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Immunogen sequence: GQGQGRGCSR GRGHGCCTRE LGTEEPTVQP ASKRRLLMGT RSRAQGHRPQ LPLANDLMTN LS
Highest antigen sequence identity to the following orthologs: Mouse - 31%, Rat - 35%.
The protein encoded by this intronless gene is a member of a large family of histone lysine demethylases, which use oxygen and 2-oxoglutarate to demethylate di- and trimethylated lys9 of histone H3. Derepression of genes by demethylases is sometimes involved in viral infection or carcinogenesis, so inhibitors of these enzymes are desired.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: [histone H3]-trimethyl-L-lysine(9) demethylase 4E; KDM4D-like protein; lysine (K)-specific demethylase 4E; Lysine-specific demethylase 4D-like; Lysine-specific demethylase 4E
基因别名: JMJD2E; KDM4DL; KDM4E
UniProt ID: (Human) B2RXH2
Entrez Gene ID: (Human) 390245
分子生物学功能:
histone modifying enzyme