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产品信息
PA5-82170
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Anitgen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2789331
产品详细信息
Immunogen sequence: ANNMQEAQSI DEIYKYDKKQ QQEILAAKPW TKDHHYFKYC KISALALLKM VMHARSGGNL EVMGLMLGKV DGETMIIMDS FALPVEGTET RVNAQAAAYE YMAAYIENAK QVGRLENAIG WYHSHPGYGC WLS
靶标信息
JAB-1 is a 38 kDa protein which was originally described as a coactivator for cJUN. It is present in a large protein complex called the "Signalosome", which has been proposed to play a signaling role in mammalian cells. This protein complex appears to be analogous to the COP9 complex in plants, which is important in light-mediated plant development. Although the specific function of JAB-1 in this complex is unclear, it has recently been implicated in targeting proteins for degradation by the proteasome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 38 kDa Mov34 homolog; COP9 (constitutive photomorphogenic) homolog, subunit 5; COP9 complex S5; COP9 constitutive photomorphogenic homolog subunit 5; COP9 signalosome complex subunit 5; Jun activation domain-binding protein 1; Jun coactivator; Kip1 C-terminus-interacting protein 2; MGC3149; SGN5; signalosome subunit 5; testis secretory sperm-binding protein Li 231m
基因别名: AI303502; COPS5; CSN5; JAB1; Kic2; MOV-34; Mov34; SGN5
UniProt ID: (Human) Q92905, (Mouse) O35864
Entrez Gene ID: (Human) 10987, (Rat) 312916, (Mouse) 26754
protein deneddylation
nucleotide-excision repair, DNA damage recognition
transcription-coupled nucleotide-excision repair
transcription from RNA polymerase II promoter
translation
translational initiation
cullin deneddylation
protein deubiquitination
positive regulation of transcription from RNA polymerase II promoter
regulation of JNK cascade
regulation of cell cycle
regulation of IRE1-mediated unfolded protein response
exosomal secretion
proteolysis
regulation of transcription, DNA-templated
