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In direct ELISAs, approximately 35% cross-reactivity with recombinant mouse Integrin beta 6 is observed and less than 5% cross-reactivity with recombinant human (rh) Integrin beta 3 and rhIntegrin beta 5 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
ITGB6 (Integrin alpha-V/beta-6) is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalization of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: integrin beta 6; Integrin beta-6; integrin, beta 6
基因别名: 2210409C20Rik; 4831415H04Rik; AI1H; ITGB6
UniProt ID: (Human) P18564, (Mouse) Q9Z0T9
Entrez Gene ID: (Human) 3694, (Mouse) 16420