Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 3
JIK Antibody (PA5-116005) in ICC/IF
Immunocytochemistry analysis of JIK in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-116005). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Green) and DAPI.
产品信息
PA5-116005
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human TAOK3(Accession Q9H2K8), corresponding to amino acid residues Q534-K584.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2900639
产品详细信息
Antibody detects endogenous levels of total TAOK3.
靶标信息
TAOK3 (JIK) is a serine/threonine kinase that is a member of the GCK-like subfamily of the STE20 kinase family. JIK is ubiquitously expressed in human tissues, inhibits JNK and has been implicated in cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Axotomy-related gene 357 protein; CTCL-associated antigen HD-CL-09; Cutaneous T-cell lymphoma-associated antigen HD-CL-09; Dendritic cell-derived protein kinase; DKFZp666H245; EC 2.7.11.1; FLJ31808; hKFC-A; JNK/SAPK-inhibitory kinase; Jun kinase-inhibitory kinase; Kinase from chicken homolog A; Serine/threonine-protein kinase TAO3; STE2-like kinase; STE20-like kinase; tao; Thousand and one amino acid protein 3
基因别名: 2900006A08Rik; A130052D22; A430105I05Rik; Arg357; DPK; JIK; KDS; MAP3K18; TAOK3
UniProt ID: (Human) Q9H2K8, (Mouse) Q8BYC6, (Rat) Q53UA7
Entrez Gene ID: (Human) 51347, (Mouse) 330177, (Rat) 304530
protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
protein kinase inhibitor activity
protein binding
ATP binding
transferase activity
nucleotide binding
protein kinase activity
MAP kinase kinase kinase activity
kinase activity
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
MAPK cascade
DNA repair
protein phosphorylation
negative regulation of protein kinase activity
cellular response to DNA damage stimulus
mitotic G2 DNA damage checkpoint
positive regulation of stress-activated MAPK cascade
positive regulation of JUN kinase activity
negative regulation of JNK cascade
positive regulation of JNK cascade
protein autophosphorylation
activation of MAPKK activity
regulation of mitotic cell cycle
phosphorylation
signal transduction by protein phosphorylation
stress-activated protein kinase signaling cascade
regulation of apoptotic process
intracellular signal transduction
