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KCC4 Antibody (PA5-88472) in WB
Western blot analysis of KCC4 in extracts of various cell lines. Samples were incubated with KCC4 Polyclonal antibody (Product # PA5-88472) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
PA5-88472
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human SLC12A7 (NP_0065892)
偶联物
形式
Liquid
浓度
1.02 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2804934
产品详细信息
Immunogen sequence: MPTNFTVVPV EAHADGGGDE TAERTEAPGT PEGPEPERPS PGDGNPRENS PFLNNVEVEQ ESFFEGKNMA; Positive Samples: Mouse kidney, Mouse liver, Rat kidney; Cellular Location: Cell membrane, Multi-pass membrane protein
靶标信息
Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification. [UniProt]
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Electroneutral potassium-chloride cotransporter 4; furosemide-sensitive KCl cotransporter 4; K-Cl cotransporter 4; K-Cl cotransporter KCC4; slc12a7 {ECO:0000312|EMBL:AAH86339.1, ECO:0000312|RGD:1359672}; solute carrier family 12 (potassium/chloride transporters), member 7; Solute carrier family 12 member 7
基因别名: AA408796; D13Ertd261e; Kcc4; Slc12a7
UniProt ID: (Rat) Q5RK27, (Mouse) Q9WVL3
Entrez Gene ID: (Rat) 308069, (Mouse) 20499
