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Recommended positive controls: H1299, HCT116.
Predicted reactivity: Mouse (97%), Rat (98%), Chicken (85%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Cadherins constitute a family of transmembrane glycoproteins involved in Ca2+-dependent cell-cell interactions. The members of this family are differentially expressed in various tissues. They function in the maintenance of tissue integrity and morphogenesis. Cadherins are divided into type I and type II subgroups. Type I cadherins include epithelial cadherin (E-cadherin, cadherin-1 or uvomorulin), neural cadherin (N-cadherin or cadherin-2), placental cadherin (P-cadherin or cadherin-3) and retinal cadherin (R-cadherin or cadherin-4), whereas kidney cadherin (K-cadherin or cadherin-6) and osteoblast cadherin (OB-cadherin or cadherin-11) are type II cadherins. Cadherin-6 is expressed in the proximal tubule epithelium of the kidney from which most renal cell carcinomas are derived.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CADH6; cadherin 6, type 2, K-cadherin (fetal kidney); Cadherin-6; Cadherin6; k cadherin; K-cadherin; Kidney cadherin
基因别名: CAD6; CDH6; KCAD
UniProt ID: (Human) P55285
Entrez Gene ID: (Human) 1004
分子生物学功能:
cadherin