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JARID2 Antibody (MA5-38546) in ICC/IF
Immunocytochemistry/Immunofluorescence analysis of JARID2 in HeLa cells using JARID2 Monoclonal Antibody (Product # MA5-38546) (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Product # 35503)
产品信息
MA5-38546
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
7H1B3
抗原
Purified recombinant fragment of human JARID2 (aa: 1097-1246) expressed in E. Coli.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2898458
产品详细信息
This antibody has been tested in indirect ELISA.
靶标信息
Jumonji (JARID2) is a nuclear protein that participates in the negative regulation of cell growth. It is required for neural tube formation and is essential for normal heart development and function. Also, it is a part of a group of proteins characterized by a novel structural motif, the JmjC domain, which is implicated in chromatin regulation through histone demethylation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: JARD2 antibody; jumonji homolog; jumonji, AT rich interactive domain 2; jumonji-like protein; Jumonji/ARID domain-containing protein 2; Protein Jumonji
基因别名: JARID2; JMJ
UniProt ID: (Human) Q92833
Entrez Gene ID: (Human) 3720
negative regulation of transcription from RNA polymerase II promoter
liver development
transcription, DNA-templated
central nervous system development
negative regulation of cell proliferation
covalent chromatin modification
negative regulation of histone methylation
negative regulation of gene expression, epigenetic
negative regulation of transcription, DNA-templated
spleen development
thymus development
stem cell differentiation
positive regulation of histone H3-K9 methylation
