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产品信息
14678-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
IgG light chain (Kappa) Fusion Protein Ag6389 (1-234 aa encoded by BC030813)
偶联物
形式
Liquid
浓度
0.28 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody detects the light chain (Kappa) of human IgG.
Immunogen sequence: MEAPAQLLF LLLLWLPDTT GEIVMTQSPA TLSVSPGERA TLSCRASQSV TSNLAWYQQT PGQSPRLVIY GASSRASGVP ARFSGSGSGT EFTLTISSLQ SEDFAVYYCQ QYNKWPHTFG QGTKLDIKRT VAAPSVFIFP PSDEQLKSGT ASVVCLLNNF YPREAKVQWK VDNALQSGNS QESVTEQDSK DSTYSLSSTL TLSKADYEKH KVYACEVTHQ GLSSPVTKSF NRGEC (1-234 aa encoded by BC030813)
靶标信息
Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five types) and two light chains (kappa, lambda; both having a molecular weight of 22.5 kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30. Antibodies to the kappa light chain are reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: ig kappa chain c region; Immunoglobulin K; immunoglobulin kappa light chain; Kappa LC
基因别名: HCAK1; Igk-C; IGK@; IGKCD; kappa; Km
Entrez Gene ID: (Human) 50802, (Human) 3514, (Mouse) 243469, (Mouse) 16071
