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QED Bioscience

KDEL Receptor Monoclonal Antibody (KR-10)

查看其他17个KDEL抗体

说明书

实验方案

技术支持

说明书

实验方案

技术支持

抗体检测数据 (2)

Application

KDEL Receptor Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 2

KDEL Receptor Antibody (11078-100UG) in ICC/IF

Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-KDEL Receptor Monoclonal Antibody, Clone KR-10 (11078). Tissue: NRK cells. Species: Rat. Primary Antibody: Mouse Anti-KDEL Receptor Monoclonal Antibody (11078) at 1:1000. Secondary Antibody: APC Goat Anti-Mouse (red). Counterstain: DAPI (blue) nuclear stain. KR-10 staining red; DAPI staining blue. Merged images. Courtesy of: Institute of Mol. ... View More

KDEL Receptor Antibody in Western Blot (WB)

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产品信息

11078-100UG

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1 µg/mL

免疫细胞化学 (ICC/IF)

1:1,000

产品规格

种属反应

Bovine, Dog, Chicken, Fruit fly, Hamster, Human, Mouse, Non-human primate, Sheep, Pig, Rabbit, Rat, Xenopus

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

KR-10

抗原

Peptide corresponding to aa 192-212 of bovine KDEL receptor

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偶联物

Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.2, with 50% glycerol

内含物

0.09% sodium azide

保存条件

2-8°C

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

The sequence Lys-Asp-Glu-Leu (KDEL) or a closely related sequence, is present at the carboxy-terminus of soluble endoplasmic reticulum (ER) resident proteins and some membrane proteins. 78 and 94 kDa glucose regulated proteins, GRP78 and GRP94 respectively, and protein disulfide isomerase (PDI) all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: 108K heat shock protein; 108K HSP; 78 kDa glucose-regulated protein; 78-kD glucose-regulated protein precursor; 94 kDa glucose-regulated protein; 94 kDa glucose-regulated protein {ECO:0000250|UniProtKB:P08113}; 98 kDa protein kinase; Binding-immunoglobulin protein; BiP; BiP protein; CG5183-PA; CG5183-PB; CG5183-PC; Endoplasmic reticulum chaperone BiP; endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; Endoplasmic reticulum resident protein 99; Endoplasmin; endoplasmin {ECO:0000250|UniProtKB:P08113}; endothelial cell (HBMEC) glycoprotein; epididymis luminal protein 35; epididymis secretory sperm binding protein Li 125m; epididymis secretory sperm binding protein Li 89n; ER lumen protein retaining receptor 1; ER lumen protein retaining receptor 2; ER lumen protein-retaining receptor; ER lumen protein-retaining receptor 1; ERp99; glucose regulated protein, 78 kDa; glucose-regulated protein; glucose-regulated protein GRP94; glucose-regulated protein, 78kDa; gp96 homolog; GRP 78; GRP-78; GRP-94; GRP94; Heat shock 108 kDa protein; heat shock 70 kDa protein 5; heat shock 70 kDa protein 5a; heat shock 70kD protein 5; heat shock 70kD protein 5 (glucose-regulated protein, 78kD); heat shock 70kDa protein 5 (glucose-regulated protein); heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa); heat shock protein 108; heat shock protein 108.; heat shock protein 5; Heat shock protein 70 family protein 5; Heat shock protein 90 kDa beta member 1; heat shock protein 90 kDa beta member 1 {ECO:0000250|UniProtKB:P08113}; heat shock protein 90, beta (Grp94), member 1; heat shock protein 90kDa beta (Grp94), member 1; heat shock protein 90kDa beta family member 1; heat shock protein 90kDa beta, member 1; Heat shock protein family A member 5; Heat shock protein family C member 4; heavy-chain binding protein BiP; HSP 108; hsp108; hsp70; HSP70 family protein 5; HSP90 beta; hsp90b1 {ECO:0000250|UniProtKB:P08113}; immunoglobulin binding protein; Immunoglobulin heavy chain-binding protein; KDEL; KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1; KDEL endoplasmic reticulum protein retention receptor 1; KDEL receptor 1; KDEL receptor-like protein; KDEL-receptor; KdelR-PA; KdelR-PB; KdelR-PC; lethal (2) 31Em; Lys-Asp-Glu-Leu; Polymorphic tumor rejection antigen 1; PPK 98; Putative MAPK-activating protein PM23; RP23-446N16.1; Steroidogenesis-activator polypeptide; stress-inducible tumor rejection antigen gp96; Transferrin-binding protein; transforming growth factor alpha regulated gene 2; tumor rejection antigen (gp96) 1; Tumor rejection antigen 1; Tumor rejection antigen gp96; XAP-1 antigen

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基因别名: 8030486F04Rik; AL022860; AU019543; AW215843; baffled; BEST:CK00230; BIP; BiP/Grp78; CG5183; CK00230; D2Wsu141e; D2Wsu17e; Dmel\CG5183; Dmel_CG5183; dmErd2; ECGP; endoplasmin; ERD2; ERD2.1; ERp99; GP96; GRP78; GRP94; HDEL; HEL-S-125m; HEL-S-89n; HEL35; Hsce70; hsp108; HSP90B1; HSPA5; hspa5a; HSPC4; I79_019946; I79_020931; KDELR; KDELR1; l(2)31Em; l(2)k00311; mBiP; MIF2; PM23; ppk98; SEZ-7; Sez7; TA-3; Targ2; Tra-1; TRA1; XAP-1; XELAEV_180384511mg

功能

ATP binding RNA binding protein phosphatase binding low-density lipoprotein particle receptor binding unfolded protein binding calcium ion binding protein binding virion binding ATPase activity heat shock protein binding protein binding involved in protein folding misfolded protein binding protein domain specific binding ubiquitin protein ligase binding ribosome binding glycoprotein binding enzyme binding chaperone binding cadherin binding involved in cell-cell adhesion nucleotide binding KDEL sequence binding ER retention sequence binding molecular_function Hsp90 family chaperone membrane trafficking regulatory protein

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