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This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Immunogen sequence: ADRSMEKKKG EPRTRAEARP WVDEDLKDSS DLHQAEEDAD EWQESEENVE HIPFSHNHYP EK
Highest antigen sequence identity to the following orthologs: Mouse - 66%, Rat - 65%.
This gene encodes an enzyme that catalyzes the oxidative NADPH-dependent deiodination of mono- and diiodotyrosine, which are the halogenated byproducts of thyroid hormone production. The N-terminus of the protein functions as a membrane anchor. Mutations in this gene cause congenital hypothyroidism due to dyshormonogenesis type 4, which is also referred to as deiodinase deficiency, or iodotyrosine dehalogenase deficiency, or thyroid hormonogenesis type 4. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: dJ422F24.1; Iodotyrosine dehalogenase 1; Iodotyrosine deiodinase 1; IYD-1
基因别名: C6orf71; DEHAL1; IYD; IYD-1; TDH4
UniProt ID: (Human) Q6PHW0
Entrez Gene ID: (Human) 389434