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ITPA Antibody (MA5-55475) in WB
Western Blot analysis of various lysates using ITPA Recombinant Monoclonal Antibody (Product # MA5-55475) at 1:1,000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10,000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 180s.
产品信息
MA5-55475
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
2O6K5
抗原
A synthetic peptide corresponding to a sequence within amino acids 70-150 of human ITPA.
偶联物
形式
Liquid
浓度
1.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
产品详细信息
Immunogen Sequence: VEDTCLCFNA LGGLPGPYIK WFLEKLKPEG LHQLLAGFED KSAYALCTFA LSTGDPSQPV RLFRGRTSGR IVAPRGCQDF G
靶标信息
Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: inosine triphosphatase (nucleoside triphosphate pyrophosphatase); Inosine triphosphate pyrophosphatase; inosine triphosphate pyrophosphohydrolase; ITPase; My049 protein; Non-canonical purine NTP pyrophosphatase; Non-standard purine NTP pyrophosphatase; NTPase; nucleoside triphosphate pyrophosphatase; Nucleoside-triphosphate diphosphatase; Nucleoside-triphosphate pyrophosphatase; Putative oncogene protein hlc14-06-p
基因别名: 2010016I08Rik; AU020102; C20orf37; dJ794I6.3; HLC14-06-P; Itp; ITPA; ITPase; My049; NTPase; OK/SW-cl.9
UniProt ID: (Human) Q9BY32, (Mouse) Q9D892
Entrez Gene ID: (Human) 3704, (Mouse) 16434
