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JAM2 Antibody (PA5-121251) in WB
Western blot analysis of JAM2 in extracts of various cell lines. Samples were incubated with JAM2 Polyclonal antibody (Product # PA5-121251) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
产品信息
PA5-121251
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 29-238 of human JAM2 (NP_067042.1).
偶联物
形式
Liquid
浓度
0.73 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914823
产品详细信息
Positive test controls include: NIH/3T3, SH-SY5Y, Rat brain, Rat heart. The target is usually found in the following locations: Cell junction, Cell membrane, Single-pass type I membrane protein, tight junction.
Immunogen sequence: FSAPKDQQVV TAVEYQEAIL ACKTPKKTVS SRLEWKKLGR SVSFVYYQQT LQGDFKNRAE MIDFNIRIKN VTRSDAGKYR CEVSAPSEQG QNLEEDTVTL EVLVAPAVPS CEVPSSALSG TVVELRCQDK EGNPAPEYTW FKDGIRLLEN PRLGSQSTNS SYTMNTKTGT LQFNTVSKLD TGEYSCEARN SVGYRRCPGK RMQVDDLNIS
靶标信息
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AU016127; CD322; JAM-2; JAM-B; JAM-IT/VE-JAM; junction adhesion molecule 2; junction adhesion molecule B; junction cell adhesion molecule 2; Junctional adhesion molecule 2; Junctional adhesion molecule B; RP23-253E17.2; Vascular endothelial junction-associated molecule; VE-JAM
基因别名: 1110002N23Rik; 2410030G21Rik; 2410167M24Rik; C21orf43; CD322; JAM-2; JAM-B; JAM2; JAMB; Jcam2; PRO245; UNQ219/PRO245; VE-JAM; VEJAM
UniProt ID: (Human) P57087, (Mouse) Q9JI59
Entrez Gene ID: (Human) 58494, (Mouse) 67374, (Rat) 619374
