JAK2 Polyclonal Antibody

protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding interleukin-12 receptor binding protein binding ATP binding protein C-terminus binding protein kinase binding heme binding type 1 angiotensin receptor binding acetylcholine receptor binding histone kinase activity (H3-Y41 specific) SH2 domain binding histone binding phosphatidylinositol 3-kinase binding insulin receptor substrate binding metal ion binding peptide hormone receptor binding nucleotide binding kinase activity transferase activity transferase activity, transferring phosphorus-containing groups

activation of MAPKK activity activation of cysteine-type endopeptidase activity involved in apoptotic process response to oxidative stress signal transduction enzyme linked receptor protein signaling pathway G-protein coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration JAK-STAT cascade tyrosine phosphorylation of STAT protein STAT protein import into nucleus positive regulation of cell proliferation negative regulation of cell proliferation intrinsic apoptotic signaling pathway in response to oxidative stress hormone-mediated signaling pathway negative regulation of cardiac muscle cell apoptotic process positive regulation of cell-substrate adhesion positive regulation of phosphatidylinositol 3-kinase signaling peptidyl-tyrosine phosphorylation cytokine-mediated signaling pathway negative regulation of cell-cell adhesion myeloid cell differentiation cell differentiation erythrocyte differentiation positive regulation of cell migration axon regeneration mineralocorticoid receptor signaling pathway positive regulation of insulin secretion response to lipopolysaccharide positive regulation of phosphoprotein phosphatase activity positive regulation of interleukin-1 beta production positive regulation of tumor necrosis factor production positive regulation of protein import into nucleus, translocation response to hydroperoxide tumor necrosis factor-mediated signaling pathway host programmed cell death induced by symbiont response to tumor necrosis factor histone H3-Y41 phosphorylation intracellular signal transduction interleukin-12-mediated signaling pathway peptidyl-tyrosine autophosphorylation tyrosine phosphorylation of Stat3 protein tyrosine phosphorylation of Stat5 protein tyrosine phosphorylation of Stat1 protein positive regulation of tyrosine phosphorylation of Stat3 protein positive regulation of tyrosine phosphorylation of Stat5 protein activation of JAK2 kinase activity positive regulation of apoptotic process negative regulation of apoptotic process positive regulation of DNA binding negative regulation of DNA binding negative regulation of neuron apoptotic process positive regulation of nitric oxide biosynthetic process positive regulation of cell differentiation negative regulation of heart contraction positive regulation of transcription from RNA polymerase II promoter response to antibiotic protein autophosphorylation platelet-derived growth factor receptor signaling pathway regulation of inflammatory response positive regulation of inflammatory response positive regulation of peptidyl-tyrosine phosphorylation positive regulation of cell activation positive regulation of sequence-specific DNA binding transcription factor activity positive regulation of nitric-oxide synthase biosynthetic process interferon-gamma-mediated signaling pathway growth hormone receptor signaling pathway JAK-STAT cascade involved in growth hormone signaling pathway positive regulation of growth hormone receptor signaling pathway mammary gland epithelium development response to interleukin-12 cellular response to lipopolysaccharide cellular response to dexamethasone stimulus extrinsic apoptotic signaling pathway activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway positive regulation of apoptotic signaling pathway MAPK cascade adaptive immune response protein phosphorylation apoptotic process movement of cell or subcellular component mesoderm development blood coagulation cell migration actin filament polymerization regulation of cell proliferation regulation of apoptotic process positive regulation of GTPase activity innate immune response regulation of interferon-gamma-mediated signaling pathway immune system process transmembrane receptor protein tyrosine kinase signaling pathway phosphorylation chromatin modification regulation of cell adhesion response to granulocyte macrophage colony-stimulating factor