收起

功能