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A suggested positive control is NIH-3T3 cell lysate.
PA5-34533 can be used with blocking peptide PEP-1576.
Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. KANK1 (KN motif and ankyrin repeat domain-containing protein 1), also known as ANKRD15, is a 1,352 amino acid protein that contains at least 12 exons and 5 ANK repeats. It binds to beta-catenin and regulates its subcellular distribution. KANK1 is ubiquitously expressed and localizes to cytoplasm. It may function as a tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ankyrin repeat domain 15; Ankyrin repeat domain-containing protein 15; Kidney ankyrin repeat-containing protein; KN motif and ankyrin repeat domain-containing protein 1
基因别名: A930031B09Rik; ANKRD15; AU015049; AW121052; CPSQ2; D330024H06Rik; KANK; KANK1; KIAA0172; mKIAA0172
UniProt ID: (Human) Q14678
Entrez Gene ID: (Human) 23189, (Mouse) 107351