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产品信息
PA5-142263
产品规格
种属反应
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide with sequence CQLLPQHQVPAY.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2932916
产品详细信息
Additional Information: This antibody is expected NOT to cross-react with Jun oncogen (NP_002219.1, GeneID 3725).
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000.
靶标信息
JunD is a transcription factor which is coded by JunD gene. JunD transcriptional activity is modulated by phosphorylation in response to cellular stress via the c-Jun N terminal kinase (JNK)/Stress-Activated Protein Kinase (SAPK) family of protein kinase. Jun proteins are capable of forming dimers with Fos, ATF and CREB family transcription factors to form the AP-1 complex that differentially regulates a variety of target genes involved in cellular growth, proliferation, differentiation and apoptosis. Also, JunD plays an important role in metabolism via modulation of IGF-1 signaling pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: JUN D; Jun proto-oncogene related gene d; Jun proto-oncogene related gene d1; Oncogene Jun-D; Transcription factor AP-1 subunit JunD; transcription factor jun-D; Transcription factor JunD
基因别名: Jun-d; Jund; Jund1
UniProt ID: (Mouse) P15066
Entrez Gene ID: (Mouse) 16478
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
protein binding
transcription factor binding
ligand-dependent nuclear receptor binding
enzyme binding
sequence-specific DNA binding
transcription regulatory region DNA binding
basic leucine zipper transcription factor
negative regulation of transcription from RNA polymerase II promoter
osteoblast development
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
response to radiation
response to mechanical stimulus
regulation of cell death
response to lipopolysaccharide
cellular response to hormone stimulus
response to cytokine
regulation of cell proliferation
response to drug
positive regulation of osteoblast differentiation
positive regulation of transcription from RNA polymerase II promoter
response to cAMP
regulation of cell cycle
cellular response to calcium ion
