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Inhibins and activins are involved in regulating a number of functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth depending on their subunit composition. Activins oppose the funtions of inhibins. Inhibins are predominantly expressed in liver, uterus and ovary tissue, but also in benign prostatic hyperplasia. Inhibin A, a dimer of alpha and beta-A, and inhibin B, a dimer of alpha and beta-B, have been shown to inhibit the secretion of follicle stimulating hormone. Inhibin beta-C forms a homodimer and its expression is predominant in adult liver and in benign prostatic hyperplasia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Activin beta-C chain; activin/inhibin beta C; Inhibin beta C chain; inhibin, beta C
基因别名: IHBC; INHBC
UniProt ID: (Human) P55103, (Rat) Q9WUK5, (Mouse) P55104
Entrez Gene ID: (Human) 3626, (Rat) 64549, (Mouse) 16325